Browsing by Author "Roldán Molina, Mónica"
Now showing items 1-10 of 10
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A Convolutional Neural Network for the automatic diagnosis of collagen VI-related muscular dystrophies
(2019-12-01)
Article
Open AccessThe development of machine learning systems for the diagnosis of rare diseases is challenging, mainly due to the lack of data to study them. This paper surmounts this obstacle and presents the first Computer-Aided Diagnosis ... -
Estudio espectroscópico de glóbulos rojos mediante microscopía confocal en pacientes con talasemia
(Universidad de Jaén, 2019)
Conference lecture
Restricted access - publisher's policy -
Estudio espectroscópico de glóbulos rojos mediante microscopía confocal en pacientes con talasemia: resultados preliminares
(Arán Ediciones, 2019)
Conference lecture
Restricted access - publisher's policy -
Evaluación de la microscopía confocal como herramienta de diagnóstico en enfermedades de los glóbulos rojos
(Universitat Politècnica de Catalunya, 2022-07-01)
Conference lecture
Open AccessLa esferocitosis hereditaria (EH) provoca mutaciones en las proteínas de la membrana de los glóbulos rojos (GRs) que hacen que las células se deformen y se vuelvan demasiado rígidas para poder viajar a través de los vasos ... -
Evaluation of confocal microscopy as a diagnosis tool on red blood cell diseases
(2021)
Conference report
Restricted access - publisher's policyIn hereditary spherocytosis, mutations in red blood cell membrane proteins result in an overly rigid, misshapen cell whose deformability when traveling through the blood vessels is lost, causing severe anemia and splenomegaly, ... -
Innovative computerized dystrophin quantification method based on spectral confocal microscopy
(Multidisciplinary Digital Publishing Institute (MDPI), 2023-03-28)
Article
Open AccessSeveral clinical trials are working on drug development for Duchenne and Becker muscular dystrophy (DMD and BMD) treatment, and, since the expected increase in dystrophin is relatively subtle, high-sensitivity quantification ... -
Membrane protein detection and morphological analysis of red blood cells in hereditary spherocytosis by confocal laser scanning microscopy
(2023-04)
Article
Open AccessIn hereditary spherocytosis (HS), genetic mutations in the cell membrane and cytoskeleton proteins cause structural defects in red blood cells (RBCs). As a result, cells are rigid and misshapen, usually with a characteristic ... -
Multispectral imaging of healthy and diseased red blood cells using confocal microscopy
(2021-05-14)
Audiovisual
Open AccessRed blood cells (RBCs) alterations can cause very severe blood diseases. In thalassemia, the production of hemoglobin polypeptide chains is unbalanced. This causes no symptoms or small blood count alterations in patients ... -
Multispectral imaging of healthy and diseased red blood cells using confocal microscopy
(2021-05-13)
Conference lecture
Open Access -
Self-assembling as regular nanoparticles dramatically minimizes photobleaching of tumour-targeted GFP
(Elsevier, 2020-02-03)
Article
Open AccessFluorescent proteins are useful imaging and theranostic agents, but their potential superiority over alternative dyes is weakened by substantial photobleaching under irradiation. Enhancing protein photostability has been ...
