Exploració per autor "Loza Álvarez, Pablo"

Ara es mostren els items 1-20 de 29

    • 3D-3-culture: A tool to unveil macrophage plasticity in the tumour microenvironment 

      Rebelo, Sofia P.; Martins, Tatiana R.; Estrada, Marta F.; Loza Álvarez, Pablo; Harrer, Nathalie; Alves, Paula M.; Cabeçadas, Jose; Gualda Manzano, Emilio José; Sommergruber, Wolfgang; Brito, Catarina (2018-05)
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      The tumour microenvironment (TME) shapes disease progression and influences therapeutic response.Most aggressive solid tumours have high levels of myeloid cell infiltration, namely tumour associatedmacrophages (TAM). ...

    • A novel culture method that sustains ERa signaling in human breast cancer tissue microstructures 

      Gualda Manzano, Emilio José; Furtado de Oliveira e Silva, Fernanda; Loza Álvarez, Pablo; Cartaxo, Ana Luisa; Estrada, Marta F.; Domenici, Giacomo; Sflomos, George; Brisken, Cathrin; Brito, Catarian (2020-12)
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      Breast cancer (BC) is the most commonly diagnosedcancer among women worldwide [1]. It is a heteroge-neous disease with distinct biological features and clin-ical outcomes. Almost 75% of diagnosed BC expressestrogen ...

    • Analysis of intracellular protein dynamics in living zebrafish embryos using light-sheet fluorescence single-molecule microscopy 

      Bernardello, Matteo; Gualda Manzano, Emilio José; Castro Olvera, Gustavo; Loza Álvarez, Pablo (2021-10-01)
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      Single-molecule microscopy techniques have emerged as useful tools to image individual molecules and analyze their dynamics inside cells, but their application has mostly been restricted to cell cultures. Here, a light-sheet ...

    • Autofluorescence of stingray skeletal cartilage: hyperspectral imaging as a tool for histological characterization 

      de Juan, Ana; Dean, Mason; Gualda Manzano, Emilio José; Marsal, Maria; Loza Álvarez, Pablo; Chaumel, Júlia; Gómez Sánchez, Adrián; Blumer, Michael (Springer Science and Business Media LLC, 2021-12)
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      Tessellated cartilage is a distinctive composite tissue forming the bulk of the skeleton of cartilaginous fishes (e.g. sharks and rays), built from unmineralized cartilage covered at the surface by a thin layer of mineralized ...

    • Bacillus firmus strain I-1582, a nematode antagonist by itself and through the plant 

      Ghahremani, Zahra; Escudero Benito, Nuria; Beltran Anadón, Daniel; Saus Martínez, Ester; Cunquero, Marina; Andilla, Jordi; Loza Álvarez, Pablo; Gabaldón Estevan, Toni; Sorribas Royo, Francisco Javier (2020-08-10)
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      Bacillus firmus I-1582 is approved in Europe for the management of Meloidogyne on vegetable crops. However, little information about its modes of action and temperature requirements is available, despite the effect of ...

    • Café científico 

      Vilaseca Ricart, Meritxell; Loza Álvarez, Pablo; Malet Munté, Roger (2021-09-14)
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      Com a part de les activitats del'acte central a nivell nacional del Dia Internacional de la Llum 2021, la biblioteca del Campus de Terrassa de la Universitat Politècnica de Catalunya (UPC) i l'Área Joven de la Sociedad ...

    • Compact ultrafast semiconductor disk laser: targeting GFP based nonlinear applications in living organisms 

      Loza Álvarez, Pablo; Artigas García, David; Santos, Susana I.C.O.; Aviles Espinosa, Rodrigo; Filippidis, George; Hamilton, Craig; Malcolm, Graeme; Weingarten, Kurt J.; Südmeyer, Thomas; Barbarin, Yohan; Keller, Ursula (2011-03-01)
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      Accés restringit per política de l'editorial
      We present a portable ultrafast Semiconductor Disk Laser (SDL) (or vertical extended cavity surface emitting laser—VECSELs), to be used for nonlinear microscopy. The SDL is modelocked using a quantum-dot semiconductor ...

    • Crop rotation with Meloidogyne-resistant germplasm is useful to manage and revert the (a)virulent populations of Mi1.2 gene and reduce yield losses 

      Fullana Pons, Aïda Magdalena; Expósito Creo, Alejandro; Cunquero, Marina; Loza Álvarez, Pablo; Giné Blasco, Ariadna; Sorribas Royo, Francisco Javier (Frontiers Media SA, 2023-03-15)
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      A rotation sequence of ungrafted and grafted tomato-melon-pepper- watermelon on resistant rootstocks ‘Brigeor’, Cucumis metuliferus, ‘Oscos’ and Citrullus amarus, respectively, was carried out in a plastic greenhouse, ...

    • Decoupled illumination detection in light sheet microscopy for fast volumetric imaging 

      OLARTE, Omar Eduardo; Andilla, Jordi; Artigas García, David; Loza Álvarez, Pablo (Optical Society of American (OSA), 2015-08-04)
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      Accés restringit per política de l'editorial
      Current microscopy demands the visualization of large threedimensional samples with increased sensitivity, higher resolution, and faster speed. Several imaging techniques based on widefield, point-scanning, and light-sheet ...

    • Deficiency of the ywhaz gene, involved in neurodevelopmental disorders, alters brain activity and behaviour in zebrafish 

      Antón Galindo, Ester; Dalla Vecchia, Luisa Felix; Gómez Orlandi, Javier; Castro Olvera, Gustavo; Guasch Piqueras, Marc; Arenas Sola, Concepción; García Fernandez, Jordi; Gualda Manzano, Emilio José; Herrera Úbeda, Carlos; Aguado Tomas, Fernando; Loza Álvarez, Pablo; Cormand, Bru; Norton, William H.J.; Fernández Castillo, Noelia; Young, Andrew M.J. (2022-05-02)
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      Genetic variants in YWHAZ contribute to psychiatric disorders such as autism spectrum disorder and schizophrenia, and have been related to an impaired neurodevelopment in humans and mice. Here, we have used zebrafish to ...

    • Depth aberrations characterization in linear and nonlinear microscopy schemes using a Shack-Hartmann wavefront sensor 

      Aviles Espinosa, Rodrigo; Andilla, Jordi; Porcar-Guezenec, Rafael; Levecq, Xavier; Artigas García, David; Loza Álvarez, Pablo (2012)
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      The performance of imaging devices such as linear and nonlinear microscopes (NLM) can be limited by the optical properties of the imaged sample. Such an important aspect has already been described using theoretical models ...

    • Effect of molecular organization on the image histograms of polarization SHG microscopy 

      Psilodimitrakopoulos, Sotiris; Amat Roldán, Iván; Loza Álvarez, Pablo; Artigas García, David (2012)
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      Based on its polarization dependency, second harmonic generation (PSHG) microscopy has been proven capable to structurally characterize molecular architectures in different biological samples. By exploiting this polarization ...

    • Estimating the helical pitch angle of amylopectin in starch using polarization second harmonic generation microscopy 

      Psilodimitrakopoulos, Sotiris; Amat Roldán, Iván; Loza Álvarez, Pablo; Artigas García, David (2010-08)
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      Accés restringit per política de l'editorial
      Starch granules are among the brightest natural second harmonic generation (SHG) converters. They basically consist of amylose and amylopectin molecules and the source of the SHG signal is still undetermined. In the ...

    • Fast monitoring of in-vivo conformational changes in myosin using single scan polarization- SHG microscopy 

      Psilodimitrakopoulos, Sotiris; Loza Álvarez, Pablo; Artigas García, David (2014-12-01)
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      Accés restringit per política de l'editorial
      Fast imaging of molecular changes under high-resolution and label-free conditions are essential for understanding in-vivo processes, however, current techniques are not able to monitor such changes in real time. Polarization ...

    • High-throughput live imaging using Light Sheet Microscopy 

      Gualda Manzano, Emilio José; Bernardello, Matteo; Marsal, Maria; Loza Álvarez, Pablo (2020)
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      We have developed a compact, multi-modal lightsheet microscope platform where different kind of experiments may be addressed with a single equipment. We will evaluate the performance of the Flexi-SPIM platform and its ...

    • Imaging amylopectin's order in starch using 3-dimensional polarization SHG 

      Psilodimitrakopoulos, Sotiris; Amat Roldán, Iván; Artigas García, David; Loza Álvarez, Pablo (International Society for Photo-Optical Instrumentation Engineers (SPIE), 2011)
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      In minimally destructive SHG biomedical imaging (high resolution optical slicing) is greatly desirable to extract the maximum of information from the light matter interaction. Here we develop a 3-D biophysical model and ...

    • Light-sheet fluorescence microscopy for the in vivo study of microtubule dynamics in the zebrafish embryo 

      Bernardello, Matteo; Marsal, Maria; Gualda Manzano, Emilio José; Loza Álvarez, Pablo (2021-10-01)
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      During its first hours of development, the zebrafish embryo presents a large microtubule array in the yolk region, essential for its development. Despite of its size and dynamic behavior, this network has been studied only ...

    • Measurement and correction of in vivo sample aberrations employing a nonlinear guide-star in two-photon excited fluorescence microscopy 

      Aviles Espinosa, Rodrigo; Andilla, Jordi; Porcar-Guezenec, Rafael; Olarte, Omar E.; Nieto, Marta; Levecq, Xavier; Artigas García, David; Loza Álvarez, Pablo (2011-11-01)
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      We demonstrate that sample induced aberrations can be measured in a nonlinear microscope. This uses the fact that two-photon excited fluorescence naturally produces a localized point source inside the sample: the nonlinear ...

    • Modelling biochemical gradients in vitro to control cell compartmentalization in a microengineered 3D model of the intestinal epithelium 

      Altay, Gizem; Gualda Manzano, Emilio José; Fernández-Majada, Vanesa; Batlle, Eduard; Loza Álvarez, Pablo; Martínez Fraiz, Elena; Abad Lázaro, Aina; Folch Eguren, Jordi; Insa Segarra, Claudia; Tosi, Sebastien (2022-09-07)
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      Accés restringit per política de l'editorial
      Gradients of signaling pathways within the intestinal stem cell (ISC) niche are instrumental for cellular compartmentalization and tissue function, yet how are they sensed by the epithelium is still not fully understood. ...

    • Modular multimodal platform for classical and high throughput light sheet microscopy 

      Bernardello, Matteo; Gualda Manzano, Emilio José; Loza Álvarez, Pablo (Nature, 2022-02-04)
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      Light-sheet fluorescence microscopy (LSFM) has become an important tool for biological and biomedical research. Although several illumination and detection strategies have been developed, the sample mounting still represents ...