Browsing by Contributor "Sáez Viñas, Pablo"
Now showing items 1-15 of 15
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A computational model of single and collective cell migration
(Universitat Politècnica de Catalunya, 2022-07-15)
Master thesis
Open AccessCell migration is a fundamental mechanism in biology, including cancer or embryogenesis. Actin turnover plays a fundamental role in cell motility and it acts as an engine for the affective motion of motile cells by means ... -
A multi-scale theoretical model for soft materials
(Universitat Politècnica de Catalunya, 2018-09-27)
Bachelor thesis
Open AccessMany manufactured materials, such as rubbers, are made of several constituents with very different mechanical stiffness. Interestingly, the overall mechanical response of the material exhibits a very particular response ... -
Computational analysis of the remodeling in biological tissue
(Universitat Politècnica de Catalunya, 2022-10-14)
Master thesis
Open AccessAquest treball documenta una implementació d'un model de reorientació de fibres, o remodelació, a partir d'un material hiperelàstic anisòtrop. Es consideren dos models per a la deformació mecànica de les fibres: exponencial ... -
Computational model for the chemo-mechanical mechanism in wound healing
(Universitat Politècnica de Catalunya, 2017-06-16)
Master thesis
Open AccessWounds in multicellular tissue occur regularly through the lifetime of living organisms, and the closure of these gaps is fundamental for their healthy development. From the physiological point of view, the success in ... -
Computational modeling of brain development
(Universitat Politècnica de Catalunya, 2017-06-13)
Master thesis
Restricted access - author's decision
Covenantee: Centre Internacional de Mètodes Numèrics a l'EnginyeriaThe brain is one of the most exciting and unknown entities in nature. During development the brain folds towards a highly convoluted form. The topological features of the brain are also related to the deformation of the ... -
Computational modeling of single cell migration
(Universitat Politècnica de Catalunya, 2021-09)
Bachelor thesis
Open AccessCell migration is central to any biological process such as embryonic development, wound healing or cancer. Here we study the mechanisms the cell uses when moving as well as the main proteins involved like actin and myosin. ... -
Computational modelling of the actin flow
(Universitat Politècnica de Catalunya, 2018-06)
Master thesis
Open AccessActin turnover plays a fundamental role in cell motility, cancer or embryogenesis. The actin flow acts as an engine for the affective motion of motile cells by means of protrusive and retractile mechanisms conditioned also ... -
Computational models of mammalian brains in transient dynamics
(Universitat Politècnica de Catalunya, 2018-05-11)
Master thesis
Open AccessTo date, the brain remains the most intriguing and unexplored organ in humans. Understanding its mechanical behavior is crucial for the study of brain diseases involving brain deformation in traumatic brain injury. Despite ... -
Computational study of brain tissue response to mechanical loading
(Universitat Politècnica de Catalunya, 2023-10-10)
Master thesis
Open AccessAs the era of frequent human space travel nears, it becomes imperative to understand the brain’s reaction to microgravity conditions. This research delves into the intricate mechanics of brain tissue, focusing specifically ... -
Estudio computacional de las propiedades visco-hiperelásticas del tejido cerebral
(Universitat Politècnica de Catalunya, 2017-09-22)
Bachelor thesis
Restricted access - author's decisionLas propiedades mecánicas del tejido cerebral son motivo de estudio desde hace más de medio siglo. La mecánica del cerebro tiene un papel importante en las condiciones patológicas como las lesiones cerebrales, la ... -
Mathematical modelling of tumour growth in vitro
(Universitat Politècnica de Catalunya, 2017-07)
Master thesis
Restricted access - author's decisionIt is now widely accepted that cells are mechanically integrated structures which dynamically respond to mechanical cues. Tumours are no exception to that rule but still little is known on how this mechano-transduction is ... -
Multiscale clutch models for cell mechanics
(Universitat Politècnica de Catalunya, 2022-07-22)
Doctoral thesis
Open AccessIntegrin-based cell adhesion is a key mechanism in fundamental biological processes such as cell migration and wound healing, and in diseases like osteoporosis and cancer. For example, during migration, cells form adhesion ... -
Numerical model of cardiac electrochemistry
(Universitat Politècnica de Catalunya, 2021-05)
Bachelor thesis
Open AccessGiven the relevance of cardiac maladies in today's society, investigation driven towards the understanding of how our hearts work has been gaining importance. In this bachelor degree thesis we approach the matter by giving ... -
Numerical model of cardiac electromechanics
(Universitat Politècnica de Catalunya, 2019-10)
Master thesis
Open AccessIn this project, we develop a Finite Element Method (FEM) formulation that solves the cardiac electrophysiological problem of a three dimensional piece of tissue. This problem is modeled by an electromechanical model that ... -
Numerical modelling of the electrophysiology of the neuron
(Universitat Politècnica de Catalunya, 2017-07)
Master thesis
Restricted access - author's decisionA majority of studies on the brain are focused at either the molecular level or organ level. Rarely do we see models that attempt to relate neuronal behaviors to symptoms of traumatic brain injury. Well-documented studies ...
