Now showing items 1-9 of 9

    • A 3D-1D cardiac-vascular computational feedbacked model 

      Santiago, Alfonso; Vázquez, Mariano; Houzeaux, Guillaume; Aguado-Sierra, Jazmin; López, Mariña; Rivero, Matías I.; Blanco Sánchez, Pablo; Watanabe, Sansuke (Barcelona Supercomputing Center, 2015-05-05)
      Conference report
      Open Access
      A first version of a cardiovascular coupled model is presented. The modelling tools are Alya, the BSC tool for biomechanical simulations; and ADAN55, the LNCC model of the arterial blood flow. The former solves the ...
    • Containers in HPC: a scalability and portability study in production biological simulations 

      Rudyy, Oleksandr; Garcia Gasulla, Marta; Mantovani, Filippo; Santiago, Alfonso; Sirvent Pardell, Raül; Vázquez, Mariano (Barcelona Supercomputing Center, 2019-05-07)
      Conference report
      Open Access
    • Design and execution of a verification, validation, and uncertainty quantification plan for a numerical model of left ventricular flow after LVAD implantation 

      Santiago, Alfonso; Butakoff, Constantine; Eguzkitza, Beatriz; Gray, Richard A.; May-Newman, Karen; Pathmanathan, Pras; Vu, Vi; Vázquez, Mariano (Public Library of Science, 2022-06)
      Article
      Open Access
      BACKGROUND: Left ventricular assist devices (LVADs) are implantable pumps that act as a life support therapy for patients with severe heart failure. Despite improving the survival rate, LVAD therapy can carry major ...
    • Fluid-electro-mechanical model of the human heart for supercomputers 

      Santiago, Alfonso (Universitat Politècnica de Catalunya, 2018-03-22)
      Doctoral thesis
      Open Access
      The heart is a complex system. From the transmembrane cell activity to the spatial organization in helicoidal fibers, it includes several spatial and temporal scales. The heart muscle is surrounded by two main tissues that ...
    • Fluid–structure interaction of human nasal valves under sniff conditions and transport of inhaled aerosols: A numerical study 

      Calmet, Hadrien; Santiago, Alfonso; Cajas, Juan Carlos; Langdon, Cristobal; Eguzkitza, Beatriz; Houzeaux, Guillaume (Elsevier, 2022)
      Article
      Restricted access - publisher's policy
      The nasal valve is the narrowest part of the nasal airway which is responsible for the largest part of the nasal resistance. Even little changes in the aperture can affect the flow downstream through the nose significantly. ...
    • Fully-Coupled Electromechanical Simulations of the LV Dog Anatomy Using HPC: Model Testing and Verification 

      Aguado-Sierra, Jazmin; Santiago, Alfonso; Rivero, Matías I.; Lopez-Yunta, Mariña; Soto-Iglesias, David; Dux-Santoy, Lydia; Camara, Oscar; Vázquez, Mariano (Springer, 2015-01-01)
      Part of book or chapter of book
      Open Access
      Verification of electro-mechanic models of the heart require a good amount of reliable, high resolution, thorough in-vivo measurements. The detail of the mathematical models used to create simulations of the heart beat ...
    • HPC compact quasi-Newton algorithm for interface problems 

      Santiago, Alfonso; Zavala Aké, Miguel; Borrell Pol, Ricard; Houzeaux, Guillaume; Vázquez, Mariano (Elsevier, 2020)
      Article
      Open Access
      In this work we present a robust interface coupling algorithm called Compact Interface quasi-Newton (CIQN). It is designed for computationally intensive applications using an MPI multi-code partitioned scheme. The algorithm ...
    • Human biventricular electromechanical simulations on the progression of electrocardiographic and mechanical abnormalities in post-myocardial infarction 

      Wang, Zhinuo J; Santiago, Alfonso; Zhou, Xin; Wang, Lei; Margara, Francesca; Levrero-Florencio, Francesc; Das, Arka; Kelly, Chris; Dall'Armellina, Erica; Vázquez, Mariano; Rodriguez, Blanca (Oxford University Press, 2021-03)
      Article
      Open Access
      Aims Develop, calibrate and evaluate with clinical data a human electromechanical modelling and simulation framework for multiscale, mechanistic investigations in healthy and post-myocardial infarction (MI) conditions, ...
    • Validation and Sensitivity analysis for a nasal spray deposition computational model 

      Calmet, Hadrien; Oks, David; Santiago, Alfonso; Houzeaux, Guillaume; Le Corfec, Antoine; Deruyver, Laura; Rigaut, Clement; Lambert, Pierre; Haut, Benoit; Goole, Jonathan (Elsevier, 2022)
      Article
      Restricted access - publisher's policy
      Validating numerical models against experimental models of nasal spray deposition is challenging since many aspects must be considered. That being said, it is a critical step in the product development process of nasal ...