Now showing items 1-20 of 55

    • A 3D finite element model of ventral furrow invagination in the Drosophila melanogaster embryo 

      Conte, Vito; Muñoz Romero, José; Miodownik, Mark (2008-04)
      Article
      Open Access
      The paper describes a mechanical model of epithelial tissue development in Drosophila embryos to investigate a buckling phenomenon called invagination. The finite element method is used to model this ventral furrow formation ...
    • A biomechanical analysis of ventral furrow formation in the Drosophila melanogaster embryo 

      Conte, Vito; Ulrich, Florian; Baum, Buzz; Muñoz Romero, José; Veldhuis, Jim; Brodland, Wayne; Miodownik, M. (2012-03-28)
      Article
      Open Access
      The article provides a biomechanical analysis of ventral furrow formation in the Drosophila melanogaster embryo. Ventral furrow formation is the first large-scale morphogenetic movement in the fly embryo. It involves ...
    • A deformation gradient decomposition method for the analysis of the mechanics of morphogenesis 

      Muñoz Romero, José; Barrett, K.; Miodownik, M. (2007-06)
      Article
      Open Access
      A new finite element model is proposed for the analysis of the mechanical aspects of morphogenesis and tested on the biologically well studied gastrulation phenomenon, in particular ventral furrow invagination of the ...
    • A note on upper bound formulations in limit analysis 

      Muñoz Romero, José; Huerta, Antonio; Bonet Carbonell, Javier; Peraire, Jaume (John Wiley & Sons, 2012-08-24)
      Article
      Restricted access - publisher's policy
      In this paper we study some recent formulations for the computation of upper bounds in limit analysis. We show that a previous formulation presented by the authors does not guarantee the strictness of the upper bound, ...
    • A truss element for modelling reversible softening in living tissues 

      Muñoz Romero, José; Conte, Vito; Asadipour, Nina; Miodownik, M. (2013-04-01)
      Article
      Open Access
      We resort to non-linear viscoelasticity to develop a truss element able to model reversible softening in lung epithelial tissues undergoing transient stretch. Such a Maxwell truss element is built by resorting to a ...
    • AAR-based decomposition algorithm for non-linear convex optimisation 

      Rabiei, Syednima; Muñoz Romero, José (2014)
      Conference lecture
      Open Access
    • AAR-based decomposition algorithm for non-linear convex optimisation 

      Rabiei, Syednima; Muñoz Romero, José (2015)
      Article
      Open Access
      n this paper we present a method for decomposing a class of convex nonlinear programmes which are frequently encountered in engineering plastic analysis. These problems have second-order conic memberships constraints and ...
    • AAR-based decomposition method for limit analysis 

      Rabiei, Nima; Muñoz Romero, José (Centre Internacional de Mètodes Numèrics en Enginyeria (CIMNE), 2014)
      Conference lecture
      Open Access
    • AAR-based decomposition method for lower bound limit analysis 

      Muñoz Romero, José; Rabiei, Nima (2015-12-01)
      Article
      Open Access
      Despite the recent progress in optimisation techniques, finite-element stability analysis of realistic three-dimensional problems is still hampered by the size of the resulting optimisation problem. Current solvers may ...
    • AAR-based decomposition method for lower-bound limit analysis 

      Muñoz Romero, José; Rabiei, Syednima (2015)
      Article
      Open Access
      Despite the recent progress in optimisation techniques, finite-element stability analysis of realistic three-dimensional problems is still hampered by the size of the resulting optimisation problem. Current solvers may ...
    • Cell-centered truss model for the analysis of cell rheology and remodelling 

      Muñoz Romero, José; Asadipour, Nina; Albo, Santiago (2013)
      Conference lecture
      Open Access
      Soft active tissues exhibit softening, hardening, and reversible fluidisation [14]. The result of these non-linear behaviour is due to multiple processes taking part at di erent scales: active protein motors that actuate ...
    • Cell-centred model for non-linear tissue rheology and active remodelling 

      Asadipour, Nina; Mosaffa, Payman; Muñoz Romero, José (Centre Internacional de Mètodes Numèrics en Enginyeria (CIMNE), 2014)
      Conference report
      Restricted access - publisher's policy
      Soft active tissues exhibit softening, hardening, and reversible fluidisation. The result of these non-linear behaviour is due to multiple processes taking part at different scales: active protein motors that actuate at ...
    • Cell-centred model for the simulation of curved cellular monolayers 

      Mosaffa, Payman; Asadipour, Nina; Millán, Raúl Daniel; Rodríguez Ferran, Antonio; Muñoz Romero, José (2015)
      Article
      Open Access
      This paper presents a cell-centred model for the simulation of planar and curved multicellular soft tissues. We propose a computational model that includes stress relaxation due to cell reorganisation (intercellular ...
    • Collective cell durotaxis emerges from long-range intercellular force transmission 

      Sunyer, Raimon; Conte, Vito; Escribano, Jorge; Elosegui Artola, Alberto; Labernadie, Anna; Valon, Leo; Navajas Navarro, Daniel; Garcia Aznar, José Manuel; Muñoz Romero, José; Trepat, Xavier (2016-09-09)
      Article
      Open Access
      The ability of cells to follow gradients of extracellular matrix stiffness—durotaxis—has been implicated in development, fibrosis, and cancer. Here, we found multicellular clusters that exhibited durotaxis even if isolated ...
    • Computation of bounds for anchor problems in limit analysis and decomposition techniques 

      Muñoz Romero, José; Rabiei, Syednima; Lyamin, Andrei; Huerta, Antonio (Springer, 2013-07-15)
      Part of book or chapter of book
      Open Access
      Numerical techniques for the computation of strict bounds in limit analyses have been developed for more than thirty years. The efficiency of these techniques have been substantially improved in the last ten years, and ...
    • Computation of forces from deformed visco-elastic biological tissues 

      Muñoz Romero, José; Amat Olóndriz, David; Conte, Vito (2018-04-01)
      Article
      Open Access
      We present a least-squares based inverse analysis of visco-elastic biological tissues. The proposed method computes the set of contractile forces (dipoles) at the cell boundaries that induce the observed and quantified ...
    • Computational limit analysis for anchors and retaining walls 

      Muñoz Romero, José; Lyamin, Andrei V.; Huerta, Antonio (Universitat Politècnica de Catalunya. Escola Tècnica Superior de Camins Canals i Ports de Barcelona, 2011-11-15)
      Conference lecture
      Open Access
      The computation of the bearing capacity of engineering structures commonly relays on results obtained for simple academic examples. Recent developments in computational limit analysis have allowed engineers to compute ...
    • Computational modeling of epithelial wound healing: Short and long term chemo-mechanical mechanisms 

      Roldan, Lisandro; Muñoz Romero, José; Sáez Viñas, Pablo (2019-06-15)
      Article
      Restricted access - publisher's policy
      During the lifetime of all living multicellular organisms, wounds in their tissues are frequently observed. Thecapability of closing those gaps is fundamental for a healthy development. If done deficiently, many diseasesmay ...
    • Conserving time-integration of beams under contact constrains using B-Spline interpolation 

      Sibileau, Alberto; Muñoz Romero, José (2011)
      Conference report
      Open Access
      The design of energy-momentum algorithms for geometrically exact beams has been achieved more than 15 years ago. However, many of the desired conserivng propeties do not carry over into constrained systems such as beams ...
    • Control of cell-cell forces and collective cell dynamics by the intercellular adhesome 

      Bazellieres, Elsa; Conte, Vito; Elosegui Artola, Alberto; Serra-Picamal, Xavier; Bintanel Morcillo, Maria; Roca Cusachs, Pere; Muñoz Romero, José; Sales Pardo, Marta; Guimerà, Roger; Trepat Guixer, Xavier (2015-04-01)
      Article
      Open Access
      Dynamics of epithelial tissues determine key processes in development, tissue healing and cancer invasion. These processes are critically influenced by cell-cell adhesion forces. However, the identity of the proteins that ...