Exploració per autor "Cendra Gascón, María del Mar"
Ara es mostren els items 1-13 de 13
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Development of a ternary cyclodextrin–arginine–ciprofloxacin antimicrobial complex with enhanced stability
Vukomanovic, Marija; Gazvoda, Lea; Kurtjak, Mario; Hrescak, Jitka; Jaklic, Blaz; Moya, Laura; Cendra Gascón, María del Mar; Torrents Serra, Eduard (Springer Nature, 2022-11-12)
Article
Accés obertDesigning useful functionalities in clinically validated, old antibiotics holds promise to provide the most economical solution for the global lack of effective antibiotics, as undoubtedly a serious health threat. Here we ... -
Differential adaptability between reference strains and clinical isolates of Pseudomonas aeruginosa into the lung epithelium intracellular lifestyle
Cendra Gascón, María del Mar; Torrents Serra, Eduard (2020-01-01)
Article
Accés obertIntracellular invasion is an advantageous mechanism used by pathogens to evade host defense and antimicrobial therapy. In patients, the intracellular microbial lifestyle can lead to infection persistence ... -
Easily applicable modifications to electroporation conditions improve the transformation efficiency rates for rough morphotypes of fast-growing mycobacteria
Campo Pérez, Víctor; Cendra Gascón, María del Mar; Julian Gómez, Esther; Torrents Serra, Eduard (Elsevier, 2021-07)
Article
Accés obertElectroporation is the most widely used and efficient method to transform mycobacteria. Through this technique, fast- and slow-growing mycobacteria with smooth and rough morphotypes have been successfully transformed. ... -
Effect of different antibiotic chemotherapies on pseudomonas aeruginosa infection in vitro of primary human corneal fibroblast cells
Cendra Gascón, María del Mar; Christodoulides, Myron; Hossain, Parwez (Frontiers Media SA, 2017-08-22)
Article
Accés obertPseudomonas aeruginosa is a major cause of bacterial keratitis (BK) worldwide. Inappropriate or non-optimal antibiotic chemotherapy can lead to corneal perforation and rapid sight loss. In this study, we tested the ... -
Mimicking the intestinal host–pathogen interactions in a 3D In vitro model: The role of the mucus layer
García-Díaz, Maria; Cendra Gascón, María del Mar; Alonso Roman, Raquel; Urdániz, María; Torrents Serra, Eduard; Martínez, Elena (Multidisciplinary Digital Publishing Institute (MDPI), 2022-07-26)
Article
Accés obertThe intestinal mucus lines the luminal surface of the intestinal epithelium. This mucus is a dynamic semipermeable barrier and one of the first-line defense mechanisms against the outside environment, protecting the body ... -
Morphological and cytokine profiles as key parameters to distinguish between Gram-negative and Gram-positive bacterial keratitis
Konstantopoulos, Aris; Cendra Gascón, María del Mar; Tsatsos, Michael; Elabiary, Mariam; Christodoulides, Myron; Hossain, Parwez (Nature, 2020-12)
Article
Accés obertBacterial keratitis (BK) is an ocular disorder associated with poor visual prognosis. Quantification of the associated inflammatory response may provide insight into the pathogenesis of BK and guide treatment options. In ... -
Nano-engineering stable contact-based antimicrobials: Chemistry at the interface between nano-gold and bacteria
Vukomanovic, Marija; Cendra Gascón, María del Mar; Baelo, Aida; Torrents Serra, Eduard (Elsevier, 2021-12)
Article
Accés obertContact-based antimicrobials, as antibiotic-free technologies that use non-specific interactions with bacterial cells to exert antimicrobial activity, are a prospective solution in fighting the global issue of bacterial ... -
Optimal environmental and culture conditions allow the in vitro coexistence of Pseudomonas aeruginosa and Staphylococcus aureus in stable biofilms
Cendra Gascón, María del Mar; Torrents Serra, Eduard; Blanco Cabra, Núria; Pedraz, Lucas (Nature, 2019-12)
Article
Accés obertthe coexistence between species that occurs in some infections remains hard to achieve in vitro since bacterial fitness differences eventually lead to a single organism dominating the mixed culture. Pseudomonas aeruginosa ... -
Pseudomonas aeruginosa biofilms and their partners in crime
Cendra Gascón, María del Mar; Torrents Serra, Eduard (2021-07)
Article
Accés obertPseudomonas aeruginosa biofilms and the capacity of the bacterium to coexist and interact with a broad range of microorganisms have a substantial clinical impact. This review focuses on the main traits of P. aeruginosa ... -
Pseudomonas aeruginosa biofilms and their partners in crime
Cendra Gascón, María del Mar; Torrents Serra, Eduard (2021)
Comunicació de congrés
Accés obertThe ability of Pseudomonas aeruginosa to colonize medical devices and human tissues while growing in resistant communities called biofilms is a worldwide public health concern. P. aeruginosa biofilms have increased ... -
Pseudomonas aeruginosa host-pathogen interactions in human corneal infection models
Cendra Gascón, María del Mar; Elsahn, Ahmad; Humbert, Maria Victoria; Christodoulides, Myron; Dua, Harminder; Hossain, Parwez (Elsevier BV, 2020-06)
Article
Accés obertIn the whole tissue model (WTM), donor buttons were infected with PAO1 by scoring and intrastromal in-jection. Tissue was examined after 3, 9 and 24 h post challenge by transmission electron microscopy (TEM) andscanning ... -
Signaling mediated by toll-like receptor 5 sensing of pseudomonas aeruginosa Flagellin Influences IL-1ß and IL-18 production by primary fibroblasts derived from the human cornea
Cendra Gascón, María del Mar; Christodoulides, Myron; Hossain, Parwez (2017-04-19)
Article
Accés obertPseudomonas aeruginosa is the principal cause of bacterial keratitis worldwide and overstimulation of the innate immune system by this organism is believed to contribute significantly to sight loss. In the current study, ... -
Utility of Galleria mellonella larvae for evaluating nanoparticle toxicology
Moya Andérico, Laura; Cendra Gascón, María del Mar; Vokomanovic, Marija; Torrents Serra, Eduard; Segura Feliu, Miriam; del Río Fernández, José A.; Gil Fernández, Vanesa (2021-03)
Article
Accés obertThe use of nanoparticles in consumer products is currently on the rise, so it is important to have reliable methods to predict any associated toxicity effects. Traditional in vitro assays fail to mimic true physiological ...