Browsing by Author "Pérez Rafael, Silvia"
Now showing items 1-16 of 16
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Antibacterial polyurethane foams with incorporated lignin-capped silver nanoparticles for chronic wound treatment
Morena Gatius, Ángela Gala; Ivanova, Kristina Dimitrova; Pérez Rafael, Silvia; Sánchez Soto, Miguel; Tzanov, Tzanko; Stefanov, Ivaylo (2020-02-26)
Article
Open AccessLignin-capped silver nanoparticles were incorporated in situ into polyurethane foams during their polymerization to obtain multifunctional materials suitable for chronic wound dressing. Lignin with increased phenolic ... -
Antimicrobial and antifouling hyaluronic acid-cobalt nanogel coatings built sonochemically on contact lenses
Ferreres Cabanes, Guillem; Pérez Rafael, Silvia; Guaus Guerrero, Ester; Palacios Bonilla, Òscar; Ivanov, Ivan; Torrent Burgués, Juan; Tzanov, Tzanko (2024-12)
Article
Open AccessThe wearing of contact lenses (CLs) may cause bacterial infections, leading in turn to more serious complications and ultimately vision impairment. In this scenario, the first step is the adhesion of tear proteins, which ... -
Antimicrobial lightweight materials and components
Morena Gatius, Ángela Gala; Ferreres Cabanes, Guillem; Ivanova, Kristina Dimitrova; Pérez Rafael, Silvia; Tzanov, Tzanko (Elsevier, 2020-12-02)
Part of book or chapter of book
Restricted access - publisher's policyLightweight materials and components have gained remarkable scientific and technological importance in the recent times as the main drivers of innovation. They are finding widespread use across all industry sectors to ... -
Cobalt-phenolic nanoparticles-driven self-assembly of hyaluronic acid hydrogels providing a multifactorial approach for chronic wound management
Ferreres Cabanes, Guillem; Pérez Rafael, Silvia; Palacios Bonilla, Òscar; Todorova, Katerina; Hinojosa-Caballero, Dolores; Torrent Burgués, Juan; Tzanov, Tzanko (2024-06-13)
Article
Open AccessChronic wounds are persistent non-healing lesions whose complex management is due to the interplay of multiple factors promoting chronicity, such as oxidative stress, overexpressed enzyme activities impeding the tissue ... -
Continuous sonochemical nanotransformation of lignin - process design and control
Pérez Rafael, Silvia; Ferreres Cabanes, Guillem; Kessler, Rudolf; Kessler, Waltraud; Blair González, Jeniffer; Rathee, Garima; Morena, Angela Gala; Tzanov, Tzanko (2023-06)
Article
Open AccessAs the most abundant renewable aromatic polymer on the planet, lignin is gaining growing interest in replacing petroleum-based chemicals and products. However, only <5 % of industrial lignin waste is revalorized in its ... -
Dual electro-/pH-responsive nanoparticle/hydrogel system for controlled delivery of anticancer peptide
Resina, Maria Leonor Matos; Esteves, Teresa; Pérez Rafael, Silvia; Hernández García, José Ignacio; Castelo Ferreira, Frederico; Tzanov, Tzanko; Bonardd, Sebastián; Díaz Díaz, David; Pérez Madrigal, Maria del Mar; Alemán Llansó, Carlos (Elsevier, 2024-06)
Article
Restricted access - publisher's policyAn electro-chemo-responsive carrier has been engineered for the controlled release of a highly hydrophilic anticancer peptide, CR(NMe)EKA (Cys-Arg- N-methyl-Glu-Lys-Ala). Remotely controlled on demand release of CR(NMe)EKA, ... -
Enzymatically built nanoenabled antimicrobial coating on urinary catheters
Puertas Segura, Antonio Jesús; Morena Gatius, Ángela Gala; Pérez Rafael, Silvia; Ivanova, Kristina Dimitrova; Ivanov, Ivan; Todorova, Katerina; Dimitrov, Petar; Ciardeli, Gianluca; Tzanov, Tzanko (2024-07-23)
Article
Open AccessCatheter-associated urinary tract infections represent a major share of nosocomial infections, and are associated with longer periods of hospitalization and a huge financial burden. Currently, there are only a handful of ... -
Hyaluronic acid derivative molecular weight-dependent synthesis and antimicrobial effect of hybrid silver nanoparticles
Ferreres Cabanes, Guillem; Pérez Rafael, Silvia; Torrent Burgués, Juan; Tzanov, Tzanko (2021-12-14)
Article
Open AccessSilver nanoparticles (Ag NPs) appeared as promising antimicrobial candidates to face the development of antibiotic resistance. Although reported as toxic towards mammalian cells, their combination with biomolecules have ... -
Influence of enzymatically hydrophobized hemp protein on morphology and mechanical properties of bio-based polyurethane and epoxy foams
Ferreres Cabanes, Guillem; Pérez Rafael, Silvia; Morena Gatius, Ángela Gala; Tzanov, Tzanko; Gryshchuk, Liudmyla (Multidisciplinary Digital Publishing Institute (MDPI), 2023-08-31)
Article
Open AccessBiomass fillers offer the possibility to modify the mechanical properties of foams, increasing their cost-effectiveness and reducing their carbon footprint. In this study, bio-based PU (soft, open cells for the automotive ... -
Lignin-based nanoparticles as both structural and active elements in self-assembling and self-healing multifunctional hydrogels for chronic wound management
Morena Gatius, Ángela Gala; Pérez Rafael, Silvia; Tzanov, Tzanko (Multidisciplinary Digital Publishing Institute (MDPI), 2022-11-30)
Article
Open AccessEfficient wound healing is feasible when the dressing materials simultaneously target multiple factors causing wound chronicity, such as deleterious proteolytic and oxidative enzymes and bacterial infection. Herein, entirely ... -
Multifunctional enzymatically generated hydrogels for chronic wound application
Stefanov, Ivaylo; Hoyo Pérez, Javier; Cailloux, Jonathan; Santana Pérez, Orlando Onofre; Tzanov, Tzanko; Pérez Rafael, Silvia; Hinojosa-Caballero, Dolores (2017-04-19)
Article
Open AccessThe healing of chronic wounds requires intensive medical intervention at huge healthcare costs. Dressing materials should consider the multifactorial nature of these wounds comprising deleterious proteolytic and oxidative ... -
Nano-formulation endows quorum quenching enzyme-antibiotic hybrids with improved antibacterial and antibiofilm activities against pseudomonas aeruginosa
Ivanova, Kristina Dimitrova; Ivanova, Aleksandra Asenova; Hoyo, Javier; Pérez Rafael, Silvia; Tzanov, Tzanko (2022-07-11)
Article
Open AccessThe emergence of antibiotic resistant bacteria coupled with the shortage of efficient antibacterials is one of the most serious unresolved problems for modern medicine. In this study, the nano-hybridization of the clinically ... -
Nanoparticle-driven self-assembling injectable hydrogels provide a multi-factorial approach for chronic wound treatment
Pérez Rafael, Silvia; Ivanova, Kristina Dimitrova; Stefanov, Ivaylo; Puiggalí Bellalta, Jordi; Valle Mendoza, Luis Javier del; Todorova, Katerina; Dimitrov, Petar; Hinojosa Caballero, Dolores; Tzanov, Tzanko (Elsevier, 2021-07-14)
Article
Open AccessChronic wounds represent a major health burden and drain on medical system. Efficient wound repair is only possible if the dressing materials target simultaneously multiple factors involved in wound chronicity, such as ... -
Nanotransformation of vancomycin overcomes the intrinsic resistance of Gram-negative bacteria
Ivanova, Kristina Dimitrova; Hoyo Pérez, Javier; Francesko, Antonio; Tzanov, Tzanko; Fernandes, Margarida M.; Pérez Rafael, Silvia (2017-04-10)
Article
Open AccessThe increased emergence of antibiotic-resistant bacteria is a growing public health concern, and although new drugs are constantly being sought, the pace of development is slow compared with the evolution and spread of ... -
New myeloperoxidase detection system based on enzyme-catalysed oxidative synthesis of a dye for paper-based diagnostic devices
Bassegoda Puigdomenech, Arnau; Ferreres Cabanes, Guillem; Pérez Rafael, Silvia; Hinojosa-Caballero, Dolores; Torrent Burgués, Juan; Tzanov, Tzanko (2018-10-21)
Article
Open AccessThe severity and cost of wound infections strongly demands for simple and fast methods for wound infection determination. Point-of-care testing devices play a crucial role in order to achieve a fast diagnosis and early ... -
Sono-enzymatically embedded antibacterial silver-lignin nanoparticles on cork filter material for water disinfection
Bermeo, Lizeth; Ivanova, Kristina Dimitrova; Pérez, Leonardo Martín; Forés, Eva; Pérez Rafael, Silvia; Casas-Zapata, Juan C. C.; Morató Farreras, Jordi; Tzanov, Tzanko (Multidisciplinary Digital Publishing Institute (MDPI), 2022-10-02)
Article
Open AccessProviding clean drinking water is a great challenge worldwide, especially for low-income countries where the access to safe water is limited. During the last decade, new biotechnological approaches have been explored to ...