Now showing items 1-19 of 19

  • Bioceramics and bone healing 

    Ginebra Molins, Maria Pau; Español Pons, Montserrat; Maazouz, Yassine; Bergez, Victor; Pastorino Carraz, David (2018-05-01)
    Article
    Open Access
    - Calcium phosphates have long been used as synthetic bone grafts. Recent studies have shown that the modulation of composition and textural properties, such as nano-, micro- and macro-porosity, is a powerful strategy to ...
  • Biomimetic versus sintered calcium phosphates: The in vitro behavior of osteoblasts and mesenchymal stem cells 

    Sadowska, Joanna Maria; Guillem Martí, Jordi; Montufar Jiménez, Edgar Benjamin; Español Pons, Montserrat; Ginebra Molins, Maria Pau (2017-12-01)
    Article
    Open Access
    © Copyright 2017, Mary Ann Liebert, Inc.The fabrication of calcium phosphates using biomimetic routes, namely, precipitation processes at body temperature, results in distinct features compared to conventional sintered ...
  • Calcium phosphate cements as drug delivery materials 

    Ginebra Molins, Maria Pau; Canal Barnils, Cristina; Español Pons, Montserrat; Pastorino, David; Montufar Jiménez, Edgar Benjamin (2012-01-25)
    Article
    Restricted access - publisher's policy
    Calcium phosphate cements are used as synthetic bone grafts, with several advantages, such as their osteoconductivity and injectability. Moreover, their low-temperature setting reaction and intrinsic porosity allow for the ...
  • Design strategies for biomimetic bone implants from calcium phosphate cements (Part 1) 

    Canal Barnils, Cristina; Español Pons, Montserrat; Ginebra Molins, Maria Pau (2016)
    Article
    Restricted access - publisher's policy
  • Design strategies for biomimetic bone implants from calcium phosphate cements (Part II) 

    Canal Barnils, Cristina; Español Pons, Montserrat; Ginebra Molins, Maria Pau (2016)
    Article
    Restricted access - publisher's policy
  • Effects of molecular weight and concentration of poly(acrylic acid) on biomimetic mineralization of collagen 

    Qi, Yipin; Ye, Zhou; Fok, Alex; Holmes, Brian N.; Español Pons, Montserrat; Ginebra Molins, Maria Pau; Aparicio Badenas, Conrado José (American Chemical Society (ACS), 2018-06-29)
    Article
    Restricted access - publisher's policy
    Inspired by nature, poly(acrylic acid) (PAA) and other polyelectrolytes have been used as noncollagenous proteins (NCPs) surrogates for biomimetic intrafibrillar mineralization of collagen fibrils and, thus, to model the ...
  • Focus ion beam/scanning electron microscopy characterization of osteoclastic resorption of calcium phosphate substrates 

    Díez Escudero, Anna; Español Pons, Montserrat; Montufar Jiménez, Edgar Benjamin; Pompo, Gemma di; Ciapetti, Gabriela; Baldini, Nicola; Ginebra Molins, Maria Pau (2017-02-01)
    Article
    Open Access
    Covenantee:  Istituto Ortopedico Rizzoli
    This article presents the application of dual focused ion beam/scanning electron microscopy (FIB-SEM) imaging for preclinical testing of calcium phosphates with osteoclast precursor cells and how this high-resolution imaging ...
  • Formation of calcium phosphate nanostructures under the influence of self-assembling hybrid elastin-like-statherin recombinamers 

    Hamed Misbah, M.; Español Pons, Montserrat; Quintanilla, Luis; Ginebra Molins, Maria Pau; Rodriguez Cabello, Jose Carlos (2016-01-01)
    Article
    Open Access
    Covenantee:  Universidad de Valladolid
    The self-assembling properties of thermally-sensitive amphiphilic elastin-like multiblock recombinamers have been combined with the capacities of calcium phosphate binding of the SN(A)15 epitope inspired by the salivary ...
  • Heparinization of beta tricalcium phosphate: osteo-immunomodulatory effects 

    Díez Escudero, Anna; Español Pons, Montserrat; Bonany Mariñosa, Mar; Persson, Cecilia; Ginebra Molins, Maria Pau (2018-03-07)
    Article
    Open Access
    Immune cells play a vital role in regulating bone dynamics. This has boosted the interest in developing biomaterials that can modulate both the immune and skeletal systems. In this study, calcium phosphates discs (i.e., ...
  • Impact of porosity and electrolyte composition on the surface charge of hydroxyapatite biomaterials 

    Español Pons, Montserrat; Ginebra Molins, Maria Pau; Dory, Jean Baptiste (-, 2015-12-18)
    Article
    Open Access
    The success or failure of a material when implanted in the body is greatly determined by the surface properties of the material and the host tissue reactions. The very first event that takes place after implantation is the ...
  • Inflammatory response to nano- and microstructured hydroxyapatite 

    Mestres, Gemma; Español Pons, Montserrat; xia, wei; Persson, Cecilia; Ginebra Molins, Maria Pau; Karlsson Ott, Marjam (2015-04-02)
    Article
    Open Access
    The proliferation and activation of leukocytes upon contact with a biomaterial play a crucial role in the degree of inflammatory response, which may then determine the clinical failure or success of an implanted biomaterial. ...
  • In vitro degradation of calcium phosphates: Effect of multiscale porosity, textural properties and composition 

    Díez Escudero, Anna; Español Pons, Montserrat; Beats, Sean; Ginebra Molins, Maria Pau (2017-09-15)
    Article
    Open Access
    The capacity of calcium phosphates to be replaced by bone is tightly linked to their resorbability. However, the relative importance of some textural parameters on their degradation behavior is still unclear. The present ...
  • In vitro response of mesenchymal stem cells to biomimetic hydroxyapatite substrates: a new strategy to assess the effect of ion exchange 

    Sadowska, Joanna Maria; Guillem Martí, Jordi; Español Pons, Montserrat; Stähli, Christoph; Dobelin, Nicola; Ginebra Molins, Maria Pau (Elsevier, 2018-08)
    Article
    Open Access
    Biomaterials can interact with cells directly, that is, by direct contact of the cells with the material surface, or indirectly, through soluble species that can be released to or uptaken from the surrounding fluids. ...
  • Ion-doping as a strategy to modulate hydroxyapatite nanoparticle internalization 

    Zhao, Zhitong; Español Pons, Montserrat; Guillem Martí, Jordi; Kempf, Doreen; Díez Escudero, Anna; Ginebra Molins, Maria Pau (2016)
    Article
    Open Access
    Although it is widely acknowledged that ionic substitutions on bulk hydroxyapatite substrates have a strong impact on their biological performance, little is known of their effect on nanoparticles (NPs) especially when ...
  • New processing approaches in calcium phosphate cements and their applications in regenerative medicine 

    Ginebra Molins, Maria Pau; Español Pons, Montserrat; Montufar Jiménez, Edgar Benjamin; Pérez, R. A.; Mestres Beà, Gemma (2010-08)
    Article
    Restricted access - publisher's policy
    The key feature of calcium phosphate cements (CPCs) lies in the setting reaction triggered by mixing one or more solid calcium phosphate salts with an aqueous solution. Upon mixture, the reaction takes place through a ...
  • Occurrence of Pasteuria spp. in the northeastern Spain 

    Verdejo Lucas, Soledad; Español Pons, Montserrat; Ornat Longarón, Cèsar; Sorribas Royo, Francisco Javier (1997)
    Article
    Open Access
    The occurrence of Pasteuria spp. In Spanish oils is reported. A total of 160 soil samples were collected from vegetable crops, kiwi and citrus orchards, and deciduous fruit trees. Bacteria were found associated with six ...
  • Osteogenesis by foamed and 3D-printed nanostructured calcium phosphate scaffolds: Effect of pore architecture 

    Barba, Albert; Maazouz, Yassine; Díez Escudero, Anna; Español Pons, Montserrat; Montufar Jiménez, Edgar Benjamin; Ginebra Molins, Maria Pau (Elsevier, 2018-10-01)
    Article
    Restricted access - publisher's policy
    There is an urgent need of synthetic bone grafts with enhanced osteogenic capacity. This can be achieved by combining biomaterials with exogenous growth factors, which however can have numerous undesired side effects, but ...
  • Osteoinduction by foamed and 3D-printed calcium phosphate scaffolds: effect of nanostructure and pore architecture 

    Barba Serrahima, Albert; Díez Escudero, Anna; Maazouz, Yassine; Rappe, K.; Español Pons, Montserrat; Montufar Jiménez, Edgar Benjamin; Bonany Mariñosa, Mar; Sadowska, Joanna Maria; Guillem Martí, Jordi; Ohman, Caroline; Persson, Cecilia; Manzanares, Maria Cristina; Franch Serracanta, Jordi; Ginebra Molins, Maria Pau (2017-12-06)
    Article
    Open Access
    Covenantee:  Universitat Autònoma de Barcelona. Departament de Medicina i Cirurgia Animal / Universitat de Barcelona. Departament de Patologia i Terapèutica Experimental
    Some biomaterials are osteoinductive, that is, they are able to trigger the osteogenic process by inducing the differentiation of mesenchymal stem cells to the osteogenic lineage. Although the underlying mechanism is still ...
  • Self-hardening and thermoresponsive alpha tricalcium phosphate/pluronic pastes 

    Maazouz, Yassine; Montufar Jiménez, Edgar Benjamin; Malbert, Julien; Español Pons, Montserrat; Ginebra Molins, Maria Pau (2017-02)
    Article
    Open Access
    Although calcium phosphate cements (CPCs) are used for bone regeneration in a wide range of clinical applications, various physicochemical phenomena are known to hinder their potential use in minimally invasive surgery or ...