Now showing items 1-20 of 22

    • Bioceramics and bone healing 

      Ginebra Molins, Maria Pau; Español Pons, Montserrat; Maazouz, Yassine; Bergez, Victor; Pastorino Carraz, David (2018-05-01)
      Article
      Open Access
      - Calcium phosphates have long been used as synthetic bone grafts. Recent studies have shown that the modulation of composition and textural properties, such as nano-, micro- and macro-porosity, is a powerful strategy to ...
    • Biomimetic versus sintered calcium phosphates: The in vitro behavior of osteoblasts and mesenchymal stem cells 

      Sadowska, Joanna Maria; Guillem Martí, Jordi; Montufar Jiménez, Edgar Benjamin; Español Pons, Montserrat; Ginebra Molins, Maria Pau (2017-12-01)
      Article
      Open Access
      © Copyright 2017, Mary Ann Liebert, Inc.The fabrication of calcium phosphates using biomimetic routes, namely, precipitation processes at body temperature, results in distinct features compared to conventional sintered ...
    • Calcium phosphate cements as drug delivery materials 

      Ginebra Molins, Maria Pau; Canal Barnils, Cristina; Español Pons, Montserrat; Pastorino, David; Montufar Jiménez, Edgar Benjamin (2012-01-25)
      Article
      Restricted access - publisher's policy
      Calcium phosphate cements are used as synthetic bone grafts, with several advantages, such as their osteoconductivity and injectability. Moreover, their low-temperature setting reaction and intrinsic porosity allow for the ...
    • Design strategies for biomimetic bone implants from calcium phosphate cements (Part 1) 

      Canal Barnils, Cristina; Español Pons, Montserrat; Ginebra Molins, Maria Pau (2016)
      Article
      Restricted access - publisher's policy
    • Design strategies for biomimetic bone implants from calcium phosphate cements (Part II) 

      Canal Barnils, Cristina; Español Pons, Montserrat; Ginebra Molins, Maria Pau (2016)
      Article
      Restricted access - publisher's policy
    • EDTA and NTA effectively tune the mineralization of calcium phosphate from bulk aqueous solution 

      Hentrich, Doreen; Tauer, Klaus; Español Pons, Montserrat; Ginebra Molins, Maria Pau; Taubert, Andreas (2017-12-01)
      Article
      Open Access
      Covenantee:   Universität Potsdam / Max-Planck-Institut für Kolloid- und Grenzflächenforschung
      This study describes the effects of nitrilotriacetic acid (NTA) and ethylenediaminotetraacetic acid (EDTA) on the mineralization of calcium phosphate from bulk aqueous solution. Mineralization was performed between pH 6 ...
    • Effect of calcium phosphate heparinization on the in vitro inflammatory response and osteoclastogenesis of human blood precursor cells 

      Díez Escudero, Anna; Torreggiani, E.; Pompo, Gemma di; Español Pons, Montserrat; Persson, Cecilia; Ciapetti, Gabriela; Baldini, Nicola; Ginebra Molins, Maria Pau (2019-01-01)
      Article
      Open Access
      Covenantee:   Istituto Ortopedico Rizzoli / Uppsala universitet / Università di Bologna / Institut de Bioenginyeria de Catalunya
      The immobilization of natural molecules on synthetic bone grafts stands as a strategy to enhance their biological interactions. During the early stages of healing, immune cells and osteoclasts (OC) modulate the inflammatory ...
    • Effects of molecular weight and concentration of poly(acrylic acid) on biomimetic mineralization of collagen 

      Qi, Yipin; Ye, Zhou; Fok, Alex; Holmes, Brian N.; Español Pons, Montserrat; Ginebra Molins, Maria Pau; Aparicio Badenas, Conrado José (American Chemical Society (ACS), 2018-06-29)
      Article
      Restricted access - publisher's policy
      Inspired by nature, poly(acrylic acid) (PAA) and other polyelectrolytes have been used as noncollagenous proteins (NCPs) surrogates for biomimetic intrafibrillar mineralization of collagen fibrils and, thus, to model the ...
    • Focus ion beam/scanning electron microscopy characterization of osteoclastic resorption of calcium phosphate substrates 

      Díez Escudero, Anna; Español Pons, Montserrat; Montufar Jiménez, Edgar Benjamin; Pompo, Gemma di; Ciapetti, Gabriela; Baldini, Nicola; Ginebra Molins, Maria Pau (2017-02-01)
      Article
      Open Access
      Covenantee:   Istituto Ortopedico Rizzoli
      This article presents the application of dual focused ion beam/scanning electron microscopy (FIB-SEM) imaging for preclinical testing of calcium phosphates with osteoclast precursor cells and how this high-resolution imaging ...
    • Formation of calcium phosphate nanostructures under the influence of self-assembling hybrid elastin-like-statherin recombinamers 

      Hamed Misbah, M.; Español Pons, Montserrat; Quintanilla, Luis; Ginebra Molins, Maria Pau; Rodriguez Cabello, Jose Carlos (2016-01-01)
      Article
      Open Access
      Covenantee:   Universidad de Valladolid
      The self-assembling properties of thermally-sensitive amphiphilic elastin-like multiblock recombinamers have been combined with the capacities of calcium phosphate binding of the SN(A)15 epitope inspired by the salivary ...
    • Heparinization of beta tricalcium phosphate: osteo-immunomodulatory effects 

      Díez Escudero, Anna; Español Pons, Montserrat; Bonany Mariñosa, Mar; Persson, Cecilia; Ginebra Molins, Maria Pau (2018-03-07)
      Article
      Open Access
      Immune cells play a vital role in regulating bone dynamics. This has boosted the interest in developing biomaterials that can modulate both the immune and skeletal systems. In this study, calcium phosphates discs (i.e., ...
    • Impact of biomimicry in the design of osteoinductive bone substitutes: nanoscale matters 

      Barba Serrahima, Albert; Díez Escudero, Anna; Español Pons, Montserrat; Bonany Mariñosa, Mar; Sadowska, Joanna Maria; Guillem Martí, Jordi; Ohman, Caroline; Persson, Cecilia; Manzanares, Maria Cristina; Franch, Jordi; Ginebra Molins, Maria Pau (2019-01-01)
      Article
      Open Access
      Covenantee:   Universitat Autònoma de Barcelona / Uppsala universitet / Universitat de Barcelona. Departament de Patologia i Terapèutica Experimental / Institut de Bioenginyeria de Catalunya
      Bone apatite consists of carbonated calcium-deficient hydroxyapatite (CDHA) nanocrystals. Biomimetic routes allow fabricating synthetic bone grafts that mimic biological apatite. In this work, we explored the role of two ...
    • Impact of porosity and electrolyte composition on the surface charge of hydroxyapatite biomaterials 

      Español Pons, Montserrat; Ginebra Molins, Maria Pau; Dory, Jean Baptiste (-, 2015-12-18)
      Article
      Open Access
      The success or failure of a material when implanted in the body is greatly determined by the surface properties of the material and the host tissue reactions. The very first event that takes place after implantation is the ...
    • In vitro degradation of calcium phosphates: Effect of multiscale porosity, textural properties and composition 

      Díez Escudero, Anna; Español Pons, Montserrat; Beats, Sean; Ginebra Molins, Maria Pau (2017-09-15)
      Article
      Open Access
      The capacity of calcium phosphates to be replaced by bone is tightly linked to their resorbability. However, the relative importance of some textural parameters on their degradation behavior is still unclear. The present ...
    • In vitro response of mesenchymal stem cells to biomimetic hydroxyapatite substrates: a new strategy to assess the effect of ion exchange 

      Sadowska, Joanna Maria; Guillem Martí, Jordi; Español Pons, Montserrat; Stähli, Christoph; Dobelin, Nicola; Ginebra Molins, Maria Pau (Elsevier, 2018-08)
      Article
      Open Access
      Biomaterials can interact with cells directly, that is, by direct contact of the cells with the material surface, or indirectly, through soluble species that can be released to or uptaken from the surrounding fluids. ...
    • Inflammatory response to nano- and microstructured hydroxyapatite 

      Mestres, Gemma; Español Pons, Montserrat; xia, wei; Persson, Cecilia; Ginebra Molins, Maria Pau; Karlsson Ott, Marjam (2015-04-02)
      Article
      Open Access
      The proliferation and activation of leukocytes upon contact with a biomaterial play a crucial role in the degree of inflammatory response, which may then determine the clinical failure or success of an implanted biomaterial. ...
    • Ion-doping as a strategy to modulate hydroxyapatite nanoparticle internalization 

      Zhao, Zhitong; Español Pons, Montserrat; Guillem Martí, Jordi; Kempf, Doreen; Díez Escudero, Anna; Ginebra Molins, Maria Pau (2016)
      Article
      Open Access
      Although it is widely acknowledged that ionic substitutions on bulk hydroxyapatite substrates have a strong impact on their biological performance, little is known of their effect on nanoparticles (NPs) especially when ...
    • New processing approaches in calcium phosphate cements and their applications in regenerative medicine 

      Ginebra Molins, Maria Pau; Español Pons, Montserrat; Montufar Jiménez, Edgar Benjamin; Pérez, R. A.; Mestres Beà, Gemma (2010-08)
      Article
      Restricted access - publisher's policy
      The key feature of calcium phosphate cements (CPCs) lies in the setting reaction triggered by mixing one or more solid calcium phosphate salts with an aqueous solution. Upon mixture, the reaction takes place through a ...
    • Occurrence of Pasteuria spp. in the northeastern Spain 

      Verdejo Lucas, Soledad; Español Pons, Montserrat; Ornat Longarón, Cèsar; Sorribas Royo, Francisco Javier (1997)
      Article
      Open Access
      The occurrence of Pasteuria spp. In Spanish oils is reported. A total of 160 soil samples were collected from vegetable crops, kiwi and citrus orchards, and deciduous fruit trees. Bacteria were found associated with six ...
    • Osteogenesis by foamed and 3D-printed nanostructured calcium phosphate scaffolds: Effect of pore architecture 

      Barba, Albert; Maazouz, Yassine; Díez Escudero, Anna; Español Pons, Montserrat; Montufar Jiménez, Edgar Benjamin; Ginebra Molins, Maria Pau (Elsevier, 2018-10-01)
      Article
      Restricted access - publisher's policy
      There is an urgent need of synthetic bone grafts with enhanced osteogenic capacity. This can be achieved by combining biomaterials with exogenous growth factors, which however can have numerous undesired side effects, but ...