Exploració per autor "Langohr, Klaus"
Ara es mostren els items 1-20 de 35
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5-HTTLPR polymorphism, mood disorders and MDMA use in a 3-year follow-up study
de la Torre, Rafael; Martín-Santos, Rocío; Torrens, M.; Poudevida, Sandra; Langohr, Klaus; Cuyas, Elisabet; Pacifici, Roberta; Farré, Magí; Pichini, Simona (2010-01)
Article
Accés restringit per política de l'editorialA 3-year longitudinal prospective study was conducted to compare the incidence of substance use disorders (SUD) and non-substance use disorders (NSUD) among ecstasy users and two control groups: one of cannabis users and ... -
A lower olfactory capacity Is related to higher circulating concentrations of endocannabinoid 2-arachidonoylglycerol and higher body mass index in women
Pastor, Antoni; Fernández-Aranda, Fernando; Fitó, Montserrat; Jiménez-Murcia, Susana; Botella, Cristina; Fernández-Real, Jose M.; Frühbeck, Gema; Tinahones, Francisco; Fagundo, Ana; Rodriguez, Joan; Agüera, Zaida; Langohr, Klaus; Casanueva, Felipe F.; de la Torre, Rafael (2016)
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Accés obertThe endocannabinoid (eCB) system can promote food intake by increasing odor detection in mice. The eCB system is over-active in human obesity. Our aim is to measure circulating eCB concentrations and olfactory capacity in ... -
A new cognitive evaluation battery for Down syndrome and its relevance for clinical trials
de Sola Llopis, Susana; De la Torre Fornell, Rafael; Sánchez Benavides, Gonzalo; Benejam, Bessy; Cuenca, Aída; del Hoyo, Laura; Rodríguez, Joan; Catuara-Solarz, Silvina; Sánchez-Gutiérrez, Judit; Dueñas-Espín, Ivan; Hernández, Gimena; Peña-Casanovas, Jordi; Langohr, Klaus; Videla, Sebastià; Blehaut, Henri; Farré, Magí; Dierssen, Mara (2015-06-04)
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Accés obertThe recent prospect of pharmaceutical interventions for cognitive impairment of Down syndrome (DS) has boosted a number of clinical trials in this population. However, running the trials has raised some methodological ... -
Clinical Pharmacology of 3,4-Methylenedioxymethamphetamine (MDMA, "Ecstasy''): the influence of gender and genetics (CYP2D6, COMT, 5-HTT)
Pardo-Lozano, Ricardo; Farré, Magí; Yubero-Lahoz, Samanta; O’Mathúna, Brian; Torrens, M.; Mustata, Cristina; Pérez-Mañá, Clara; Langohr, Klaus; Cuyàs, Elisabet; Carbó, Marcel·lí; de la Torre, Rafael (2012-10-24)
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Accés obertThe synthetic psychostimulant MDMA (63,4-methylenedioxymethamphetamine, ecstasy) acts as an indirect serotonin, dopamine, and norepinephrine agonist and as a mechanism-based inhibitor of the cytochrome P-450 2D6 (CYP2D6). ... -
Combined treatment with environmental enrichment and (-)-epigallocatechin-3-gallate ameliorates learning deficits and hippocampal alterations in a mouse model of Down Syndrome
Catuara-Solarz, Silvina; Espinoa Carrasco, Jose; Erb, Ionas; Langohr, Klaus; González, Juan Ramon; Notredame, Cedric; Dierssen, Mara (2016-11-08)
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Accés obertIntellectual disability in Down syndrome (DS) is accompanied by altered neuro-architecture, deficient synaptic plasticity, and excitation-inhibition imbalance in critical brain regions for learning and memory. Recently, ... -
Deep sclerectomy with supraciliary hema implant (Esnoper (R) V-2000): results and complications
Loscos, Jordi; Valldeperas, X.; Langohr, Klaus; Parera, A.; Romera, Pau; Sabala, Antoni; de la Cámara, Javier (2015-10-01)
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Accés obertThe aim was to report the results of deep sclerectomy (DS) with supraciliary hema implant and the influence of the surgical complications on intraocular pressure (IOP). Forty-eight eyes of 41 patients with open angle ... -
Effect of physical fitness and endurance exercise on indirect biomarkers of growth hormone and insulin misuse: immunoassay-based measurement in urine samples
Zuccaro, Piergiorgio; Segura, Jordi; Pacifici, Roberta; Pichini, Simona; Ventura, Rosa; Palmi, Ilaria; Di Carlo, Simonetta; Bacosi, Antonella; Langohr, Klaus; Abellan, Rosario; Pascual, Jose Antonio (2010)
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Accés restringit per política de l'editorialIndirect biomarkers of recombinant human growth hormone (rhGH), insulin-like growth factor-I (IGF-I), insulin-like growth factor-II (IGF-II), insulin-like growth factor binding proteins (IGFBP-2 and IGFBP-3) and insulin ... -
Ethanol induces hydroxytyrosol formation in humans
Pérez-Mañá, Clara; Farré, Magí; Pujadas, Mitona; Mustata, Cristina; Menoyo, Ester; Pastor, Antoni; Langohr, Klaus; De la Torre Fornell, Rafael (2015)
Article
Accés obertPrevious studies in animals have shown an increase of hydroxytyrosol (OHTyr), a potent phenolic antioxidant and a minor metabolite of dopamine (also called 3,4-dihydroxyphenylethanol or DOPET), after ethanol intake. The ... -
Factors associated with discharge against medical advice from an alcohol and drug inpatient detoxifcation unit in Barcelona between 1993 and 2006
Gilchrist, Gail; Langohr, Klaus; Fonseca, Francina; Muga, Robert; Torrens, Marta (2012)
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Accés obertRecords from 1,228 consecutively admitted patients (74.5% male) to an inpatient detoxification unit in Barcelona between 1993 and 2006 were examined to determine factors associated with discharge against medical advice ... -
FHtest: an R package for the comparison of survival curves with censored data
Oller Piqué, Ramón; Langohr, Klaus (2017-11)
Article
Accés obertThe Fleming-Harrington class for right-censored data was first introduced by Harrington and Fleming (1982). This class is widely used in survival analysis studies and it is a subset of the so-called weighted logrank test ... -
Glucocorticoid receptors, brain-derived neurotrophic factor, serotonin and dopamine neurotransmission are associated with interferon-induced depression
Udina, Marc; Navinés, Ricard; Egmond, E.; Oriolo, G.; Langohr, Klaus; Giménez, Dolors; Valdés, M.; Gomez Gil, E.; Grande, I.; Gratacos, M.; Kapczinski, F.; Artigas, F.; Vieta, E.; Sola, R.; Martin Santos, R. (2016-12-30)
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Accés obertBackground: The role of inflammation in mood disorders has received increased attention. There is substantial evidence that cytokine therapies, such as interferon alpha (IFN-alpha), can induce depressive symptoms. Indeed, ... -
High risk and probability of progression to osteoporosis at 10 years in HIV-infected individuals: the role of PIs
Negredo Puigmal, Eugènia; Langohr, Klaus; Bonjoch Badia, Anna; Pérez Álvarez, Nuria; Estany Quera, Carla; Puig, Jordi; Echevarría, Patricia; Clotet Sala, Bonaventura; Gómez Melis, Guadalupe (2018-09-01)
Article
Accés restringit per política de l'editorial -
Importancia de la potencia y la hipótesis en el valor p
Cortés Martínez, Jordi; Casals, Martí; Langohr, Klaus; González Alastrué, José Antonio (Elsevier, 2015-12-09)
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Accés obertLos lectores de Medicina Clínica conocen bien la importancia de definir bien el denominador de una proporción para estimar una probabilidad: “No es lo mismo la probabilidad de que un católico sea Papa que la de que un Papa ... -
Incidence of infectious diseases and survival among the Roma population: a longitudinal cohort study
Casals, Martí; Pila, Pilar; Langohr, Klaus; Millet, Juan-Pablo; Caylà, J (Oxford University Press, 2011-01-07)
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Accés obertBackground: Roma ethnicity is greatly affected by tuberculosis (TB), AIDS, injecting drugs use (IDU) and imprisonment. Methods: We assessed the incidence of several health problems by means of a retrospective cohort study ... -
Incidence of injuries in competition of Leonese wrestling and associated factors (2005–2015) Incidencia de lesiones en la competición de Lucha Leonesa y Factores Asociados (2005-2015)
Martín Sánchez, Vicente; Blasco, María J.; Casals Toquero, Martí; Langohr, Klaus (2018-09)
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Accés restringit per política de l'editorialIntroducción: La lucha tradicional es considerada un patrimonio cultural de la humanidad que debe protegerse. El estudio de las lesiones y sus factores asociados puede favorecer la protección de este patrimonio. El presente ... -
Lesiones en la lucha tradicional: el caso de la lucha leonesa (2005-2015)
Blasco Carmona, M. J.; Casals Toquero, Martí; Fernández Villa, Tania; Langohr, Klaus (2018-12-01)
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Accés obertEl objetivo de este estudio fue describir la localización anatómica, el tipo y la gravedad de las lesiones ocurridas en las competiciones oficiales de las ligas de verano masculinas (2005-2015) de Lucha Leonesa. Al objeto ... -
Multiple imputation approach for interval-censored time to HIV RNA viral rebound within a mixed effects Cox model
Alarcón Soto, Yovaninna; Langohr, Klaus; Fehér, C.; García Alcaide, Felipe; Gómez Melis, Guadalupe (2018-01-01)
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Accés obertWe present a method to fit a mixed effects Cox model with interval-censored data. Our proposal is based on a multiple imputation approach that uses the truncated Weibull distribution to replace the interval-censored data ... -
Non-linear formation of EtG and FAEEs after controlled administration of low to moderate doses of ethanol
Pérez-Mañá, Clara; Farré, Magí; Pastor, Antoni; Fonseca, Francina; Torrens, Marta; Menoyo, Ester; Pujadas, Mitona; Frias, Silvia; Langohr, Klaus; De la Torre Fornell, Rafael (2017-09-01)
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Accés obertAims Ethyl glucuronide (EtG) and fatty acid ethyl esters (FAEEs) are non-oxidative metabolites of alcohol that can be detected in conventional and non-conventional biological matrices for longer periods than alcohol. The ... -
Parameter estimation of Poisson generalized linear mixed models based on three different statistical principles: a simulation study
Casals, Martí; Langohr, Klaus; Carrasco, Josep Lluís; Rönnegård, Lars (Institut d'Estadística de Catalunya, 2015-12)
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Accés obertGeneralized linear mixed models are flexible tools for modeling non-normal data and are useful for accommodating overdispersion in Poisson regression models with random effects. Their main difficulty resides in the parameter ... -
Parameter estimation of Poisson generalized linear mixed models based on three different statistical principles: a simulation study
Casals, Martí; Langohr, Klaus; Carrasco, Josep Lluís; Rönnegård, Lars (Institut d'Estadística de Catalunya, 2015-12)
Article
Accés obertGeneralized linear mixed models are flexible tools for modeling non-normal data and are usefulfor accommodating overdispersion in Poisson regression models with random effects. Theirmain difficulty resides in the parameter ...