Now showing items 1-20 of 24

    • Antibacterial coatings on medical devices 

      Ivanova, Kristina Dimitrova; Bassegoda Puigdomenech, Arnau; Tzanov, Tzanko (Elsevier, 2017-11-02)
      Part of book or chapter of book
      Restricted access - publisher's policy
    • Antibacterial polyurethane foams with incorporated lignin-capped silver nanoparticles for chronic wound treatment 

      Morena Gatius, Ángela Gala; Ivanova, Kristina Dimitrova; Pérez Rafael, Silvia; Sánchez Soto, Miguel; Tzanov, Tzanko (2020-02-26)
      Article
      Restricted access - publisher's policy
      Lignin-capped silver nanoparticles were incorporated in situ into polyurethane foams during their polymerization to obtain multifunctional materials suitable for chronic wound dressing. Lignin with increased phenolic ...
    • Antibiofilm poly(carboxybetaine methacrylate) hydrogels for chronic wounds dressings 

      Ruseva, Konstans; Ivanova, Kristina Dimitrova; Todorova, Katerina; Vladov, Ivelin; Nanev, Vesselin; Tzanov, Tzanko; Hinojosa-Caballero, Dolores; Argirova, Maya; Vassileva, Elena (Elsevier, 2020-04-12)
      Article
      Restricted access - publisher's policy
      The current study demonstrates the benefits of poly(carboxybetaine methacrylate) hydrogels in chronic wound healing. These hydrogels demonstrate high absorbing capacity upon swelling in salt solutions thus revealing great ...
    • Antibody-enabled antimicrobial nanocapsules for selective elimination of Staphylococcus aureus 

      Ivanova, Kristina Dimitrova; Asenova Ivanova, Aleksandra; Ramon Portés, Eva; Hoyo Pérez, Javier; Sanchez-Gomez, Susana; Tzanov, Tzanko (2020-07-16)
      Article
      Restricted access - publisher's policy
      Targeted bactericide nanosystems hold significant promise to improve the efficacy of existing antimicrobials for treatment of severe bacterial infections, minimizing the side effects and lowering the risk of antibiotic ...
    • Antimicrobial lightweight materials and components 

      Morena Gatius, Ángela Gala; Ferreres Cabanes, Guillem; Ivanova, Kristina Dimitrova; Pérez Rafael, Silvia; Tzanov, Tzanko (Elsevier, 2020-12-02)
      Part of book or chapter of book
      Restricted access - publisher's policy
      Lightweight materials and components have gained remarkable scientific and technological importance in the recent times as the main drivers of innovation. They are finding widespread use across all industry sectors to ...
    • Bacteria-responsive multilayer coatings comprising polycationic nanospheres for bacteria biofilm prevention on urinary catheters 

      Francesko, Antonio; Macedo Fernandes, Margarida Maria; Ivanova, Kristina Dimitrova; Tzanov, Tzanko (2016-01-21)
      Article
      Open Access
      This work reports on the development of infection-preventive coatings on silicone urinary catheters that contain in their structure and release on demand antibacterial polycationic nanospheres. Polycationic aminocellulose ...
    • Bottom-up layer-by-layer assembling of antibacterial freestanding nanobiocomposite films 

      Francesko, Antonio; Ivanova, Kristina Dimitrova; Hoyo Pérez, Javier; Pérez-Rafael, Silvia; Petkova, Petya; Fernandes Macedo, Margarida Maria; Heinze, Thomas; Mendoza Gómez, Ernesto; Tzanov, Tzanko (2018-07-27)
      Article
      Open Access
      In this study, freestanding nanobiocomposite films were obtained by the sequential deposition of biopolymer-capped silver nanoparticles (AgNPs) and hyaluronic acid (HA). At first, dispersions ofAgNPs decorated with chitosan ...
    • Electrical evaluation of bacterial virulence factors using nanopores 

      Escosura Muñiz, Alfredo de la; Ivanova, Kristina Dimitrova; Tzanov, Tzanko (2019-03-19)
      Article
      Open Access
      In this work, we propose a novel methodology for electrical monitoring using nanoporous alumina membranes of virulence factors secreted by bacterial pathogens. Bacterial hyaluronidase (HYAL), which is produced by a number ...
    • Enzyme multilayer coatings inhibit Pseudomonas aeruginosa biofilm formation on urinary catheters 

      Ivanova, Kristina Dimitrova; Macedo Fernandes, Margarida Maria; Mendoza Gómez, Ernesto; Tzanov, Tzanko (2015-01-15)
      Article
      Open Access
      Bacteria use a signaling mechanism called quorum sensing (QS) to form complex communities of surface-attached cells known as biofilms. This protective mode of growth allows them to resist antibiotic treatment and originates ...
    • Escherichia coli and pseudomonas aeruginosa eradication by nano-penicillin G 

      Macedo Fernandes, Margarida Maria; Ivanova, Kristina Dimitrova; Francesko, Antonio; Rivera, Diana; Torrent Burgués, Juan; Mendoza Gómez, Ernesto; Tzanov, Tzanko (2016-06-09)
      Article
      Open Access
      The transformation of penicillin G into nano/micro-sized spheres (nanopenicillin) using sonochemical technology was explored as a novel tool for the eradication of Gram-negative bacteria and their biofilms. Known by its ...
    • Immobilization of antimicrobial core-shell nanospheres onto silicone for prevention of Escherichia coli biofilm formation 

      Macedo Fernandes, Margarida Maria; Ivanova, Kristina Dimitrova; Mendoza Gómez, Ernesto; Tzanov, Tzanko; Francesko, Antonio (2016-09-16)
      Article
      Open Access
      Escherichia coli (E. coli) strains are among the most frequently isolated microorganisms in urinary tract infections able to colonize the surface of urinary catheters and form biofilms. These biofilms are highly resistant ...
    • Inhibition of quorum-sensing: A new paradigm in controlling bacterial virulence and biofilm formation 

      Asenova Ivanova, Aleksandra; Ivanova, Kristina Dimitrova; Tzanov, Tzanko (Springer Nature, 2018-05-31)
      Part of book or chapter of book
      Restricted access - publisher's policy
      Bacterial pathogens coordinate the expression of multiple virulence factors and formation of biofilms in cell density dependent manner, through a phenomenon named quorum sensing (QS). Protected in the biofilm community, ...
    • Innovative approaches for controlling clinically relevant biofilms: current trends and future prospects 

      Ivanova, Kristina Dimitrova; Tzanov, Tzanko; Hoyo Pérez, Javier; Ramon Portés, Eva (2017-01-05)
      Article
      Open Access
      Bacteria that colonize and form biofilms on living tissues and medical devices are a global healthcare concern. They cause life threatening infections and are associated with increased mortality and morbidity in the ...
    • Interaction of silver-lignin nanoparticles with mammalian mimetic membranes 

      Hoyo Pérez, Javier; Ivanova, Kristina Dimitrova; Torrent Burgués, Juan; Tzanov, Tzanko (Frontiers Media SA, 2020-05-08)
      Article
      Open Access
      Silver nanoparticles (AgNPs) have broad spectrum antibacterial activity, but their toxicity to human cells has raised concerns related to their use as disinfectants or coatings of medically relevant surfaces. To address ...
    • Layer-by-Layer coating of aminocellulose and quorum quenching acylase on silver nanoparticles synergistically eradicate bacteria and their biofilms 

      Asenova Ivanova, Aleksandra; Ivanova, Kristina Dimitrova; Tied, Antje; Heinze, Thomas; Tzanov, Tzanko (2020-04-24)
      Article
      Open Access
      The emergence of antibiotic-resistant bacteria and the failure of the existing antibacterial therapeutics call for development of novel treatment strategies. Furthermore, the formation of bacterial biofilms restricts drug ...
    • Layer-by-layer decorated nanoparticles with tunable antibacterial and antibiofilm properties against both gram-positive and gram-negative bacteria 

      Asenova Ivanova, Aleksandra; Ivanova, Kristina Dimitrova; Hoyo Pérez, Javier; Sanchez-Gomez, Susana; Heinze, Thomas; Tzanov, Tzanko (2018-01-09)
      Article
      Open Access
      acteria-mediated diseases are a global healthcare concern due to the development and spread of antibiotic resistant strains. Cationic compounds are considered membrane active biocidal agents having a great potential to ...
    • Multifunctional ZnO NPs-chitosan-gallic acid hybrid nanocoating to overcome contact lenses associated conditions and discomfort 

      Hoyo Pérez, Javier; Ivanova, Kristina Dimitrova; Guaus Guerrero, Ester; Tzanov, Tzanko (2019-02-13)
      Article
      Restricted access - publisher's policy
      Contact lenses (CL) provide visual correction but their use may also induce several adverse effects causative of discomfort and conditions that lead to stop or discontinue their use. Discomfort is mainly caused by insufficient ...
    • Nanostructured coatings for controlling bacterial biofilms and antibiotic resistance 

      Ivanova, Kristina Dimitrova (Universitat Politècnica de Catalunya, 2017-01-27)
      Doctoral thesis
      Open Access
      The accelerated emergence of drug resistant bacteria is one of the most serious problems in healthcare and the difficulties in finding new antibiotics make it even more challenging. To overcome the action of antibiotics ...
    • Nanotransformation of vancomycin overcomes the intrinsic resistance of Gram-negative bacteria 

      Ivanova, Kristina Dimitrova; Hoyo Pérez, Javier; Francesko, Antonio; Tzanov, Tzanko; Fernandes, Margarida M.; Pérez Rafael, Silvia (2017-04-10)
      Article
      Open Access
      The increased emergence of antibiotic-resistant bacteria is a growing public health concern, and although new drugs are constantly being sought, the pace of development is slow compared with the evolution and spread of ...
    • Poly(sulfobetaine methacrylate)/poly(ethylene glycole) hydrogels for chronic wounds management 

      Ruseva, Konstans; Ivanova, Kristina Dimitrova; Todorova, Katerina; Gabrashanska, Margarita; Hinojosa-Caballero, Dolores; Tzanov, Tzanko; Vassileva, Elena (Elsevier, 2019-05-14)
      Article
      Restricted access - publisher's policy
      Polyzwitterions (PZI) recently emerged as biomaterials with excellent bio- and haemo-compatibility, demonstrating lower protein adsorption on their surfaces even compared to the golden standard in the field – poly(ethylene ...