Now showing items 1-8 of 8

    • Cold plasma-activated Ringer’s solution exacerbates stemness phenotype of cancer cells in an osteosarcoma tissue-engineered model [Dataset] 

      Tornin Cavielles, Juan; Villasante, Aranzazu; Sole Marti, Xavi; Ginebra Molins, Maria Pau; Canal Barnils, Cristina (Universitat Politècnica de Catalunya, 2020)
      Dataset
      Restricted access - author's decision
      The use of Cold Atmospheric Plasma (CAP) in oncology is being recently studied as a novel potential anti-cancer therapy. However, the beneficial effects of CAP for treating osteosarcoma have mostly been demonstrated in ...
    • Evaluation of the effects of cold atmospheric plasma and plasma-treated liquids in cancer cell cultures [Dataset] 

      Tornin Cavielles, Juan; Labay, Cédric Pierre; Tampieri, Francesco; Ginebra Molins, Maria Pau; Canal Barnils, Cristina (Universitat Politècnica de Catalunya, 2020)
      Dataset
      Open Access
      The present dataset corresponds to the anticipated results that can be obtained following the protocol described in the article. In particular, dataset corresponding to Figure 8 presents the absorbance values from the WST-1 ...
    • FUS-CHOP promotes invasion in myxoid liposarcoma through a SRC/FAK/RHO/ROCK-dependent pathway 

      Tornin Cavielles, Juan; Hermida Prado, Francisco; Singh Singh, Ranjit; González, M. Victoria (2017-01-28)
      Article
      Open Access
      Deregulated SRC/FAK signaling leads to enhanced migration and invasion in many types of tumors. In myxoid and round cell liposarcoma (MRCLS), an adipocytic tumor characterized by the expression of the fusion oncogene ...
    • Influence of the composition of plasma-activated medium on osteosarcoma 

      Canal Barnils, Cristina; Tornin Cavielles, Juan; Mateu, Miguel; Hamouda, Inés; Labay, Cédric Pierre; Guillem Martí, Jordi; Ginebra Molins, Maria Pau (2018)
      Conference report
      Open Access
    • Mithramycin delivery systems to develop effective therapies in sarcomas 

      Estupiñan, Oscar; Rey Vázquez, Verónica; Tornin Cavielles, Juan; Moris, Francisco; González Meana, M. Victoria (Springer Nature, 2021-12)
      Article
      Open Access
      Covenantee:   Instituto de Investigación Sanitaria del Principado de Asturias
      Sarcomas comprise a group of aggressive malignancies with very little treatment options beyond standard chemotherapy. Reposition of approved drugs represents an attractive approach to identify effective therapeutic compounds. ...
    • Osteosarcoma tissue-engineered model challenges oxidative stress therapy revealing promoted cancer stem cell properties 

      Tornin Cavielles, Juan; Villasante Bermejo, Aránzazu; Solé Martí, Xavier; Ginebra Molins, Maria Pau; Canal Barnils, Cristina (2021-02)
      Article
      Open Access
      Covenantee:   Instituto de Investigación Sanitaria del Principado de Asturias
      The use of oxidative stress generated by Cold Atmospheric Plasma (CAP) in oncology is being recently studied as a novel potential anti-cancer therapy. However, the beneficial effects of CAP for treating osteosarcoma have ...
    • Pyruvate plays a main role in the antitumoral selectivity of cold atmospheric plasma in osteosarcoma 

      Tornin Cavielles, Juan; Mateu Sanz, Miguel; Rodríguez, Aida; Labay, Cédric Pierre; Rodríguez, Rene; Canal Barnils, Cristina (Nature, 2019-07-23)
      Article
      Open Access
      Covenantee:   Hospital Universitario Central de Asturias / Instituto Universitario de Oncología del Principado de Asturias / Centro de Investigación Biomédica en Red. Bioingeniería, Biomateriales y Nanomedicina
      Osteosarcoma (os) is the most common primary bone tumor but current therapies still have poor prognosis. Cold Atmospheric Plasma (CAP) and Plasma activated media (PAM) have shown potential to eliminate cancer cells in other ...
    • The multikinase inhibitor EC‐70124 synergistically increased the antitumor activity of doxorubicin in sarcomas 

      Estupiñan, Oscar; Santos, Laura; Rodriguez, Aida; Fernandez-Nevado, Lucia; Costales, Paula; Perez‐Escuredo, Jhudit; Hermosilla, Maria Ana; Oro, Patricia; Rey, Veronica; Tornin Cavielles, Juan; Allonca, Eva; Fernandez Garcia, Maria Teresa; Alvarez Fernandez, Carlos; Braña, Alejandro; Astudillo, Aurora; T. Menendez, Sofia; Moris, Francisco; Rodriguez, Rene (Wiley (John Wiley & Sons), 2018-12-21)
      Article
      Open Access
      Cytotoxic drugs like doxorubicin remain as the most utilized agents in sarcoma treatment. However, advanced sarcomas are often resistant, thus stressing the need for new therapies aimed to overcome this resistance. Multikinase ...