Now showing items 1-20 of 28

    • A General Equilibrium Model to Study Intracellular Calcium Homeostasis. New Insights on Ventricular Function 

      Álvarez Lacalle, Enrique; Conesa Ortega, David; Echebarría Domínguez, Blas; Shiferaw, Yohannes; Peñaranda Ayllón, Angelina; Rodríguez Cantalapiedra, Inma (2018)
      Conference report
      Open Access
    • Acoustic evaluation of modular greenery noise barriers 

      Lacasta Palacio, Ana María; Peñaranda Ayllón, Angelina; Rodríguez Cantalapiedra, Inma; Auguet Sangrá, Carlota E.; Bures, S.; Urrestarazu, M. (2016-12-01)
      Article
      Open Access
      Green noise barriers have become an alternative means of reducing urban traffic noise. In this paper, the acoustic performance of a modular greenery noise barrier is evaluated. In situ measurements of noise reflection were ...
    • Are SR Ca content fluctuations or SR refractoriness the key to atrial cardiac alternans?: insights from a human atrial model 

      Lugo Vélez, Carlos Antonio; Rodríguez Cantalapiedra, Inma; Peñaranda Ayllón, Angelina; Hove-Madsen, Leif; Echebarría Domínguez, Blas (2014-06-01)
      Article
      Restricted access - publisher's policy
      Despite the important role of electromechanical alternans in cardiac arrhythmogenesis, its molecular origin is not well understood. The appearance of calcium alternans has often been associated to fluctuations in the ...
    • Calcium alternans is a global order-disorder phase transition. Robustness on Ryanodine Receptor release dynamics 

      Álvarez Lacalle, Enrique; Peñaranda Ayllón, Angelina; Rodríguez Cantalapiedra, Inma; Shiferaw, Yohannes; Echebarría Domínguez, Blas (2015)
      Conference report
      Open Access
      Electromechanical alternans is a beat-to-beat alterna- tion in the strength of contraction of a cardiac cell which appears often due to an instability of calcium cycling. The global calcium signal in cardiomyocytes is ...
    • Calcium alternans is a global order-disorder phase transition: robustness on ryanodine receptor release dynamics 

      Álvarez Lacalle, Enrique; Peñaranda Ayllón, Angelina; Rodríguez Cantalapiedra, Inma; Shiferaw, Yohannes; Echebarría Domínguez, Blas (2016-01-01)
      Article
      Open Access
      Electromechanical alternans is a beat-to-beat alterna- tion in the strength of contraction of a cardiac cell which appears often due to an instability of calcium cycling. The global calcium signal in cardiomyocytes is ...
    • Calcium alternans produced by increased sarcoplasmic reticulum refractoriness 

      Rodríguez Cantalapiedra, Inma; Lugo Vélez, Carlos Antonio; Peñaranda Ayllón, Angelina; Echebarría Domínguez, Blas (2011-09-29)
      Article
      Open Access
      Despite the important role of electro-mechanical alternans in cardiac arrhythmogenesis, its molecular origin is not well understood. In this paper we want to study alternans that can be associated with alternations in the ...
    • Calcium alternans produced by increased sarcoplasmic reticulum refractoriness 

      Rodríguez Cantalapiedra, Inma; Lugo, Carlos; Peñaranda Ayllón, Angelina; Echebarría Domínguez, Blas (IEEE Computer Society Publications, 2011)
      Conference report
      Restricted access - publisher's policy
      Despite the important role of electro-mechanical alternans in cardiac arrhythmogenesis, its molecular origin is not well understood. In this paper we want to study alternans that can be associated with alternations in ...
    • Cardiac dynamics: modeling the Brugada syndrome 

      Rodríguez Cantalapiedra, Inma; Echebarría Domínguez, Blas; Peñaranda Ayllón, Angelina (2007)
      Conference report
      Open Access
      Este trabajo analiza mediante un modelo matemático reducido de corrientes ionicas la posibilidad de aparición de arritmias cardiacas.
    • Corriente alterna : teoría y problemas 

      Castellví Gironès, Pedro Juan; Peñaranda Ayllón, Angelina (Universitat Politècnica de Catalunya, 2009)
      Lecture notes
      Open Access
    • Dependency of calcium alternans on Ryanodine Receptor Refractoriness 

      Álvarez Lacalle, Enrique; Rodríguez Cantalapiedra, Inma; Peñaranda Ayllón, Angelina; Cinca, J.; Hove-Madsen, Leif; Echebarría Domínguez, Blas (2013-02-04)
      Article
      Open Access
      Background Rapid pacing rates induce alternations in the cytosolic calcium concentration caused by fluctuations in calcium rele However, the relationship between calcium alternans and refractoriness of the SR calcium ...
    • Effect of RyR2 refractoriness and hypercalcemia on calcium overload, spontaneous release, and calcium alternans 

      Álvarez Lacalle, Enrique; Peñaranda Ayllón, Angelina; Rodríguez Cantalapiedra, Inma; Hove-Madsen, Leif; Echebarría Domínguez, Blas (2013)
      Article
      Restricted access - publisher's policy
      In this work we use a computer model of a ventricular rabbit myocyte to study several factors that affect sarcoplasmic reticulum (SR) calcium load, such as hypercalcemia, SR calcium buffering, or ryanodine receptor ...
    • Effects of small conductance calcium activated potassium channels in atrial myocytes 

      Peñaranda Ayllón, Angelina; Echebarría Domínguez, Blas; Álvarez Lacalle, Enrique; Rodríguez Cantalapiedra, Inma (IEEE Computer Society Conference Publishing Services (CPS), 2017)
      Conference lecture
      Open Access
      Among the different potassium channels present in cardiac myocytes, the small conductance Ca2+ activated potassium channels (SK channels) are particular because they are affected by changes in intracellular calcium. The ...
    • Gap junction dynamics induces localized conductance bistability in cardiac tissue 

      Hawks, Claudia; Elorza Barbajero, Jorge; Witt, Annette; Laroze, David; Rodríguez Cantalapiedra, Inma; Peñaranda Ayllón, Angelina; Echebarría Domínguez, Blas; Bragard, Jean (2019-07-01)
      Article
      Open Access
      Connexins are specialized ionic channels that control the action potential propagation between cardiac myocytes. In this paper, we study the connexin dynamics in a one-dimensional model of cardiac tissue. We show that the ...
    • Influence of gap junction dynamics on the stability of reentrant waves in cadiac tissue 

      Hawks, Claudia; Elorza Barbajero, Jorge; Echebarría Domínguez, Blas; Rodríguez Cantalapiedra, Inma; Peñaranda Ayllón, Angelina; Bragard, Jean (2015)
      Conference report
      Open Access
      Constant conductances are often assumed when model- ing cardiac tissue. However experimental evidences have shown that gap junctions (GJ) actually connect adjacent cardiac myocytes. These GJ are complex proteins of ...
    • Influence of gap junction dynamics on the stability of reentrant waves in cardiac tissue 

      Hawks, Claudia; Elorza Barbajero, Jorge; Echebarría Domínguez, Blas; Rodríguez Cantalapiedra, Inma; Peñaranda Ayllón, Angelina; Bragard, Jean (2016-01-01)
      Conference lecture
      Open Access
      Constant conductances are often assumed when model- ing cardiac tissue. However experimental evidences have shown that gap junctions (GJ) actually connect adjacent cardiac myocytes. These GJ are complex proteins of ...
    • Mechanisms Underlying Electro-Mechanical Cardiac Alternans 

      Echebarría Domínguez, Blas; Álvarez Lacalle, Enrique; Rodríguez Cantalapiedra, Inma; Peñaranda Ayllón, Angelina (Springer, 2016-02-29)
      Part of book or chapter of book
      Restricted access - publisher's policy
      Electro-mechanical cardiac alternans consists in beat-to-beat changes in the strength of cardiac contraction. Despite its important role in cardiac arrhythmogenesis, its molecular origin is not well understood. The appearance ...
    • Minimal model for calcium alternans due to SR release refractoriness 

      Rodríguez Cantalapiedra, Inma; Álvarez Lacalle, Enrique; Peñaranda Ayllón, Angelina; Echebarría Domínguez, Blas (Institute of Physics (IOP), 2017-09-07)
      Article
      Open Access
      In the heart, rapid pacing rates may induce alternations in the strength of cardiac contraction, termed pulsus alternans. Often, this is due to an instability in the dynamics of the intracellular calcium concentration, ...
    • Modeling calcium dynamics in human atria 

      Rodríguez Cantalapiedra, Inma; Lugo Vélez, Carlos Antonio; Peñaranda Ayllón, Angelina; Hove-Madsen, Leif; Echebarría Domínguez, Blas (2014-01-02)
      Article
      Restricted access - publisher's policy
      Mathematical models of cardiac electrophysiology are an important tool to investigate the underlying mecha- nisms responsible of arrhythmias. In particular, an im- portant question is the origin of atrial fibrillation ...
    • Modeling of spatiotemporal patterns in bacterias colonies 

      Lacasta Palacio, Ana María; Rodríguez Cantalapiedra, Inma; Auguet Sangrá, Carlota E.; Peñaranda Ayllón, Angelina; Ramírez de la Piscina Millán, Laureano (American Physical Society, 1999-06-30)
      Article
      Open Access
      A diffusion-reaction model for the growth of bacterial colonies is presented. The often observed cooperative behavior developed by bacteria which increases their motility in adverse growth conditions is here introduced as ...
    • Nonlinearities due to refractoriness in SR Ca release 

      Peñaranda Ayllón, Angelina; Álvarez Lacalle, Enrique; Rodríguez Cantalapiedra, Inma; Echebarría Domínguez, Blas (Institute of Electrical and Electronics Engineers (IEEE), 2013-01-01)
      Conference lecture
      Open Access
      Calcium alternans is a pro-arrhytmic cardiac dysfunction related to beat-to-beat changes in the amplitude of intracellular calcium transient, that typically occurs at rapid pacing rates. Although oscillations in sarcoplasmic ...