Browsing by Author "Tinajero, Ernesto"
Now showing items 1-19 of 19
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Block and graft copolymers made of 16-membered macrolactones and l-Alanine: a comparative study
(2019-08-01)
Article
Open AccessBlock and graft poly(macrolactone)-poly(a-amino acid) copolymers made of l-alanine and pentadecalactone or globalide respectively, are prepared. A sequential ring-opening polymerization (ROP) copolymerization route consisting ... -
Copolymacrolactones grafted with L-glutamic acid: Synthesis, structure, and nanocarrier properties
(Multidisciplinary Digital Publishing Institute (MDPI), 2020-04-24)
Article
Open AccessThe enzymatic ring-opening copolymerization (eROP) of globalide (Gl) and pentadecalactone (PDL) was performed in solution from mixtures of the two macrolactones at ratios covering the whole range of comonomeric compositions. ... -
Digital light processing of thermoresponsive hydrogels from polyproline-based star polypeptides
(2024-09-13)
Article
Open AccessThe first report of star poly(L-proline) crosslinkers is disclosed for digital light processing 3D printing of thermoresponsive hydrogels. Through chain end functionalization of star poly(L-proline)s with methacryloyl ... -
Enzymatic crosslinked hydrogels of gelatin and poly (vinyl alcohol) loaded with probiotic bacteria as oral delivery system
(Multidisciplinary Digital Publishing Institute (MDPI), 2022-12-09)
Article
Open AccessProbiotic bacteria are widely used to prepare pharmaceutical products and functional foods because they promote and sustain health. Nonetheless, probiotic viability is prone to decrease under gastrointestinal conditions. ... -
Green metallic nanoparticles for cancer therapy: evaluation models and cancer applications
(2021-10-18)
Article
Open AccessMetal-based nanoparticles are widely used to deliver bioactive molecules and drugs to improve cancer therapy. Several research works have highlighted the synthesis of gold and silver nanoparticles by green chemistry, using ... -
Hybrid block and graft copolymers made from macrolactones and α-amino acids for applications as drug delivery nanosystems
(Universitat Politècnica de Catalunya, 2019-07-17)
Doctoral thesis
Open AccessNaturally produced peptides or proteins can be regarded as highly refined polymers. When synthetic polymers are married to proteins or peptides, the resulting bioconjugates can synergistically combine the properties of the ... -
In situ formation of nanoparticles from graft copolypeptides under dispersion polymerization conditions
(2025-04-28)
Article
Open AccessA simple method is presented for preparing polypeptide nanoparticles using hydrophilic biosynthetic e-poly(lysine) (ePL) as a reactive surfactant under dispersion polymerization conditions. In situ graft polymerization of ... -
Metal-free catalyzed ring-opening polymerization and block copolymerization of ¿-pentadecalactone using amino-ended initiators
(Elsevier, 2018-11-01)
Article
Open AccessMetal-free catalysis was successfully applied to polymerize ¿-pentadecalactone (PDL) by ring-opening polymerization (ROP) using several amino-ended initiators, namely hexylamine, allylamine and O,O'-bis(3-aminopropyl)diethylene ... -
pH-responsive diblock copolymers made of omega-pentadecalactone and ionically charged alpha-amino acids
(Elsevier, 2019-11-01)
Article
Open AccessTwo sets of ionically charged polypentadecalactone-polypeptide diblock copolymers (PPDLx-b-PAAy, with x= 15 or 20 and y ranging from 30 to 200), one containing alpha-L-glutamic acid (LGA) and the other containing ... -
Poly(amino acid)-grafted polymacrolactones. Synthesis, self-assembling and ionic coupling properties
(2019-01-01)
Article
Open AccessPolyglobalide (PGl) with number average polymerization degree of ~20 was prepared by enzymatic ROP and then polyfunctionalized at 60% with aminothioethylene groups. The PGl20-(NH2)12 copolymer was used as macroinitiator ... -
Poly(ether-ester-peptide) triblock copolymers: Synthesis and self-assembly behavior
(Universidad de Burgos. Servicio de publicaciones e imagen institucional, 2019)
Conference lecture
Restricted access - publisher's policyTriblock/grafted poly(ether-ester-peptide) copolymers made or PEG, poly(globablide) and poly(L-phenylalanine) were synthesized by sequential ROP starting from diaminated PEG as first initiator. The aromatic functionality ... -
Poly(L-proline)-stabilized polypeptide nanostructures via Ring-Opening Polymerization-Induced Self-Assembly (ROPISA)
(American Chemical Society (ACS), 2024-07-29)
Article
Open AccessPoly(proline) II helical motifs located at the protein–water interface stabilize the three-dimensional structures of natural proteins. Reported here is the first example of synthetic biomimetic poly(proline)-stabilized ... -
Polypeptide-based materials prepared by ring-opening polymerisation of anionic-based alpha-amino acid N-carboxyanhydrides: A platform for delivery of bioactive-compounds
(2021-09)
Article
Open AccessPolymerisation of a-amino acid N-carboxyanhydrides (NCAs) is one of the most common techniques to prepare synthetic polypeptides. Of special interest are the NCAs derived from a-amino acids, L-aspartic acid and L-glutamic ... -
QUÍMICA I (Examen final 1r quadrimestre)
(Universitat Politècnica de Catalunya, 2025-01-25)
Exam
Restricted access to the UPC academic community -
QUÍMICA I (Examen parcial 1r quadrimestre)
(Universitat Politècnica de Catalunya, 2024-10-31)
Exam
Restricted access to the UPC academic community -
QUÍMICA I (Examen parcial 2n quadrimestre)
(Universitat Politècnica de Catalunya, 2025-04-08)
Exam
Restricted access to the UPC academic community -
Ring opening polymerization of macrolactones using amines as initiators
(2016)
Conference lecture
Open AccessThe ring opening polymerization (ROP) of these macrolactones mediated by alcohols as initiators and organic and metal-based catalysts has been reported before with satisfactory results [4,5]. In the present work, the ... -
Synthesis and properties of diblock copolymers of omega-pentadecalactone and alpha-amino acids
(Elsevier, 2019-07-01)
Article
Open AccessDiblock copolymers (PPDLx-b-pPAAy) were prepared from ¿-pentadecalactone and l-glutamic acid or l-lysine amino acids by ring opening polymerization initiated by amino groups. Telechelic amino-ended poly(¿-pentadecalactone) ... -
Validation of smart nanoparticles as controlled drug delivery systems: loading and pH-dependent release of pilocarpine
(American Chemical Society (ACS), 2017-09-25)
Article
Open AccessMicelles are good devices for use as controlled drug delivery systems because they exhibit the ability to protect the encapsulated substance from the routes of degradation until they reach the site of action. The present ...
