Now showing items 1-6 of 6

    • Heparinization of beta tricalcium phosphate: osteo-immunomodulatory effects 

      Díez Escudero, Anna; Español Pons, Montserrat; Bonany Mariñosa, Mar; Persson, Cecilia; Ginebra Molins, Maria Pau (2018-03-07)
      Article
      Open Access
      Immune cells play a vital role in regulating bone dynamics. This has boosted the interest in developing biomaterials that can modulate both the immune and skeletal systems. In this study, calcium phosphates discs (i.e., ...
    • Hydrothermal processing of 3D-printed calcium phosphate scaffolds enhances bone formation in vivo: a comparison with biomimetic treatment 

      Raymond Llorens, Santiago; Bonany Mariñosa, Mar; Lehmann, Cyril; Thorel, Emilie; Benítez Iglesias, Raúl; Franch Serracanta, Jordi; Canal Barnils, Cristina; Ginebra Molins, Maria Pau (Elsevier, 2021-11-01)
      Article
      Open Access
      Covenantee:   Mimetis Biomaterials / Institut de Recerca Sant Joan de Déu / Universitat Autònoma de Barcelona / Universitat de Barcelona. Departament de Genètica, Microbiologia i Estadística / Institut de Bioenginyeria de Catalunya
      Hydrothermal (H) processes accelerate the hydrolysis reaction of a-tricalcium phosphate (a-TCP) compared to the long-established biomimetic (B) treatments. They are of special interest for patient-specific 3D-printed bone ...
    • Hydroxyapatite nanoparticles-cell interaction: New approaches to disclose the fate of membrane-bound and internalised nanoparticles 

      Bonany Mariñosa, Mar; Pérez Berná, Ana Joaquina; Ducic, Tanja; Pereiro López, Eva; Martín Gómez, Helena; Mas Moruno, Carlos; van Rijt, Sabine; Zhao, Zhitong; Español Pons, Montserrat; Ginebra Molins, Maria Pau (Elsevier, 2022-11-01)
      Article
      Open Access
      Covenantee:   Sincrotró ALBA / Universiteit van Maastricht / Institut de Bioenginyeria de Catalunya / Nanyang Technological University
      Hydroxyapatite nanoparticles are popular tools in bone regeneration, but they have also been used for gene delivery and as anticancer drugs. Understanding their mechanism of action, particularly for the latter application, ...
    • Impact of biomimicry in the design of osteoinductive bone substitutes: nanoscale matters 

      Barba Serrahima, Albert; Díez Escudero, Anna; Español Pons, Montserrat; Bonany Mariñosa, Mar; Sadowska, Joanna Maria; Guillem Martí, Jordi; Ohman, Caroline; Persson, Cecilia; Manzanares, Maria Cristina; Franch, Jordi; Ginebra Molins, Maria Pau (2019-01-01)
      Article
      Open Access
      Covenantee:   Universitat Autònoma de Barcelona / Uppsala universitet / Universitat de Barcelona. Departament de Patologia i Terapèutica Experimental / Institut de Bioenginyeria de Catalunya
      Bone apatite consists of carbonated calcium-deficient hydroxyapatite (CDHA) nanocrystals. Biomimetic routes allow fabricating synthetic bone grafts that mimic biological apatite. In this work, we explored the role of two ...
    • Microsphere incorporation as a strategy to tune the biological performance of bioinks 

      Bonany Mariñosa, Mar; Mazo Barbara, Laura del; Español Pons, Montserrat; Ginebra Molins, Maria Pau (SAGE publishing, 2022-01-01)
      Article
      Open Access
      Covenantee:   Centre de Recerca en Enginyeria Biomedica (CREB) / Institut de Bioenginyeria de Catalunya
      Although alginate is widely used as a matrix in the formulation of cell-laden inks, this polymer often requires laborious processing strategies due to its lack of cell adhesion moieties. The main objective of the present ...
    • Osteoinduction by foamed and 3D-printed calcium phosphate scaffolds: effect of nanostructure and pore architecture 

      Barba Serrahima, Albert; Díez Escudero, Anna; Maazouz, Yassine; Rappe, K.; Español Pons, Montserrat; Montufar Jiménez, Edgar Benjamin; Bonany Mariñosa, Mar; Sadowska, Joanna Maria; Guillem Martí, Jordi; Ohman, Caroline; Persson, Cecilia; Manzanares, Maria Cristina; Franch Serracanta, Jordi; Ginebra Molins, Maria Pau (2017-12-06)
      Article
      Open Access
      Covenantee:   Universitat Autònoma de Barcelona. Departament de Medicina i Cirurgia Animal / Universitat de Barcelona. Departament de Patologia i Terapèutica Experimental
      Some biomaterials are osteoinductive, that is, they are able to trigger the osteogenic process by inducing the differentiation of mesenchymal stem cells to the osteogenic lineage. Although the underlying mechanism is still ...