Browsing by Author "Fernández González, Pol"
Now showing items 1-6 of 6
-
Effect of sodium valproate on the conformational stability of the visual G Protein-coupled receptor rhodopsin
(2021-05-19)
Article
Open AccessRhodopsin is the G protein-coupled receptor of rod photoreceptor cells that mediates vertebrate vision at low light intensities. Mutations in rhodopsin cause inherited retinal degenerative diseases such as retinitis ... -
Effect of trace metal Ions on the conformational stability of the visual photoreceptor rhodopsin
(Multidisciplinary Digital Publishing Institute (MDPI), 2023-07-01)
Article
Open AccessTrace metals are essential elements that play key roles in a number of biochemical processes governing human visual physiology in health and disease. Several trace metals, such as zinc, have been shown to play important ... -
New insights into the molecular mechanism of rhodopsin retinitis pigmentosa from the biochemical and functional characterization of G90V, Y102H and I307N mutations
(Springer Nature, 2022-01-01)
Article
Open AccessMutations in the photoreceptor protein rhodopsin are known as one of the leading causes of retinal degeneration in humans. Two rhodopsin mutations, Y102H and I307N, obtained in chemically mutagenized mice, are currently ... -
Novel ligands for the treatment of retinal degenerative diseases
(2023-05-17)
Conference lecture
Open Access -
Polyphenols and visual health: potential effects on degenerative retinal diseases
(2021-06-04)
Article
Open AccessDietary polyphenols are a group of natural compounds that have been proposed to have beneficial effects on human health. They were first known for their antioxidant properties, but several studies over the years have shown ... -
Retigabine increases the conformational stability of the visual photoreceptor rhodopsin
(2024-09)
Article
Open AccessRhodopsin is the key photoreceptor protein that mediates vision in low-light conditions. Mutations in rhodopsin are the cause of retinal degenerative diseases such as retinitis pigmentosa. Some of these mutations cause a ...
