Exploració per autor "Tinajero, Ernesto"
Ara es mostren els items 1-13 de 13
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Block and graft copolymers made of 16-membered macrolactones and l-Alanine: a comparative study
Tinajero, Ernesto; Martínez de Ilarduya Sáez de Asteasu, Domingo Antxon; Muñoz Guerra, Sebastián (2019-08-01)
Article
Accés obertBlock and graft poly(macrolactone)-poly(a-amino acid) copolymers made of l-alanine and pentadecalactone or globalide respectively, are prepared. A sequential ring-opening polymerization (ROP) copolymerization route consisting ... -
Copolymacrolactones grafted with L-glutamic acid: Synthesis, structure, and nanocarrier properties
Tinajero, Ernesto; Martínez de Ilarduya Sáez de Asteasu, Domingo Antxon; Muñoz Guerra, Sebastián (Multidisciplinary Digital Publishing Institute (MDPI), 2020-04-24)
Article
Accés obertThe enzymatic ring-opening copolymerization (eROP) of globalide (Gl) and pentadecalactone (PDL) was performed in solution from mixtures of the two macrolactones at ratios covering the whole range of comonomeric compositions. ... -
Enzymatic crosslinked hydrogels of gelatin and poly (vinyl alcohol) loaded with probiotic bacteria as oral delivery system
Corona Escalera, Aldo F.; Tinajero, Ernesto; García Reyes, Rudy A.; Luna Bárcenas, Gabriel; Seyfoddin, Ali; Padilla de la Rosa, José Daniel; González Ávila, Marisela; García Carvajal, Zaira Yunuen (Multidisciplinary Digital Publishing Institute (MDPI), 2022-12-09)
Article
Accés obertProbiotic bacteria are widely used to prepare pharmaceutical products and functional foods because they promote and sustain health. Nonetheless, probiotic viability is prone to decrease under gastrointestinal conditions. ... -
Green metallic nanoparticles for cancer therapy: evaluation models and cancer applications
Tinajero, Ernesto; Salado Leza, Daniela; González Castillo, María del Carmen; Martínez Velázquez, Moisés; López, Zaira; Bravo Madrigal, Jorge; Knauth, Peter; Flores Hernández, Flor Y.; Herrera Rodríguez, Sara Elisa; Navarro González, Rosa Estela; Cabrera Wrooman, Alejandro; Krotzsch, Edgar; García Carvajal, Zaira Yunuen; Hernández Gutiérrez, Rodolfo (2021-10-18)
Article
Accés obertMetal-based nanoparticles are widely used to deliver bioactive molecules and drugs to improve cancer therapy. Several research works have highlighted the synthesis of gold and silver nanoparticles by green chemistry, using ... -
Hybrid block and graft copolymers made from macrolactones and α-amino acids for applications as drug delivery nanosystems
Tinajero, Ernesto (Universitat Politècnica de Catalunya, 2019-07-17)
Tesi
Accés obertNaturally produced peptides or proteins can be regarded as highly refined polymers. When synthetic polymers are married to proteins or peptides, the resulting bioconjugates can synergistically combine the properties of the ... -
Metal-free catalyzed ring-opening polymerization and block copolymerization of ¿-pentadecalactone using amino-ended initiators
Tinajero, Ernesto; Martínez de Ilarduya Sáez de Asteasu, Domingo Antxon; Muñoz Guerra, Sebastián; de Paz, Maria Viola; Galbis Fuster, Elsa (Elsevier, 2018-11-01)
Article
Accés obertMetal-free catalysis was successfully applied to polymerize ¿-pentadecalactone (PDL) by ring-opening polymerization (ROP) using several amino-ended initiators, namely hexylamine, allylamine and O,O'-bis(3-aminopropyl)diethylene ... -
pH-responsive diblock copolymers made of omega-pentadecalactone and ionically charged alpha-amino acids
Tinajero, Ernesto; Martínez de Ilarduya Sáez de Asteasu, Domingo Antxon; Muñoz Guerra, Sebastián (Elsevier, 2019-11-01)
Article
Accés obertTwo sets of ionically charged polypentadecalactone-polypeptide diblock copolymers (PPDLx-b-PAAy, with x= 15 or 20 and y ranging from 30 to 200), one containing alpha-L-glutamic acid (LGA) and the other containing ... -
Poly(amino acid)-grafted polymacrolactones. Synthesis, self-assembling and ionic coupling properties
Tinajero, Ernesto; Martínez de Ilarduya Sáez de Asteasu, Domingo Antxon; Cavanagh, Breton; Heise, Andreas; Muñoz Guerra, Sebastián (2019-01-01)
Article
Accés obertPolyglobalide (PGl) with number average polymerization degree of ~20 was prepared by enzymatic ROP and then polyfunctionalized at 60% with aminothioethylene groups. The PGl20-(NH2)12 copolymer was used as macroinitiator ... -
Poly(ether-ester-peptide) triblock copolymers: Synthesis and self-assembly behavior
Tinajero, Ernesto; Martínez de Ilarduya Sáez de Asteasu, Domingo Antxon; Muñoz Guerra, Sebastián (Universidad de Burgos. Servicio de publicaciones e imagen institucional, 2019)
Comunicació de congrés
Accés restringit per política de l'editorialTriblock/grafted poly(ether-ester-peptide) copolymers made or PEG, poly(globablide) and poly(L-phenylalanine) were synthesized by sequential ROP starting from diaminated PEG as first initiator. The aromatic functionality ... -
Polypeptide-based materials prepared by ring-opening polymerisation of anionic-based alpha-amino acid N-carboxyanhydrides: A platform for delivery of bioactive-compounds
Tinajero, Ernesto; Kimmins, Scott D; García-Carvajal, Zaira-Yunuen; Martínez de Ilarduya Sáez de Asteasu, Domingo Antxon (2021-09)
Article
Accés obertPolymerisation of a-amino acid N-carboxyanhydrides (NCAs) is one of the most common techniques to prepare synthetic polypeptides. Of special interest are the NCAs derived from a-amino acids, L-aspartic acid and L-glutamic ... -
Ring opening polymerization of macrolactones using amines as initiators
Tinajero, Ernesto; Lavilla, Cristina; Martínez de Ilarduya Sáez de Asteasu, Domingo Antxon; Muñoz Guerra, Sebastián (2016)
Comunicació de congrés
Accés obertThe ring opening polymerization (ROP) of these macrolactones mediated by alcohols as initiators and organic and metal-based catalysts has been reported before with satisfactory results [4,5]. In the present work, the ... -
Synthesis and properties of diblock copolymers of omega-pentadecalactone and alpha-amino acids
Tinajero, Ernesto; Martínez de Ilarduya Sáez de Asteasu, Domingo Antxon; Muñoz Guerra, Sebastián (Elsevier, 2019-07-01)
Article
Accés obertDiblock copolymers (PPDLx-b-pPAAy) were prepared from ¿-pentadecalactone and l-glutamic acid or l-lysine amino acids by ring opening polymerization initiated by amino groups. Telechelic amino-ended poly(¿-pentadecalactone) ... -
Validation of smart nanoparticles as controlled drug delivery systems: loading and pH-dependent release of pilocarpine
Galbis Fuster, Elsa; Iglesias González, Nieves; Lucas Rodríguez, Ricardo; Tinajero, Ernesto; Muñoz Guerra, Sebastián (American Chemical Society (ACS), 2017-09-25)
Article
Accés obertMicelles are good devices for use as controlled drug delivery systems because they exhibit the ability to protect the encapsulated substance from the routes of degradation until they reach the site of action. The present ...