Browsing by Author "Ivanova, Aleksandra Asenova"
Now showing items 1-12 of 12
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Antibacterial, antibiofilm, and antiviral farnesol-containing nanoparticles prevent Staphylococcus aureus from drug resistance development
(2022-07-07)
Article
Open AccessMultidrug antimicrobial resistance is a constantly growing health care issue associated with increased mortality and morbidity, and huge financial burden. Bacteria frequently form biofilm communities responsible for numerous ... -
Antibody-enabled antimicrobial nanocapsules for selective elimination of Staphylococcus aureus
(2020-07-16)
Article
Open AccessTargeted bactericide nanosystems hold significant promise to improve the efficacy of existing antimicrobials for treatment of severe bacterial infections, minimizing the side effects and lowering the risk of antibiotic ... -
Bio-based nano-enabled cosmetic formulations for the treatment of cutibacterium acnes-associated skin infections
(2023-02-09)
Article
Open AccessAcne is a common chronic skin condition with serious physical and psychosocial consequences. In some cases, the appearance of pimples, whiteheads, or blackheads on the face, neck, and back may lead to scarring, disfiguring, ... -
Durable bio-based nanocomposite coating on urinary catheters prevents early-stage CAUTI-associated pathogenicity
(John Wiley & sons, 2025-02-10)
Article
Open AccessRecurrent catheter-associated urinary tract infections (CAUTIs) in catheterized patients, increase their morbidity and hospital stay at substantial costs for healthcare systems. Hence, novel and efficient strategies for ... -
Inhibition of quorum-sensing: A new paradigm in controlling bacterial virulence and biofilm formation
(Springer Nature, 2018-05-31)
Part of book or chapter of book
Restricted access - publisher's policyBacterial pathogens coordinate the expression of multiple virulence factors and formation of biofilms in cell density dependent manner, through a phenomenon named quorum sensing (QS). Protected in the biofilm community, ... -
Integrated biofilm dispersion and virulence responsiveness for targeted treatment of pseudomonas aeruginosa infection in lungs
(2024-11-12)
Article
Open AccessThe self-organization of microbes into biofilms provides multiple benefits including tolerance to mechanical stress and resistance to immune defences and antibiotics. Coupled to a compromised mucociliary function, these ... -
Layer-by-Layer coating of aminocellulose and quorum quenching acylase on silver nanoparticles synergistically eradicate bacteria and their biofilms
(2020-04-24)
Article
Open AccessThe emergence of antibiotic-resistant bacteria and the failure of the existing antibacterial therapeutics call for development of novel treatment strategies. Furthermore, the formation of bacterial biofilms restricts drug ... -
Layer-by-layer decorated nanoparticles with tunable antibacterial and antibiofilm properties against both gram-positive and gram-negative bacteria
(2018-01-09)
Article
Open Accessacteria-mediated diseases are a global healthcare concern due to the development and spread of antibiotic resistant strains. Cationic compounds are considered membrane active biocidal agents having a great potential to ... -
Nano-formulation endows quorum quenching enzyme-antibiotic hybrids with improved antibacterial and antibiofilm activities against pseudomonas aeruginosa
(2022-07-11)
Article
Open AccessThe emergence of antibiotic resistant bacteria coupled with the shortage of efficient antibacterials is one of the most serious unresolved problems for modern medicine. In this study, the nano-hybridization of the clinically ... -
Nanomaterials for controlling bacterial pathogens and resistance occurrence
(Universitat Politècnica de Catalunya, 2022-03-11)
Doctoral thesis
Open Accesslnfectious diseases are the leading cause of death worldwide while the constantly raising antimicrobial resistance (AMR) is a major concern for the public health. During the infection establishment bacteria! pathogens ... -
Simultaneous ultrasound-assisted hybrid polyzwitterion/antimicrobial peptide nanoparticles synthesis and deposition on silicone urinary catheters for prevention of biofilm-associated infections
(2021-11-21)
Article
Open AccessNosocomial infections caused by antibiotic-resistant bacteria are constantly growing healthcare threats, as they are the reason for the increased mortality, morbidity, and considerable financial burden due to the poor ... -
Sonochemically engineered nano-enabled zinc oxide/amylase coatings prevent the occurrence of catheter-associated urinary tract infections
(Elsevier, 2021-10-26)
Article
Open AccessCatheter-associated urinary tract infections (CAUTIs), caused by biofilms, are the most frequent health-care associated infections. Novel antibiofilm coatings are needed to increase the urinary catheters' life-span, decrease ...
