Now showing items 1-19 of 19

  • Accelerated hardening of nanotextured 3D-plotted self-setting calcium phosphate inks 

    Raymond Llorens, Santiago; Maazouz, Yassine; Montufar Jiménez, Edgar Benjamin; Perez, Roman A.; González Arcos, Borja; Konka, Joanna Magdalena; Ginebra Molins, Maria Pau (Elsevier, 2018-01-01)
    Article
    Restricted access - publisher's policy
    Direct ink writing (DIW) techniques open up new possibilities for the fabrication of patient-specific bone grafts. Self-setting calcium phosphate inks, which harden at low temperature, allow obtaining nanostructured scaffolds ...
  • Biomimetic versus sintered calcium phosphates: The in vitro behavior of osteoblasts and mesenchymal stem cells 

    Sadowska, Joanna Maria; Guillem Martí, Jordi; Montufar Jiménez, Edgar Benjamin; Español Pons, Montserrat; Ginebra Molins, Maria Pau (2017-12-01)
    Article
    Open Access
    © Copyright 2017, Mary Ann Liebert, Inc.The fabrication of calcium phosphates using biomimetic routes, namely, precipitation processes at body temperature, results in distinct features compared to conventional sintered ...
  • Brushite foams - the effect of Tween® 80 and Pluronic® F-127 on foam porosity and mechanical properties 

    Unosson, Johanna; Montufar Jiménez, Edgar Benjamin; Engqvist, Hakan; Ginebra Molins, Maria Pau; Persson, Cecilia (2015-01-23)
    Article
    Open Access
    Covenantee:  Uppsala universitet
    Resorbable calcium phosphate based bone void fillers should work as temporary templates for new bone formation. The incorporation of macropores with sizes of 100 -300 µm has been shown to increase the resorption rate of ...
  • Calcium phosphate cements as drug delivery materials 

    Ginebra Molins, Maria Pau; Canal Barnils, Cristina; Español Pons, Montserrat; Pastorino, David; Montufar Jiménez, Edgar Benjamin (2012-01-25)
    Article
    Restricted access - publisher's policy
    Calcium phosphate cements are used as synthetic bone grafts, with several advantages, such as their osteoconductivity and injectability. Moreover, their low-temperature setting reaction and intrinsic porosity allow for the ...
  • Comparison of a low molecular weight and a macromolecular surfactant as foaming agents for injectable self setting hydroxyapatite foams: Polysorbate 80 versus gelatine 

    Montufar Jiménez, Edgar Benjamin; Traykova, Tania; Planell Estany, Josep Anton; Ginebra Molins, Maria Pau (2011-10-10)
    Article
    Restricted access - publisher's policy
    Hydroxyapatite foams are potential synthetic bone grafting materials or scaffolds for bone tissue engineering. A novel method to obtain injectable hydroxyapatite foams consists in foaming the liquid phase of a calcium phosphate ...
  • Critical review: injectability of calcium phosphate pastes and cements 

    Ginebra Molins, Maria Pau; O'Neill, Rory; Montufar Jiménez, Edgar Benjamin; Wilson, D.I.; Lennon, A.; Dunne, Nicholas (2016-11-09)
    Article
    Open Access
    Covenantee:  Dublin City University
    Calcium phosphate cements (CPC) have seen clinical success in many dental and orthopaedic applications in recent years. The properties of CPC essential for clinical success are reviewed in this article, which includes ...
  • Extent and mechanism of phase separation during the extrusion of calcium phosphate pastes 

    O'Neill, Rory; McCarthy, Hellen O.; Cunningham, Eoin; Montufar Jiménez, Edgar Benjamin; Ginebra Molins, Maria Pau; Wilson, Ian; Lennon, Alex; Dunne, Nicholas (Springer, 2016-02)
    Article
    Open Access
    Covenantee:  Queen's University of Belfast
    The aim of this study was to increase understanding of the mechanism and dominant drivers influencing phase separation during ram extrusion of calcium phosphate (CaP) paste for orthopaedic applications. The liquid content ...
  • Focus ion beam/scanning electron microscopy characterization of osteoclastic resorption of calcium phosphate substrates 

    Díez Escudero, Anna; Español Pons, Montserrat; Montufar Jiménez, Edgar Benjamin; Pompo, Gemma di; Ciapetti, Gabriela; Baldini, Nicola; Ginebra Molins, Maria Pau (2017-02-01)
    Article
    Open Access
    Covenantee:  Istituto Ortopedico Rizzoli
    This article presents the application of dual focused ion beam/scanning electron microscopy (FIB-SEM) imaging for preclinical testing of calcium phosphates with osteoclast precursor cells and how this high-resolution imaging ...
  • In vivo efficiency of antimicrobial inorganic bone grafts in osteomyelitis treatments 

    Mestres Beà, Gemma; Fernández Yague, Marc Antoni; Pastorino Carraz, David; Montufar Jiménez, Edgar Benjamin; Canal Barnils, Cristina; Manzanares Céspedes, Maria Cristina; Ginebra Molins, Maria Pau (Elsevier, 2019-04-01)
    Article
    Restricted access - author's decision
  • In vivo performance of novel soybean/gelatin-based bioactive and injectable hydroxyapatite foams 

    Kovtun, Anna; goeckelmann, Melanie J.; Montufar Jiménez, Edgar Benjamin; Ginebra Molins, Maria Pau; Planell Estany, Josep Anton; Santin, Matteo; Ignatius, Anita (2015-01-15)
    Article
    Open Access
    Major limitations of calcium phosphate cements (CPCs) are their relatively slow degradation rate and the lack of macropores allowing the ingrowth of bone tissue. The development of self-setting cement foams has been proposed ...
  • New processing approaches in calcium phosphate cements and their applications in regenerative medicine 

    Ginebra Molins, Maria Pau; Español Pons, Montserrat; Montufar Jiménez, Edgar Benjamin; Pérez, R. A.; Mestres Beà, Gemma (2010-08)
    Article
    Restricted access - publisher's policy
    The key feature of calcium phosphate cements (CPCs) lies in the setting reaction triggered by mixing one or more solid calcium phosphate salts with an aqueous solution. Upon mixture, the reaction takes place through a ...
  • Novel soybean/gelatine-based bioactive and injectable hydroxyapatite foam: material properties and cell response 

    Baldini, Nicola; Perut, Francesca; Montufar Jiménez, Edgar Benjamin; Ciapetti, Gabriela; Santin, Matteo; Salvage, J; Traykova, Tania; Planell Estany, Josep Anton; Ginebra Molins, Maria Pau (2010-12-10)
    Article
    Restricted access - publisher's policy
    Covenantee:  Istituto Ortopedico Rizzoli
    Despite their known osteoconductivity, clinical use of calcium phosphate cements is limited both by their relatively slow rate of resorption and by rheological properties incompatible with injectability. Bone in-growth and ...
  • Osteoclast differentiation from human blood precursors on biomimetic calcium-phosphate substrates 

    Ciapetti, Gabriela; Pompo, Gemma di; Avnet, Sofia; Martini, Desirée; Díez Escudero, Anna; Montufar Jiménez, Edgar Benjamin; Ginebra Molins, Maria Pau; Baldini, Nicola (2017-03-01)
    Article
    Open Access
    Covenantee:  Istituto Ortopedico Rizzoli
    The design of synthetic bone grafts to foster bone formation is a challenge in regenerative medicine. Understanding the interaction of bone substitutes with osteoclasts is essential, since osteoclasts not only drive a ...
  • Osteogenesis by foamed and 3D-printed nanostructured calcium phosphate scaffolds: Effect of pore architecture 

    Barba, Albert; Maazouz, Yassine; Díez Escudero, Anna; Español Pons, Montserrat; Montufar Jiménez, Edgar Benjamin; Ginebra Molins, Maria Pau (Elsevier, 2018-10-01)
    Article
    Restricted access - publisher's policy
    There is an urgent need of synthetic bone grafts with enhanced osteogenic capacity. This can be achieved by combining biomaterials with exogenous growth factors, which however can have numerous undesired side effects, but ...
  • Osteoinduction by foamed and 3D-printed calcium phosphate scaffolds: effect of nanostructure and pore architecture 

    Barba Serrahima, Albert; Díez Escudero, Anna; Maazouz, Yassine; Rappe, K.; Español Pons, Montserrat; Montufar Jiménez, Edgar Benjamin; Bonany Mariñosa, Mar; Sadowska, Joanna Maria; Guillem Martí, Jordi; Ohman, Caroline; Persson, Cecilia; Manzanares, Maria Cristina; Franch Serracanta, Jordi; Ginebra Molins, Maria Pau (2017-12-06)
    Article
    Open Access
    Covenantee:  Universitat Autònoma de Barcelona. Departament de Medicina i Cirurgia Animal / Universitat de Barcelona. Departament de Patologia i Terapèutica Experimental
    Some biomaterials are osteoinductive, that is, they are able to trigger the osteogenic process by inducing the differentiation of mesenchymal stem cells to the osteogenic lineage. Although the underlying mechanism is still ...
  • Relevance of the setting reaction to the injectability of tricalcium phosphate pastes 

    Ginebra Molins, Maria Pau; Montufar Jiménez, Edgar Benjamin; Maazouz, Yassine (2013-04-09)
    Article
    Open Access
    The ai m of the present work was to analyze the influence of the setting reaction on the injectability of tricalcium phosphate (TCP) pastes. Even if the injection was performed early after mixing powder and liquid, ...
  • Robocasting of biomimetic hydroxyapatite scaffolds using self-setting inks 

    Maazouz, Yassine; Montufar Jiménez, Edgar Benjamin; Guillem Martí, Jordi; Fleps, I.; Ohman, C.; Persson, C.; Ginebra Molins, Maria Pau (Royal Society of Chemistry, 2014-01-01)
    Article
    Open Access
    Low temperature self-setting ceramic inks have been scarcely investigated for solid freeform fabrication processes. This work deals with the robocasting of alpha-tricalcium phosphate/gelatine reactive slurries as a bioinspired ...
  • Self-hardening and thermoresponsive alpha tricalcium phosphate/pluronic pastes 

    Maazouz, Yassine; Montufar Jiménez, Edgar Benjamin; Malbert, Julien; Español Pons, Montserrat; Ginebra Molins, Maria Pau (2017-02)
    Article
    Open Access
    Although calcium phosphate cements (CPCs) are used for bone regeneration in a wide range of clinical applications, various physicochemical phenomena are known to hinder their potential use in minimally invasive surgery or ...
  • Self-hardening calcium deficient hydroxyapatite-gelatine foams for bone regeneration 

    Montufar Jiménez, Edgar Benjamin; Traykova, Tania; Schacht, Etienne; Ambrosio, Luigi; Santin, Matteo; Planell Estany, Josep Anton; Ginebra Molins, Maria Pau (2009-10-30)
    Article
    Restricted access - publisher's policy
    In this work gelatine was used as multifunctional additive to obtain injectable self-setting hydroxyapatite/ gelatine composite foams for bone regeneration. The foaming and colloidal stabilization properties of gelatine ...