Browsing by Author "Gómez Melis, Guadalupe"
Now showing items 1-20 of 79
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A class of two-sample nonparametric statistics for binary and time-to-event outcomes
(2022)
Article
Open AccessWe propose a class of two-sample statistics for testing the equality of proportions and the equality of survival functions. We build our proposal on a weighted combination of a score test for the difference in proportions ... -
A new approach for sizing trials with composite binary endpoints using anticipated marginal values and accounting for the correlation between components
(2019-05-20)
Article
Open AccessComposite binary endpoints are increasingly used as primary endpoints in clinical trials. When designing a trial, it is crucial to determine the appropriate sample size for testing the statistical differences between ... -
A nonparametric test for the association between longitudinal covariates and censored survival data
(Oxford University Press, 2020-10-01)
Article
Restricted access - publisher's policyMany biomedical studies focus on the association between a longitudinal measurement and a time-to-event outcome while quantifying this association by means of a longitudinal-survival joint model. In this article we propose ... -
A semi-parametric joint model for two sequential times to events and one longitudinal covariate
(2012)
Conference lecture
Open AccessThe present work proposes a joint model for two sequential times to events together with longitudinal information, as an extension of the joint model by Wolfsohn and Tsiatis (1997) for one time to event and one longitudinal ... -
A shared-parameter joint model for prostate cancer risk and psa longitudinal profiles
(Fundación Mapfre, 2015)
Conference report
Open AccessThe paper describes the use of frequentist and Bayesian shared-parameter joint models of longitudinal measurements of prostate specific antigen (PSA) and the risk of prostate cancer (PCa). The motivating dataset corresponds ... -
Advanced Statistical Inference
(Universitat Politècnica de Catalunya, 2017-01-11)
Exam
Restricted access to the UPC academic community -
Analyzing left-truncated and right-censored infectious disease cohort data with interval-censored infection onset
(2021-01-01)
Article
Open Accessn an infectious disease cohort study, individuals who have been infected with apathogenare often recruited for follow up. The period between infection and the onset of symptomatic disease, referred to as the incubation ... -
ANÀLISI DE LA SUPERVIVÈNCIA
(Universitat Politècnica de Catalunya, 2012-01-11)
Exam
Restricted access to the UPC academic community -
ANÀLISI DE LA SUPERVIVÈNCIA
(Universitat Politècnica de Catalunya, 2011-01-10)
Exam
Restricted access to the UPC academic community -
ANÀLISI DE TEMPS DE VIDA
(Universitat Politècnica de Catalunya, 2016-01-12)
Exam
Restricted access to the UPC academic community -
ANÀLISI DE TEMPS DE VIDA
(Universitat Politècnica de Catalunya, 2016-01-12)
Exam
Restricted access to the UPC academic community -
Association of premenopausal risk-reducing salpingo-oophorectomy with breast cancer risk in BRCA1/2 mutation carriers: maximising bias-reduction
(2020-06-01)
Article
Open AccessBackground. Whether risk-reducing salpingo-oophorectomy (RRSO) in BRCA1/2 carriers reduces the breast cancer (BC) risk is conflicting, potentially due to methodological issues of prior analysis. We analysed the association ... -
Bayesian joint ordinal and survival modeling for breast cancer risk assessment
(2016-12-10)
Article
Open AccessWe propose a joint model to analyze the structure and intensity of the association between longitudinal measurements of an ordinal marker and time to a relevant event. The longitudinal process is defined in terms of a ... -
Biometría: Estudios de supervivencia con datos no observados. Dificultades inherentes al enfoque paramétrico
(Institut d'Estadística de Catalunya, 1999)
Article
Open AccessA partir de una muestra de datos de supervivencia que contiene valores no observados en las covariantes de interés, presentamos una metodología que permite extraer toda la información contenida en covariantes completamente ... -
BioStatNet: an interdisciplinary biostatistics network
(Sociedad de Estadística e Investigación Operativa (SEIO), 2012-06)
Article
Open AccessBiostatistics has become a major scientific component of biomedical research with a strong interdisciplinary basis. This endeavour is essentially interdisciplinary, therefore, training of future biostatisticians must ... -
Clinical trial designs using CompARE. An on-line exploratory tool for investigators
(2017-03)
Research report
Open AccessConclusions from randomized clinical trials (RCT) rely primarily on the primary endpoint (PE) chosen at the design stage of the study. There should generally be only one PE which should be able to provide the most clinically ... -
Competing risks methods
(2007-12-10)
Research report
Open AccessCompeting risks data usually arises in studies in which the failure of an individual may be classified into one of k (k > 1) mutually exclusive causes of failure. When competing risks are present, classical survival analysis ... -
Covid-19: la malinterpretación de los datos de la pandemia daña la confianza del público
(2020-11-04)
Article
Open Access -
Decision tool and Sample Size Calculator for composite endpoints
(2020-01-10)
Article
Open AccessThis article considers the combination of two binary or two time-to-event endpoints to form the primary composite endpoint for leading a trial. • It discusses the relative efficiency of choosing a composite endpoint over ... -
Definition of the viral targets of protective HIV-1-specific T cell responses
(2011-12-07)
Article
Open AccessBackground: The efficacy of the CTL component of a future HIV-1 vaccine will depend on the induction of responses with the most potent antiviral activity and broad HLA class I restriction. However, current HIV vaccine ...
