Now showing items 1-9 of 9

    • A note on the Ecogen language built-in random deviate generators 

      Ocaña Rebull, Jordi; Ruiz de Villa Jubany, Ma. Carmen; Alonso, Guillem (Universitat Politècnica de Barcelona. Centre de Càlcul, 1986-09)
      Article
      Open Access
      The standard ECOGEN (a simulation language based on Pascal) random deviate generators are described. For every one of them, a short usage note and a description of the algorithm and underlying theory is presented. This ...
    • An iterative method to protect the type I error rate in bioequivalence studies under two-stage adaptive 2×2 crossover designs 

      Molins Lleonart, Eduard; Labes, Detlew; Schütz, Helmut; Cobo Valeri, Erik; Ocaña Rebull, Jordi (2021-01)
      Article
      Restricted access - publisher's policy
      Bioequivalence studies are the pivotal clinical trials submitted to regulatory agen- cies to support the marketing applications of generic drug products. Average bioequivalence (ABE) is used to determine whether the mean ...
    • Generación de un sistema bivariante con marginales dadas y estimación de su parámetro de dependencia 

      Ocaña Rebull, Jordi; Cuadras, C.M. (Carlos Maria) (Universitat Politècnica de Barcelona. Centre de Càlcul, 1987)
      Article
      Open Access
      En este trabajo se proponen dos posibles estimadores del parámetro de dependencia de una familia de distribuciones bivariantes con marginales dadas y se realiza un estudio de Monte Garlo de sus respectivos sesgo y eficiencia, ...
    • Modeling a Chilean Hospital using specification and description language 

      Leiva Olmos, Jorge; Fonseca Casas, Pau; Ocaña Rebull, Jordi (IGI Global, 2013-07)
      Part of book or chapter of book
      Restricted access - publisher's policy
      In this chapter, the authors present a formal model of the Anesthesia Unit and Surgical Wards (UAPQ) of a Chilean hospital. The objective was to document and to understand its operation, to assist hospital management and ...
    • On equivalence and bioequivalence testing 

      Ocaña Rebull, Jordi; Sánchez Olavarría, María Pilar; Sánchez, Alex; Carrasco Jordan, Josep Lluís (Institut d'Estadística de Catalunya, 2008)
      Article
      Open Access
      Equivalence testing is the natural approach to many statistical problems. First, its main application, bioequivalence testing, is reviewed. The basic concepts of bioequivalence testing (2×2 crossover designs, TOST, ...
    • The Ecogen language for genetic simulation 

      Ocaña Rebull, Jordi (Universitat Politècnica de Barcelona. Centre de Càlcul, 1985-03)
      Article
      Open Access
      This paper tries to show, in a condensed form, the main features of ECOGEN, an event-scheduling simulation language oriented to the Population Genetics. It is based on the Pascal Language.
    • The Simulation and Computational Statistics Research Group 

      Ocaña Rebull, Jordi (Institut d'estadística de Catalunya, 2002)
      Article
      Open Access
      Ressenya sobre la recerca actual en estadística a Catalunya: resultats del grup d'investigació català "The Simulation and Computational Statistics Research Group"
    • Two-stage designs versus European scaled average designs in bioequivalence studies for highly variable drugs: which to choose? 

      Molins Lleonart, Eduard; Cobo Valeri, Erik; Ocaña Rebull, Jordi (2017-12)
      Article
      Open Access
      The usual approach to determine bioequivalence for highly variable drugs is scaled average bioequivalence, which is based on expanding the limits as a function of the within-subject variability in the reference formulation. ...
    • Un model de competició amb selecció dependent de les freqüències i de la densitat 

      Ocaña Rebull, Jordi (Universitat Politècnica de Barcelona. Centre de Càlcul, 1982-12)
      Article
      Open Access
      En este trabajo se plantea un modelo general de competencia entre los individuos preadultos de una población y se determina la expresión de la eficacia biológica de todos los genotipos posibles, es decir, la probabilidad ...