Now showing items 1-20 of 25

    • Computational study of the role of SK channels in cardiac electrophysiology and implications for atrial fibrillation 

      Iniesta Jovaní, Sara (Universitat Politècnica de Catalunya, 2023-07-07)
      Bachelor thesis
      Open Access
      Covenantee:   BioCom SC
      This project investigates the role of SK channels in cardiac electrophysiology, particularly in relation to atrial fibrillation. The study explores the impact of SK channel modulation on action potential duration and the ...
    • Continuation methods: application to a biophysical problem 

      Caro Mañas, Ivan (Universitat Politècnica de Catalunya, 2019-09)
      Bachelor thesis
      Open Access
      The goal of this project is to study continuation methods and to learn how to implement them numerically. We will review the main points of the procedure and we will try to replicate these results numerically. Starting ...
    • Control of calcium homeostasis and load regulation in a ventricular Z- Plane model 

      Martin de Pablo, Luis (Universitat Politècnica de Catalunya, 2017-07)
      Bachelor thesis
      Open Access
      Calcium is considered one of the most important ions involved in the intricate workings of the heart. The control of intracellular calcium is crucial to the process called excitation-contraction coupling, enabling the ...
    • Controllability of a magnetic cell stretching device 

      Domingo Oriol, Antonio (Universitat Politècnica de Catalunya, 2018-06-24)
      Bachelor thesis
      Open Access
      The control of coordinated gene expression is one of the most important processes due to its importance in understanding diseases caused by genomic problems. For it, it is important to study the role of genomic DNA ...
    • Development of a cardiac model for the study of sudden cardiac death in infants 

      Alonso García-Cabezón, Mateo (Universitat Politècnica de Catalunya, 2021-09-15)
      Master thesis
      Open Access
      The Sudden Unexpected Death of an Infant (SUDI) is the unforeseen death of a newborn less than 12 months old. A mutation was discovered in a number of cases of SUDI that affects the protein troponin (Tn) present in ...
    • Effect of reactive oxygen species in the development of cardiac arrhythmias 

      Bosch Padrós, Miquel (Universitat Politècnica de Catalunya, 2019-06)
      Bachelor thesis
      Open Access
      Among all ions present in a cardiac cell, calcium is categorically the most important. It governs the contraction and relaxation of the heart chambers that enables pumping of blood throughout the body. Calcium mishandling ...
    • Estudio de técnicas electromagnéticas de prospección del subsuelo 

      Feria Rodríguez, Daniel (Universitat Politècnica de Catalunya, 2015-06-30)
      Master thesis (pre-Bologna period)
      Open Access
      Este estudio se basa principalmente en la Geofísica Aplicada, a la que muchos se refieren como Prospección Geofísica. Dicha ciencia es la aplicación de la Física al estudio de la parte más superficial de la corteza terrestre, ...
    • GPU-accelerated simulations of the chemotactic response of amoeba Dictyostelium discoideum 

      Casas Vidal, David (Universitat Politècnica de Catalunya, 2016-05-24)
      Bachelor thesis
      Open Access
      Firstly, the design and implementation of a generic framework that easies the creation of gpu-accelerated physical simulations. Secondly, it tests a model for the chemotactic response and locomotion of the amoeba Dictyostelium ...
    • Implications of inertial focusing in macroscale coronary flow 

      Santigosa Pinilla, Marc (Universitat Politècnica de Catalunya, 2017-06)
      Bachelor thesis
      Restricted access - confidentiality agreement
    • Influence of fibrosis in the genesis of atrial fibrillation: a simulation study in human atrial tissue 

      Xifra Esser, Carla (Universitat Politècnica de Catalunya, 2021-07-13)
      Bachelor thesis
      Open Access
      A dual analysis pretends to associate spontaneous calcium release events (SCRE) as rapid arrhythmia triggers and, atrial fibrosis, as a proper substrate for the perpetuation of atrial fibrillation. This computational study ...
    • Interpretabilitat de models d'aprenentatge profund en problemes de classificació d'imatges 

      Condom Tibau, Jordi Guillem (Universitat Politècnica de Catalunya, 2022-07)
      Bachelor thesis
      Open Access
      En aquest projecte s'ha desenvolupat un model d'aprenentatge profund per a la predicció d'uns fenòmens biofísics que es duen a terme a mes membranes de les cèl·lules cardíaques anomenats espícules de Calci. Depenent de com ...
    • Mathematical modeling of calcium handling dysfunctions leading to atrial fibrillation 

      Krizanec, Nikolina (Universitat Politècnica de Catalunya, 2017-10)
      Master thesis
      Open Access
      The aim of this master s thesis is to study the basic cardiac cellular electrophysiology in order to understand and examine the role of SK3 channels. Among the many channels present in an atrial myocyte, SK3 channels are ...
    • Mathematical modelling of the epidemic dynamics due to viral interference 

      Usán Sanz, Pablo (Universitat Politècnica de Catalunya, 2023-07-10)
      Master thesis
      Open Access
      Throughout this report we will study the substitution dynamics between two variants of SARS-CoV-19, more specifically the one who took place between Delta and Omicron BA.1 variants. To this effect, we develop two mathematical ...
    • Mètodes de control discrets per alternants cardíacs 

      Wieczorek I Masdeu, Nora (Universitat Politècnica de Catalunya, 2018-09)
      Bachelor thesis
      Open Access
      Els alternans són variacions periòdiques en el potencial d'acció de les cèl·lules cardíaques. Aquests poden provocar el pas del ritme normal del cor a la taquicàrdia e inclòs a la fibril·lació, amb la pèrdua de la capacitat ...
    • Modeling Human Atrial Electrodynamics and Arrhythmias through GPU Parallel Computing: From Cell to Tissue 

      Canal Noguer, Pol (Universitat Politècnica de Catalunya, 2016-07-01)
      Bachelor thesis
      Open Access
      Covenantee:   Georgia Institute of Technology
      The goal of this project is to study instabilities in human atrial cardiac tissue using a complex non-linear set of differential equations through GPU parallel computing. More specifically, the topic it focuses on is atrial ...
    • Modelling pathological effects in intracellular calcium dynamics leading to atrial fibrillation 

      Marchena Angos, Miquel (Universitat Politècnica de Catalunya, 2020-07-23)
      Doctoral thesis
      Open Access
      The heart beating is produced by the synchronization of the cardiac cells' contraction. A dysregulation in this mechanism may produce episodes of abnormal heart contraction. The origin of these abnormalities often lies at ...
    • Numerical model of cardiac electrochemistry 

      García Delgado, Ana (Universitat Politècnica de Catalunya, 2021-05)
      Bachelor thesis
      Open Access
      Given the relevance of cardiac maladies in today's society, investigation driven towards the understanding of how our hearts work has been gaining importance. In this bachelor degree thesis we approach the matter by giving ...
    • Numerical model of cardiac electromechanics 

      Wieczorek I Masdeu, Nora (Universitat Politècnica de Catalunya, 2019-10)
      Master thesis
      Open Access
      In this project, we develop a Finite Element Method (FEM) formulation that solves the cardiac electrophysiological problem of a three dimensional piece of tissue. This problem is modeled by an electromechanical model that ...
    • Origin of dynamic Nematic order in epethelial cell layers 

      Prol Castelo, Guillermo (Universitat Politècnica de Catalunya, 2019-07-09)
      Bachelor thesis
      Open Access
      Covenantee:   Technische Universität München
      Collective cell migration involves not only the need for cells to assemble into and sustain a certain architecture ? they must also coordinate their behaviors across space and time. Cells in a layer will arrange in different ...
    • Patient specific models of clotting 

      Ripoll Oliveras, Albert (Universitat Politècnica de Catalunya, 2018-05)
      Bachelor thesis
      Open Access
      Covenantee:   Massachusetts Institute of Technology. Clinical Research Center
      There is an increasing impact of cardiovascular diseases on the population worldwide that have lead them to be the first cause of global mortality. Most of these cardiovascular diseases evolve to high fatality rates when ...