Browsing by Author "Garriga Solé, Pere"
Now showing items 1-20 of 45
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A dual role for EDEM1 in the processing of rod opsin
Kosmaoglou, Maria; Kanuga, Naheed; Aguila Cerda, Mónica; Garriga Solé, Pere; Cheetham, Michael E (2009-12)
Article
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Alteraciones genéticas asociadas a retinosis pigmentaria en proteínas del ciclo visual I. Aspectos generales y clasificación
Valle Mendoza, Luis Javier del; Garriga Solé, Pere; Bosch Presegué, Laia; Götzens García, Guadalupe; Urtubia Vicario, César; Ramon Portés, Eva (PUNTEX, 2002-11)
Article
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Alteraciones genéticas asociadas a retinosis pigmentaria en proteínas del ciclo visual II. Descripción de las proteínas más relevantes
Valle Mendoza, Luis Javier del; Garriga Solé, Pere; Bosch Presegué, Laia; Götzens García, Guadalupe; Urtubia Vicario, César; Ramon Portés, Eva (PUNTEX, 2002-12)
Article
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Alterations in the photoactivation pathway of rhodopsin mutants associated with retinitis pigmentosa
Bosch Presegué, Laia; Ramon Portés, Eva; Toledo, Darwin; Cordomí Montoya, Arnau; Garriga Solé, Pere (2011-05)
Article
Restricted access - publisher's policyThe visual photoreceptor rhodopsin undergoes a series of conformational changes upon light activation, eventually leading to the active metarhodopsin II conformation, which is able to bind and activate the G-protein, transducin. ... -
Altered trafficking and unfolded protein response induction as a result of M3 muscarinic receptor impaired N-glycosylation
Romero Fernandez, Wilber; Borroto Escuela, Dasiel Óscar; Perez Alea, M.; Garcia Mesa, Y; Garriga Solé, Pere (2011-12)
Article
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Análisis molecular de mutaciones en proteinas de células fotorreceptoras asociadas a retinosis pigmentaria
Urtubia Vicario, César; Ramon Portés, Eva; Valle Mendoza, Luis Javier del; Götzens García, Guadalupe; Garriga Solé, Pere (ICM, 2002-12)
Article
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Beyond spectral tuning: human cone visual pigments adopt different transient conformations for chromophore regeneration
Srinivasan, Sundaramoorthy; Cordomí, Arnau; Ramon Portés, Eva; Garriga Solé, Pere (2016-03)
Article
Open AccessHuman red and green visual pigments are seven transmembrane receptors of cone photoreceptor cells of the retina that mediate color vision. These pigments share a very high degree of homology and have been assumed to feature ... -
Biotechnological applications at GBMI: industry-driven "bio-research"
Garriga Solé, Pere; Tzanov, Tzanko (Campus de Terrassa de la UPC, 2013-06-13)
Conference report
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Differential expression of muscarinic acetylcholine receptor subtypes in Jurkat cells and their signaling
Alea, M.P.; Borroto Escuela, Dasiel Óscar; Romero Fernandez, Wilber; Fuxe, Kjell; Garriga Solé, Pere (2011-08-15)
Article
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Dissecting the conserved NPxxY motif of the M(3) muscarinic acetylcholine receptor: Critical role of Asp-7.49 for receptor signaling and multiprotein complex formation
Borroto Escuela, Dasiel Óscar; Romero Fernandez, Wilber; Garcia Negredo, G.; Correia, Patricia A.; Garriga Solé, Pere; Fuxe, Kjell; Ciruela, Francisco (2011)
Article
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Diversity and bias through receptor–receptor interactions in GPCR heteroreceptor complexes. Focus on examples from dopamine D2 receptor heteromerization
Fuxe, Kjell; Tarakanov, Alexander; Romero Fernández, Wilber; Ferraro, Luca; Tanganelli, Sergio; Malgorzata, Filip; Agnati, Luigi F.; Garriga Solé, Pere; Díaz Cabiale, Zaida; Borroto Escuela, Dasiel Óscar (2014-05-13)
Article
Open AccessAllosteric receptor–receptor interactions in GPCR heteromers appeared to introduce an intermolecular allosteric mechanism contributing to the diversity and bias in the protomers. Examples of dopamine D2R heteromerization ... -
Docosahexaenoic acid phospholipid differentially modulates the conformation of G90V and N55K rhodopsin mutants associated with retinitis pigmentosa
Dong, Xiaoyun; Herrera Hernandez, Maria Guadalupe; Ramon Portés, Eva; Garriga Solé, Pere (2017-05-01)
Article
Open AccessRhodopsin is the visual photoreceptor of the retinal rod cells that mediates dim light vision and a prototypical member of the G protein-coupled receptor superfamily. The structural stability and functional performance of ... -
Effect of sodium valproate on the conformational stability of the visual G Protein-coupled receptor rhodopsin
Razzaghi, Neda; Fernández González, Pol; Mas Sánchez, Aina; Vila i Julià, Guillem; Pérez González, Juan Jesús; Garriga Solé, Pere (2021-05-19)
Article
Open AccessRhodopsin is the G protein-coupled receptor of rod photoreceptor cells that mediates vertebrate vision at low light intensities. Mutations in rhodopsin cause inherited retinal degenerative diseases such as retinitis ... -
Effect of trace metal Ions on the conformational stability of the visual photoreceptor rhodopsin
Wang, Feifei; Fernández González, Pol; Ramon Portés, Eva; Gómez Gutiérrez, Patricia; Morillo Cazorla, Margarita; Garriga Solé, Pere (Multidisciplinary Digital Publishing Institute (MDPI), 2023-07-01)
Article
Open AccessTrace metals are essential elements that play key roles in a number of biochemical processes governing human visual physiology in health and disease. Several trace metals, such as zinc, have been shown to play important ... -
Estructura tridimensional de la rodopsina
Valle Mendoza, Luis Javier del; Garriga Solé, Pere; Götzens García, Guadalupe; Urtubia Vicario, César; Ramon Portés, Eva; Gómez, Jesús (PUNTEX, 2002-06)
Article
Open AccessLa rodopsina es un fotopigmento localizado en las membranas discoidales de los fotorreceptores de la retina de los vertebrados que desempeña una función central en el complejo fenómeno de la visión. Determinadas alteraciones ... -
Flavonoid allosteric modulation of mutated visual rhodopsin associated with retinitis pigmentosa
Herrera Hernández, María Guadalupe; Ramon Portés, Eva; Lupala, Cecylia Severin; Tena Campos, Mercè; Pérez González, Juan Jesús; Garriga Solé, Pere (Macmillan Publishers, 2017-12-01)
Article
Open AccessDietary flavonoids exhibit many biologically-relevant functions and can potentially have beneficial effects in the treatment of pathological conditions. In spite of its well known antioxidant properties, scarce structural ... -
Functional role of positively selected amino acid substitutions in mammalian rhodopsin evolution
Fernandez-Sampedro, Miguel angel; Invergo, Brandon M.; Ramon Portés, Eva; Bertranpetit, Jaume; Garriga Solé, Pere (Macmillan Publishers, 2016-02-11)
Article
Open AccessVisual rhodopsins are membrane proteins that function as light photoreceptors in the vertebrate retina. Specific amino acids have been positively selected in visual pigments during mammal evolution, which, as products of ... -
G protein-coupled receptor heterodimerization in the brain
Borroto Escuela, Dasiel Óscar; Romero Fernandez, Wilber; Garriga Solé, Pere; Ciruela, Francisco; Narvaez, Manuel; Tarakanov, O.V.; Palkovits, Miklós; Agnati, Luigi F.; Fuxe, Kjell (2013)
Article
Restricted access - publisher's policyG protein-coupled receptors (GPCRs) play critical roles in cellular processes and signaling and have been shown to form heteromers with diverge biochemical and/or pharmacological activities that are different from those ... -
Hsp90 inhibition protects against inherited retinal degeneration
Aguilà, Mònica; Bevilacqua, Dalila; McCulley, Caroline; Schwarz, Nele; Athanasiou, Dimitra; Kanuga, Naheed; Novoselov, Sergey S.; Lange, Clemens A.K.; Ali, Robin R.; Bainbridge, James W.; Gias, Carlos; Coffey, Peter J.; Garriga Solé, Pere; Cheetham, Michael E. (2014-04-15)
Article
Open AccessThe molecular chaperone Hsp90 is important for the functional maturation of many client proteins, and inhibitors are in clinical trials for multiple indications in cancer. Hsp90 inhibition activates the heat shock response ... -
Human blue cone opsin regeneration involves secondary retinal binding with analog specificity
Srinivasan, Sundaramoorthy; Fernández Sampedro, Miguel Ángel; Morillo Cazorla, Margarita; Ramon Portés, Eva; Jiménez Rosés, Mireia; Cordomi, Arnau; Garriga Solé, Pere (2018-03-27)
Article
Open AccessHuman color vision is mediated by the red, green, and blue cone visual pigments. Cone opsins are G-protein-coupled receptors consisting of an opsin apoprotein covalently linked to the 11-cis-retinal chromophore. All visual ...