Now showing items 1-9 of 9

    • Biomimetic versus sintered calcium phosphates: The in vitro behavior of osteoblasts and mesenchymal stem cells 

      Sadowska, Joanna Maria; Guillem Martí, Jordi; Montufar Jiménez, Edgar Benjamin; Español Pons, Montserrat; Ginebra Molins, Maria Pau (2017-12-01)
      Article
      Open Access
      © Copyright 2017, Mary Ann Liebert, Inc.The fabrication of calcium phosphates using biomimetic routes, namely, precipitation processes at body temperature, results in distinct features compared to conventional sintered ...
    • Effect of microstructural and chemical cues on the in vitro cell response to calcium phosphates 

      Sadowska, Joanna Maria (Universitat Politècnica de Catalunya, 2018-07-24)
      Doctoral thesis
      Open Access
      Bone has a natural ability to regenerate. However, it cannot bridge large defects without the additional help of a supporting material. Among the different synthetic bone grafts, calcium phosphates (CaPs) are excellent ...
    • Effect of nano-structural properties of biomimetic hydroxyapatite on osteoimmunomodulation 

      Sadowska, Joanna Maria; Wei, Fei; Guo, Jia; Guillem Martí, Jordi; Ginebra Molins, Maria Pau; Xiao, Yin (2018-10)
      Article
      Open Access
      Immune cells are sensitive to the microstructural and textural properties of materials. Tuning the structural features of synthetic bone grafts could be a valuable strategy to regulate the specific response of the immune ...
    • Impact of biomimicry in the design of osteoinductive bone substitutes: nanoscale matters 

      Barba Serrahima, Albert; Díez Escudero, Anna; Español Pons, Montserrat; Bonany Mariñosa, Mar; Sadowska, Joanna Maria; Guillem Martí, Jordi; Ohman, Caroline; Persson, Cecilia; Manzanares, Maria Cristina; Franch, Jordi; Ginebra Molins, Maria Pau (2019-01-01)
      Article
      Open Access
      Covenantee:   Universitat Autònoma de Barcelona / Uppsala universitet / Universitat de Barcelona. Departament de Patologia i Terapèutica Experimental / Institut de Bioenginyeria de Catalunya
      Bone apatite consists of carbonated calcium-deficient hydroxyapatite (CDHA) nanocrystals. Biomimetic routes allow fabricating synthetic bone grafts that mimic biological apatite. In this work, we explored the role of two ...
    • In vitro response of mesenchymal stem cells to biomimetic hydroxyapatite substrates: a new strategy to assess the effect of ion exchange 

      Sadowska, Joanna Maria; Guillem Martí, Jordi; Español Pons, Montserrat; Stähli, Christoph; Dobelin, Nicola; Ginebra Molins, Maria Pau (Elsevier, 2018-08)
      Article
      Open Access
      Biomaterials can interact with cells directly, that is, by direct contact of the cells with the material surface, or indirectly, through soluble species that can be released to or uptaken from the surrounding fluids. ...
    • Investigation of the behavior of various calcium phosphate material during in vitro cell culture 

      Sadowska, Joanna Maria (Universitat Politècnica de Catalunya, 2013-07)
      Master thesis (pre-Bologna period)
      Open Access
      The great acceptance of calcium phosphate materials in the biomedical field comes from their close similirity to the mineral phase of bone. This make CaPs excellent subtrates for bone regeneration applications. In spite ...
    • Osteoinduction by foamed and 3D-printed calcium phosphate scaffolds: effect of nanostructure and pore architecture 

      Barba Serrahima, Albert; Díez Escudero, Anna; Maazouz, Yassine; Rappe, K.; Español Pons, Montserrat; Montufar Jiménez, Edgar Benjamin; Bonany Mariñosa, Mar; Sadowska, Joanna Maria; Guillem Martí, Jordi; Ohman, Caroline; Persson, Cecilia; Manzanares, Maria Cristina; Franch Serracanta, Jordi; Ginebra Molins, Maria Pau (2017-12-06)
      Article
      Open Access
      Covenantee:   Universitat Autònoma de Barcelona. Departament de Medicina i Cirurgia Animal / Universitat de Barcelona. Departament de Patologia i Terapèutica Experimental
      Some biomaterials are osteoinductive, that is, they are able to trigger the osteogenic process by inducing the differentiation of mesenchymal stem cells to the osteogenic lineage. Although the underlying mechanism is still ...
    • The effect of biomimetic calcium deficient hydroxyapatite and sintered ß-tricalcium phosphate on osteoimmune reaction and osteogenesis 

      Sadowska, Joanna Maria; Wei, Fei; Guo, Jia; Guillem Martí, Jordi; Lin, Zhengmei; Ginebra Molins, Maria Pau; Xiao, Yin (Elsevier, 2019-09-15)
      Article
      Open Access
      Covenantee:   Institute of Health and Biomedical Innovation / Australia-China Centre for Tissue Engineering and Regenerative Medicine / Institut de Bioenginyeria de Catalunya
      Biomaterial implantation triggers inflammatory reactions. Understanding the effect of physicochemical features of biomaterials on the release of inflammatory cytokines from immune cells would be of great interest in view ...
    • The influence of physicochemical properties of biomimetic Hydroxyapatite on the in vitro behavior of endothelial progenitor cells and their interaction with mesenchymal stem cells 

      Sadowska, Joanna Maria; Guillem Martí, Jordi; Ginebra Molins, Maria Pau (2019-01-24)
      Article
      Open Access
      Calcium phosphate (CaP) substrates are successfully used as bone grafts due to their osteogenic properties. However, the influence of the physicochemical features of CaPs in angiogenesis is frequently neglected despite it ...