Browsing by Author "Fraioli, Roberta"
Now showing items 1-11 of 11
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A novel peptide-based platform for the dual presentation of biologically-active peptide motifs on biomaterials
(2014-03-27)
Article
Restricted access - publisher's policyBiofunctionalization of metallic materials with cell adhesive molecules derived from the extracellular matrix is a feasible approach to improve cell–material interactions and enhance the biointegration of implant materials ... -
avß3- or a5ß1-Integrin-Selective Peptidomimetics for Surface Coating
(2016-06-13)
Article
Open Access
Covenantee: Technische Universität MünchenEngineering biomaterials with integrin-binding activity is a very powerful approach to promote cell adhesion, modulate cell behavior, and induce specific biological responses at the surface level. The aim of this Review ... -
Blocking methods to prevent non-specific adhesion of mesenchymal stem cells to titanium and evaluate the efficiency of surface functionalization: albumin vs poly(ethylene glycol) coating
(Sociedad Ibérica de Biomecánica y Biomateriales, 2014)
Article
Open AccessSurface modification of biocompatible materials with biologically-active molecules is a well-known strategy to enhance the osteointegration of implantable devices. In order to evaluate the efficiency of these treatments, ... -
Co-localization of RGD and PHSRN peptides on titanium to guide stem cell behaviour and enhance Implant osteointegration
(2015)
Conference lecture
Open Access -
Control of stem cell response and bone growth on biomaterials by fully non-peptidic integrin selective ligands
(Royal Society of Chemistry (RSC), 2019-04-01)
Article
Open Access
Covenantee: Technische Universität München / Universitat Internacional de Catalunya / Tan'guk Taehakkyo / Institut de Bioenginyeria de CatalunyaIn this communication we report that anchoring avß3 or a5ß1 integrin-selective RGD peptidomimetics to titanium efficiently tunes mesenchymal stem cell response in vitro and bone growth in rat calvarial defects. Our results ... -
Functionalization of titanium with integrin-selective ligands for orthopedic and dental applications
(Universitat Politècnica de Catalunya, 2016-11-14)
Doctoral thesis
Open AccessDespite being biocompatible and with adequate mechanical properties for application as a bone replacement material, titanium lacks osteoinductive capacity, i.e. it supports new bone growth on its surface but does not foster ... -
Mimicking bone extracellular matrix: Integrin-binding peptidomimetics enhance osteoblast-like cells adhesion, proliferation, and differentiation on titanium
(2015-04-01)
Article
Open Access
Covenantee: Technische Universität MünchenInteraction between the surface of implants and biological tissues is a key aspect of biomaterials research. Apart from fulfilling the non-toxicity and structural requirements, synthetic materials are asked to direct cell ... -
Novel peptide-based platform for the dual presentation of biologically active peptide motifs on biomaterials
(2014-05-14)
Article
Restricted access - publisher's policyBiofunctionalization of metallic materials with cell adhesive molecules derived from the extracellular matrix is a feasible approach to improve cell-material interactions and enhance the biointegration of implant materials ... -
Novel peptide-based strategies to install osteointegrative properties on metallic biomaterials
(2015)
Conference lecture
Open Access
Covenantee: Technische Universität München -
Surface guidance of stem cell behavior: Chemically tailored co-presentation of integrin-binding peptides stimulates osteogenic differentiation in vitro and bone formation in vivo
(2016-10-01)
Article
Open Access
Covenantee: Tan'guk TaehakkyoSurface modification stands out as a versatile technique to create instructive biomaterials that are able to actively direct stem cell fate. Chemical functionalization of titanium has been used in this work to stimulate ... -
Towards the cell-instructive bactericidal substrate: exploring the combination of nanotopographical features and integrin selective synthetic ligands
(Macmillan Publishers, 2017-11-27)
Article
Open Access
Covenantee: Technische Universität München / University of Bristol. Bristol Dental SchoolEngineering the interface between biomaterials and tissues is important to increase implant lifetime and avoid failures and revision surgeries. Permanent devices should enhance attachment and differentiation of stem cells, ...
