Exploració per autor "Galván Femenía, Iván"

Ara es mostren els items 1-11 de 11

    • A Compositional Approach to Allele Sharing Analysis 

      Galván Femenía, Iván; Graffelman, Jan (Springer, 2016)
      Capítol de llibre
      Accés restringit per política de l'editorial
      Relatedness is of great interest in population-based genetic association studies. These studies search for genetic factors related to disease. Many statistical methods used in population-based genetic association studies ...

    • A likelihood ratio approach for identifying three-quarter siblings in genetic databases 

      Galván Femenía, Iván; Barceló Vidal, Carles; Sumoy, Lauro; Moreno Aguado, Victor Raul; de Cid, Rafael; Graffelman, Jan (2021-01-15)
      Article
      Accés obert
      The detection of family relationships in genetic databases is of interest in various scientific disciplines such as genetic epidemiology, population and conservation genetics, forensic science, and genealogical research. ...

    • A log-ratio biplot approach for exploring genetic relatedness based on identity by state 

      Graffelman, Jan; Galván Femenía, Iván; de Cid, Rafael; Barceló Vidal, Carles (2019-04-24)
      Article
      Accés obert
      The detection of cryptic relatedness in large population-based cohorts is of great importance in genome research. The usual approach for detecting closely related individuals is to plot allele sharing statistics, based on ...

    • Allele-Sharing analysis and relationship inference 

      Galván Femenía, Iván (Universitat Politècnica de Catalunya / Universitat de Barcelona / Universitat de Girona, 2014-06)
      Projecte Final de Màster Oficial
      Accés restringit per decisió de l'autor
      This master's thesis presents some techniques in statistical genetics to study family relationships. Two individuals can share 0, 1 or 2 alleles for any genetic marker. The larger the number of shared alleles between a ...

    • An application of the isometric log-ratio transformation in relatedness research 

      Graffelman, Jan; Galván Femenía, Iván (Springer, 2016)
      Capítol de llibre
      Accés restringit per política de l'editorial
      Abstract Genetic marker data contains information on the degree of relatedness of a pair of individuals. Relatedness investigations are usually based on the extent to which alleles of a pair of individuals match over a set ...

    • Assessment of kinship detection using RNA-seq data 

      Blay Magriñá, Natàlia; Casas, Eduard; Galván Femenía, Iván; Graffelman, Jan; de Cid, Rafael; Vavouri, Tanya (2019-12-02)
      Article
      Accés obert
      Analysis of RNA sequencing (RNA-seq) data from related individuals is widely used in clinical and molecular genetics studies. Prediction of kinship from RNA-seq data would be useful for confirming the expected relationships ...

    • GCAT|Panel, a comprehensive structural variant haplotype map of the Iberian population from high-coverage whole-genome sequencing 

      Valls Margarit, Jordi; Galván Femenía, Iván; Matías Sánchez, Daniel; Blay, Natalia; Puiggròs, Montserrat; Salvoro, Cecilia; Amela, Ramon; Torrents Arenales, David (Oxford University Press, 2022-03)
      Article
      Accés obert
      The combined analysis of haplotype panels with phenotype clinical cohorts is a common approach to explore the genetic architecture of human diseases. However, genetic studies are mainly based on single nucleotide variants ...

    • GCAT|Panel, a comprehensive structural variant haplotype map of the Iberian population from high-coverage whole-genome sequencing 

      Valls Margarit, Jordi; Galván Femenía, Iván; Matías Sánchez, Daniel; Blay, Natalia; Puiggròs, Montserrat; Salvoro, Cecilia; Amela, Ramon; Torrents, David (Oxford University Press, 2022-02)
      Article
      Accés obert
      The combined analysis of haplotype panels with phenotype clinical cohorts is a common approach to explore the genetic architecture of human diseases. However, genetic studies are mainly based on single nucleotide variants ...

    • Graphics for relatedness research 

      Galván Femenía, Iván; Graffelman, Jan; Barceló Vidal, Carles (Wiley, 2017-04-03)
      Article
      Accés obert
      Studies of relatedness have been crucial in molecular ecology over the last decades. Good evidence of this is the fact that studies of population structure, evolution of social behaviours, genetic diversity and quantitative ...

    • Multitrait genome association analysis identifies new susceptibility genes for human anthropometric variation in the GCAT cohort 

      Galván Femenía, Iván; Obón-Santacana, Mireia; Piñeyro, David; Guindo-Martinez, Marta; Duran, Xavier; Carreras, Anna; Pluvinet, Raquel; Velasco, Juan; Ramos, Laia; Aussó, Susanna; Puig, Lluis; Perucho, Manuel; Torrents, David; Moreno, Victor; Sumoy, Lauro; de Cid, Rafael (BMJ Publishing Group, 2018-08-30)
      Article
      Accés obert
      Background Heritability estimates have revealed an important contribution of SNP variants for most common traits; however, SNP analysis by single-trait genome-wide association studies (GWAS) has failed to uncover their ...

    • Pipeline design to identify key features and classify the chemotherapy response on lung cancer patients using large-scale genetic data 

      Valdés, María Gabriela; Galván Femenía, Iván; Ribas Ripoll, Vicent; Duran Albareda, Xavier; Yokota, Jun; Gavaldà Mestre, Ricard; Rafael-Palou, Xavier; de Cid, Rafael (2018-11-20)
      Article
      Accés obert
      Background: During the last decade, the interest to apply machine learning algorithms to genomic data has increased in many bioinformatics applications. Analyzing this type of data entails difficulties for managing ...