Browsing by Author "Gómez Melis, Guadalupe"
Now showing items 1-20 of 86
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A class of two-sample nonparametric statistics for binary and time-to-event outcomes
Bofill Roig, Marta; Gómez Melis, Guadalupe (2022)
Article
Open AccessWe propose a class of two-sample statistics for testing the equality of proportions and the equality of survival functions. We build our proposal on a weighted combination of a score test for the difference in proportions ... -
A new approach for sizing trials with composite binary endpoints using anticipated marginal values and accounting for the correlation between components
Bofill Roig, Marta; Gómez Melis, Guadalupe (2019-05-20)
Article
Open AccessComposite binary endpoints are increasingly used as primary endpoints in clinical trials. When designing a trial, it is crucial to determine the appropriate sample size for testing the statistical differences between ... -
A nonparametric test for the association between longitudinal covariates and censored survival data
Oller Piqué, Ramón; Gómez Melis, Guadalupe (Oxford University Press, 2020-10-01)
Article
Open AccessMany biomedical studies focus on the association between a longitudinal measurement and a time-to-event outcome while quantifying this association by means of a longitudinal-survival joint model. In this article we propose ... -
A semi-parametric joint model for two sequential times to events and one longitudinal covariate
Serrat Piè, Carles; Abel Huertas, Jaime; Gómez Melis, Guadalupe (2012)
Conference lecture
Open AccessThe present work proposes a joint model for two sequential times to events together with longitudinal information, as an extension of the joint model by Wolfsohn and Tsiatis (1997) for one time to event and one longitudinal ... -
A shared-parameter joint model for prostate cancer risk and psa longitudinal profiles
Serrat Piè, Carles; Rué, Montserrat; Perpiñán Fabuel, Hèctor; Forte, Anabel; Armero, Carmen; Piulachs Lozada Benavente, Xavier; Páez, Álvaro; Gómez Melis, Guadalupe (Fundación Mapfre, 2015)
Conference report
Open AccessThe paper describes the use of frequentist and Bayesian shared-parameter joint models of longitudinal measurements of prostate specific antigen (PSA) and the risk of prostate cancer (PCa). The motivating dataset corresponds ... -
Advanced Statistical Inference
Gómez Melis, Guadalupe; Sánchez Pla, Àlex (Universitat Politècnica de Catalunya, 2017-01-11)
Exam
Restricted access to the UPC academic community -
Analyzing left-truncated and right-censored infectious disease cohort data with interval-censored infection onset
Pak, Daewoo; Liu, Jun; Ning, Jing; Gómez Melis, Guadalupe; Shen, Yu (2021-01-01)
Article
Open Accessn an infectious disease cohort study, individuals who have been infected with apathogenare often recruited for follow up. The period between infection and the onset of symptomatic disease, referred to as the incubation ... -
ANÀLISI DE LA SUPERVIVÈNCIA
Gómez Melis, Guadalupe (Universitat Politècnica de Catalunya, 2012-01-11)
Exam
Restricted access to the UPC academic community -
ANÀLISI DE LA SUPERVIVÈNCIA
Gómez Melis, Guadalupe (Universitat Politècnica de Catalunya, 2011-01-10)
Exam
Restricted access to the UPC academic community -
ANÀLISI DE TEMPS DE VIDA
Gómez Melis, Guadalupe (Universitat Politècnica de Catalunya, 2016-01-12)
Exam
Restricted access to the UPC academic community -
ANÀLISI DE TEMPS DE VIDA
Gómez Melis, Guadalupe (Universitat Politècnica de Catalunya, 2016-01-12)
Exam
Restricted access to the UPC academic community -
Association of premenopausal risk-reducing salpingo-oophorectomy with breast cancer risk in BRCA1/2 mutation carriers: maximising bias-reduction
Stjepanovic, Neda; Villacampa, Guillermo; Gómez Melis, Guadalupe (2020-06-01)
Article
Open AccessBackground. Whether risk-reducing salpingo-oophorectomy (RRSO) in BRCA1/2 carriers reduces the breast cancer (BC) risk is conflicting, potentially due to methodological issues of prior analysis. We analysed the association ... -
Bayesian joint ordinal and survival modeling for breast cancer risk assessment
Armero, Carmen; Forné, Carles; Rué, Montserrat; Forte Deltell, Anabel; Perpiñán Fabuel, Hèctor; Gómez Melis, Guadalupe; Bare Mañas, Maris (2016-12-10)
Article
Open AccessWe propose a joint model to analyze the structure and intensity of the association between longitudinal measurements of an ordinal marker and time to a relevant event. The longitudinal process is defined in terms of a ... -
Biometría: Estudios de supervivencia con datos no observados. Dificultades inherentes al enfoque paramétrico
Gómez Melis, Guadalupe; Serrat Piè, Carles (Institut d'Estadística de Catalunya, 1999)
Article
Open AccessA partir de una muestra de datos de supervivencia que contiene valores no observados en las covariantes de interés, presentamos una metodología que permite extraer toda la información contenida en covariantes completamente ... -
BioStatNet: an interdisciplinary biostatistics network
Bayarri García, María Jesús; Cadarso Suárez, Carmen; Durbán Reguera, María Luz; Gómez Melis, Guadalupe; López Fidalgo, Jesús; Martín Andrés, Antonio; Nuñez Antón, Vicente; Puig Casado, Pere (Sociedad de Estadística e Investigación Operativa (SEIO), 2012-06)
Article
Open AccessBiostatistics has become a major scientific component of biomedical research with a strong interdisciplinary basis. This endeavour is essentially interdisciplinary, therefore, training of future biostatisticians must ... -
Characteristics and outcomes by ceiling of care of subjects hospitalized with COVID-19 during four waves of the pandemic in a metropolitan area: a multicenter cohort study
Pallarès, Natàlia; Tebé Cordomí, Cristian; Abelenda Alonso, Gabriela; Rombauts, Alexander; Oriol, Isabel; Simonetti, Antonella F.; Rodríguez Molinero, Alejandro; Izquierdo Tugas, Elisenda; Díaz Brito, Vicens; Molist, Gemma; Gómez Melis, Guadalupe; Carratalà Fernández, Jordi; Videla Ces, Sebastián (Springer Nature, 2022-12-10)
Article
Open AccessIntroduction The profiles of patients with COVID-19 have been widely studied, but little is known about differences in baseline characteristics and in outcomes between subjects with a ceiling of care assigned at hospital ... -
Circulating carotenoids are associated with favorable lipid and fatty acid profiles in an older population at high cardiovascular risk
Marhuenda Muñoz, María; Domínguez López, Inés; Langohr, Klaus; Tresserra Rimbau, Anna; Martínez González, Miguel Ángel; Salas Salvado, Jordi; Corella Piquer, Dolores; Zomeño Fajardo, María Dolores; Martínez Hernández, José Alfredo; Alonso Gómez, Angel M.; Wärnberg, Julia; Vioque López, Jesús; Romaguera, Dora; López Miranda, José; Estruch Riba, Ramón; Tinahones, Francisco J.; Gómez Melis, Guadalupe (2022-09-29)
Article
Open AccessCarotenoid intake has been reported to be associated with improved cardiovascular health, but there is little information on actual plasma concentrations of these compounds as biomarkers of cardiometabolic risk. The objective ... -
Clinical trial designs using CompARE. An on-line exploratory tool for investigators
Gómez Mateu, Moisés; Gómez Melis, Guadalupe (2017-03)
Research report
Open AccessConclusions from randomized clinical trials (RCT) rely primarily on the primary endpoint (PE) chosen at the design stage of the study. There should generally be only one PE which should be able to provide the most clinically ... -
Competing risks methods
Porta Bleda, Núria; Gómez Melis, Guadalupe; Calle Rosingana, M. Luz; Malats i Riera, Núria (2007-12-10)
Research report
Open AccessCompeting risks data usually arises in studies in which the failure of an individual may be classified into one of k (k > 1) mutually exclusive causes of failure. When competing risks are present, classical survival analysis ... -
Covid-19: la malinterpretación de los datos de la pandemia daña la confianza del público
Saez Zafra, Marc; Figueiras Guzmán, Adolfo; Alustiza, Ainhoa; Fernández Martínez, Daniel; Cobo Valeri, Erik; Gómez Melis, Guadalupe; González Alastrué, José Antonio; Fonseca Casas, Pau; Cortés García, Claudio Ulises (2020-11-04)
Article
Open Access