Now showing items 1-9 of 9

    • Association between viscoelastic characteristics and sputum colour in patients with bronchiectasis 

      Alcaraz Serrano, Victoria; Sanz Fraile, Héctor; Bueno Freire, Leticia; Farré, Ramon; Otero, Jorge; Vázquez, Nil; Rovira Ribalta, Nona; Oscanoa, Patricia; Torres, Antoni; Fernández Barat, Laia (2023-06)
      Article
      Open Access
      In this study, we have described for the first time an association between the SCC and the viscoelastic characteristics of sputum in bronchiectasis. Although rheology has been suggested as a useful differential biomarker ...
    • Biocompatible 3D printed yttria-stabilized zirconia parts using direct ink writing 

      Buj Corral, Irene; Sanz Fraile, Héctor; Tejo Otero, Aitor; Xuriguera Martin, Elena; Otero, Jorge (2024-01)
      Article
      Open Access
      Metals such as titanium or Cr-Co alloys have been the most widely used materials in biomedical applications that require high mechanical properties, like implants. However, these materials present the disadvantage of ...
    • Cell-Laden 3D hydrogels of type I collagen incorporating bacterial nanocellulose fibers 

      Malandain, Nanthilde; Sanz Fraile, Héctor; Farré, Ramon; Otero, Jorge; Roig, Anna; Laromaine Segué, Anna (American Chemical Society, 2023-09-18)
      Article
      Open Access
      There is a growing interest in developing natural hydrogel-based scaffolds to culture cells in a three-dimensional (3D) millieu that better mimics the in vivo cells' microenvironment. A promising approach is to use hydrogels ...
    • Characterization of 3D Printed Metal-PLA Composite Scaffolds for Biomedical Applications 

      Buj Corral, Irene; Sanz Fraile, Héctor; Ulldemolins, Anna; Tejo Otero, Aitor; Domínguez Fernandez, Alejandro; Almendros, Isaac; Otero, Jorge (Multidisciplinary Digital Publishing Institute (MDPI), 2022-07-05)
      Article
      Open Access
      Three-dimensional printing is revolutionizing the development of scaffolds due to their rapid-prototyping characteristics. One of the most used techniques is fused filament fabrication (FFF), which is fast and compatible ...
    • Characterization of bioinks prepared via gelifying extracellular matrix from decellularized porcine myocardia 

      Sanz Fraile, Héctor; Herranz Díez, Carolina; Ulldemolins, Anna; Falcones Olarte, Bryan; Almendros, Isaac; Gavara, Núria; Sunyer, Raimon; Farré, Ramon; Otero, Jorge (Multidisciplinary Digital Publishing Institute (MDPI), 2023-09-13)
      Article
      Open Access
      Since the emergence of 3D bioprinting technology, both synthetic and natural materials have been used to develop bioinks for producing cell-laden cardiac grafts. To this end, extracellular-matrix (ECM)-derived hydrogels ...
    • Effects of aging on the biomechanical properties of the lung extracellular matrix: dependence on tissular stretch 

      Ulldemolins, Anna; Narciso, Maria; Sanz Fraile, Héctor; Otero, Jorge; Farré Ventura, Ramon; Gavara, Núria; Almendros, Isaac (Frontiers Media SA, 2024-04-05)
      Article
      Open Access
      Introduction: Aging induces functional and structural changes in the lung, characterized by a decline in elasticity and diminished pulmonary remodeling and regenerative capacity. Emerging evidence suggests that most ...
    • Involvement of mechanical cues in the migration of Cajal-Retzius cells in the marginal zone during neocortical development 

      López Mengual, Ana; Segura Feliu, Miriam; Sunyer, Raimon; Sanz Fraile, Héctor; Otero, Jorge; Mesquina Veny, Francina; Gil, Vanessa; Hervera, Arnau; Ferrer, Isidre; Soriano, Jordi; Trepat Guixer, Xavier; Farré, Ramon; Navajas Navarro, Daniel; Del Río, José Antonio (Frontiers Media SA, 2022-05-16)
      Article
      Open Access
      Emerging evidence points to coordinated action of chemical and mechanical cues during brain development. At early stages of neocortical development, angiogenic factors and chemokines such as CXCL12, ephrins, and semaphorins ...
    • Mechanical ventilation promotes lung tumour spread by modulation of cholesterol cell content 

      López Alonso, Inés; López Martínez, Cecilia; Martín Vicente, Paula; Amado Rodríguez, Laura; González López, Adrián; Mayordomo Colunga, Juan; del Busto, Cecilia; Bernal, Marina; Crespo, Irene; Astudillo, Aurora; Arias Guillén, Miguel; Fueyo, Antonio; Almendros, Isaac; Otero, Jorge; Sanz Fraile, Héctor; Farré, Ramon; Albaiceta, Guillermo M. (2022-07)
      Article
      Open Access
      Background: Mechanical stretch of cancer cells can alter their invasiveness. During mechanical ventilation, lungs may be exposed to an increased amount of stretch, but the consequences on lung tumours have not been explored. ...
    • Silk-reinforced collagen hydrogels with raised multiscale stiffness for mesenchymal cells 3D culture 

      Sanz Fraile, Héctor; Amorós García de Valdecasas, Susana; Mendizabal, Irene; Galvez Monton, Carolina; Prat Vidal, Cristina; Bayés Genis, Antoni; Navajas Navarro, Daniel; Farré Ventura, Ramon; Otero, Jordi (2020-03-01)
      Article
      Open Access
      Type I collagen hydrogels are of high interest in tissue engineering. With the evolution of 3D bioprinting technologies, a high number of collagen-based scaffolds have been reported for the development of 3D cell cultures. ...