Browsing by Author "Francesko, Antonio"
Now showing items 1-20 of 24
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Bacteria-responsive multilayer coatings comprising polycationic nanospheres for bacteria biofilm prevention on urinary catheters
(2016-01-21)
Article
Open AccessThis work reports on the development of infection-preventive coatings on silicone urinary catheters that contain in their structure and release on demand antibacterial polycationic nanospheres. Polycationic aminocellulose ... -
Bottom-up layer-by-layer assembling of antibacterial freestanding nanobiocomposite films
(2018-07-27)
Article
Open AccessIn this study, freestanding nanobiocomposite films were obtained by the sequential deposition of biopolymer-capped silver nanoparticles (AgNPs) and hyaluronic acid (HA). At first, dispersions ofAgNPs decorated with chitosan ... -
Effect of thiol-functionalisation on chitosan antibacterial activity: interaction with a bacterial membrane model
(2013-01-12)
Article
Restricted access - publisher's policyThe antibacterial activity of chitosan modified with the thiol-containing 2-iminothiolane HCl (TC-IMI) and N-acetyl- L -cysteine (TC-NAC) was studied by Langmuir film balance technique using a dipalmitoylphos- phatidylglycerol ... -
Enzymatic functionalization of cork surface with antimicrobial hybrid biopolymer/silver nanoparticles
(2015-05-13)
Article
Open AccessLaccase-assisted assembling of hybrid biopolymer-silver nanoparticles and cork matrices into an antimicrobial material with potential for water remediation is herein described. Amino-functional biopolymers were first used ... -
Enzyme-assisted formation of hybrid biopolymer hydrogels incorporating active phenolic nanospheres
(2015-02-01)
Article
Restricted access - publisher's policyThis work is about the synthesis of hybrid nanocomposite hydrogels comprising a thiolated chitosan platform that incorporates epigallocatechin gallate nanospheres as active polyphenolic agents for wound healing applications. ... -
Escherichia coli and pseudomonas aeruginosa eradication by nano-penicillin G
(2016-06-09)
Article
Open AccessThe transformation of penicillin G into nano/micro-sized spheres (nanopenicillin) using sonochemical technology was explored as a novel tool for the eradication of Gram-negative bacteria and their biofilms. Known by its ... -
Functional biopolymer-based matrices for modulation of chronic wound enzyme activities
(2012-10-13)
Article
Restricted access - publisher's policyCollagen, collagen/hyaluronic acid (HA) and collagen/HA/chitosan (CS) sponges loaded with epigallocatechin gallate (EGCG), catechin (CAT) and gallic acid (GA) were developed and evaluated as active chronic wound dressings. ... -
GAGs-thiolated chitosan assemblies for chronic wounds treatment: control of enzyme activity and cell attachment
(2012-04-20)
Article
Restricted access - publisher's policyMultilayered polyelectrolyte coatings comprising thiolated chitosan (TC) and glycosaminoglycans (GAGs), chondroitin sulphate and hyaluronic acid, were built using a layer-by-layer approach. The surface activity of these ... -
Hybrid chitosan-silver nanoparticles enzymatically-embedded on cork filter material for water disinfection
(2017-04-05)
Article
Restricted access - publisher's policyMicrobial contamination remains a major challenge in supply of drinking water in developing regions, despite the continuous advances being made in water purification processes. The spread and transmission of pathogens due ... -
Hydrogel dressings for advanced wound management
(2018-12)
Article
Open AccessComposed in a large extent of water and due to their non-adhesiveness, hydrogels found their way to the wound dressing market as materials that provide a moisture environment for healing while being comfortable to the ... -
Immobilization of antimicrobial core-shell nanospheres onto silicone for prevention of Escherichia coli biofilm formation
(2016-09-16)
Article
Open AccessEscherichia coli (E. coli) strains are among the most frequently isolated microorganisms in urinary tract infections able to colonize the surface of urinary catheters and form biofilms. These biofilms are highly resistant ... -
Inhibition of deleterious chronic wound enzymes with plant polyphenols
(2012-01-18)
Article
Restricted access - publisher's policyThe chronic wound environment is characterized by high concentrations of reactive oxygen species (ROS) and elevated levels of myeloperoxidase (MPO) and collagenases, together impairing the healing process. Therefore, the ... -
Laccase-assisted formation of bioactive chitosan/gelatin hydrogel stabilized with plant polyphenols
(2012-11-02)
Article
Restricted access - publisher's policyLaccase-assisted simultaneous cross-linking and functionalization of chitosan/gelatin blends with phenolic compounds from Hamamelis virginiana was investigated for the development of bioactive hydrogel dressings. The ... -
Multifuncional biopolymer-bases materials for modulatig the activites of chromic wound enzymes
(Universitat Politècnica de Catalunya, 2012-11-29)
Doctoral thesis
Open AccessThis thesis focuses on the development of active multifunctional dressing materials and nanoparticle formulations with suitable exploitation characteristics for chronic wounds treatment. Chronic wounds a growing clinical ... -
Nanotransformation of vancomycin overcomes the intrinsic resistance of Gram-negative bacteria
(2017-04-10)
Article
Open AccessThe increased emergence of antibiotic-resistant bacteria is a growing public health concern, and although new drugs are constantly being sought, the pace of development is slow compared with the evolution and spread of ... -
One-step sonochemical preparation of redox-responsive nanocapsules for glutathione mediated RNA release
(Royal Society of Chemistry, 2014-07-09)
Article
Restricted access - publisher's policyEfficient RNA delivery to targeted cells requires the use of stable interactive carriers that provide RNA protection during the extracellular transit and trigger release once internalised. One strategy to avoid the premature ... -
Quorum-quenching and matrix-degrading enzymes in multilayer coatings synergistically prevent bacterial biofilm formation on urinary catheters
(2015-12-02)
Article
Open AccessBacteria often colonize in-dwelling medical devices and grow as complex biofilm communities of cells embedded in a self-produced extracellular polymeric matrix, which increases their resistance to antibiotics and the host ... -
Sensor materials for the detection of human neutrophil elastase and cathepsin G activity in wound ¿uid
(2011-04-13)
Article
Restricted access - publisher's policyHuman neutrophil elastase (HNE) and cathepsin G (CatG) are involved in the pathogenesis of a number of inflammatory disorders. These serine proteinases are released by neutrophils and monocytes in case of infection. Wound ... -
Simultaneous sonochemical-enzymatic coating of medical textiles with antibacterial ZnO nanoparticles
(2016-03-01)
Article
Open AccessThe antimicrobial finishing is a must for production of medical textiles, aiming at reducing the bioburden in clinical wards and consequently decreasing the risk of hospital-acquired infections. This work reports for the ... -
Size and aging effects on antimicrobial efficiency of silver nanoparticles coated on polyamide fabrics activated by atmospheric DBD plasma
(2015-06-09)
Article
Open AccessThis work studies the surface characteristics, antimicrobial activity, and aging effect of plasma-pretreated polyamide 6,6 (PA66) fabrics coated with silver nanoparticles (AgNPs), aiming to identify the optimum size of ...
