Now showing items 1-9 of 9

    • Cell-centred model for non-linear tissue rheology and active remodelling 

      Asadipour, Nina; Mosaffa, Payman; Muñoz Romero, José (Centre Internacional de Mètodes Numèrics en Enginyeria (CIMNE), 2014)
      Conference report
      Restricted access - publisher's policy
      Soft active tissues exhibit softening, hardening, and reversible fluidisation. The result of these non-linear behaviour is due to multiple processes taking part at different scales: active protein motors that actuate at ...
    • Cell-centred model for the simulation of curved cellular monolayers 

      Mosaffa, Payman; Asadipour, Nina; Millán, Raúl Daniel; Rodríguez Ferran, Antonio; Muñoz Romero, José (2015)
      Article
      Open Access
      This paper presents a cell-centred model for the simulation of planar and curved multicellular soft tissues. We propose a computational model that includes stress relaxation due to cell reorganisation (intercellular ...
    • Computational tools for multicellular systems 

      Muñoz Primer, Jose J.; Mosaffa, Payman; Asadipour, Nina; Conte, Vito (EUETIB, 2014-12-01)
      Conference report
      Open Access
      Macroscopic deformations in embryonic soft tissues are due to the intra-cellular remodelling and cell intercalation. We here present a computational approach that can handle the two types of deformations, and also take ...
    • Hybrid cell centred/vertex model for cellular nanolayers 

      Mosaffa, Payman; Asadipour, Nina; Millán, Daniel; Rodríguez Ferran, Antonio; Muñoz Romero, José (2015)
      Conference report
      Open Access
      Macroscopic deformations in embryonic soft tissues are due to the intra-cellular remodelling and cell intercalation. We here present a computational approach that can handle the two types of deformations, and also take ...
    • Hybrid cell centred/vertex model for large tissue deformations 

      Muñoz Romero, José; Mosaffa, Payman; Mao, Yanlan; Tetley, Rob; Asadipour, Nina; Rodríguez Ferran, Antonio (2016)
      Conference report
      Open Access
      Macroscopic deformations in embryonic soft tissues are due to the intra-cellular remodelling and cell intercalation. We here present a computational approach that can handle the two types of deformations, and also take ...
    • Hybrid cell-centred/vertex model for multicellular systems 

      Mosaffa, Payman (Universitat Politècnica de Catalunya, 2017-11-11)
      Doctoral thesis
      Open Access
      This thesis presents a hybrid vertex/cell-centred approach to mechanically simulate planar cellular monolayers undergoing cell reorganisation. Cell centres are represented by a triangular nodal network, while the cell ...
    • Hybrid cell-centred/vertex model for multicellular systems with equilibrium-preserving remodelling 

      Mosaffa, Payman; Rodríguez Ferran, Antonio; Muñoz Romero, José (John Wiley & sons, 2018-03)
      Article
      Open Access
      We present a hybrid vertex/cell-centred model for mechanically simulating planar cellular monolayers undergoing cell reorganisation. Cell centres are represented by a triangular nodal network, while the cell boundaries are ...
    • Junctional and cytoplasmic contributions in wound healing 

      Mosaffa, Payman; Tetley, Rob; Rodríguez Ferran, Antonio; Mao, Yanlan; Muñoz Romero, José (2020-08-26)
      Article
      Open Access
      Wound healing is characterized by the re-epitheliation of a tissue through the activation of contractile forces concentrated mainly at the wound edge. While the formation of an actin purse string has been identified as one ...
    • Stress relaxation in epithelial monolayers is controlled by the actomyosin cortex 

      Khalilgharibi, Nargess; Fouchard, Jonathan; Asadipour, Nina; Barrientos, Ricardo; Duda, Maria; Bonfanti, Alessandra; Yonis, Amina; Harris, Andrew; Mosaffa, Payman; Fujita, Yasuyuki; Kabla, Alexandre; Mao, Yanlan; Baum, Buzz; Muñoz Romero, José; Miodownik, Mark; Charras, Guillaume (2019-01-01)
      Article
      Open Access
      Epithelial monolayers are one-cell thick tissue sheets that separate internal and external environments. As part of their function, they have to withstand extrinsic mechanical stresses applied at high strain rates. However, ...