Now showing items 1-20 of 31

    • 3D printing of hierarchical porous biomimetic hydroxyapatite scaffolds: Adding concavities to the convex filaments 

      Konka, Joanna Magdalena; Buxadera Palomero, Judit; Español Pons, Montserrat; Ginebra Molins, Maria Pau (Elsevier, 2021-01-01)
      Article
      Open Access
      Covenantee:   Institut de Bioenginyeria de Catalunya
      Porosity plays a key role on the osteogenic performance of bone scaffolds. Direct Ink Writing (DIW) allows the design of customized synthetic bone grafts with patient-specific architecture and controlled macroporosity. ...
    • A multiparametric advection-diffusion reduced-order model for molecular transport in scaffolds for osteoinduction 

      Muixí Ballonga, Alba; Zlotnik, Sergio; Calvet Tordera, Pere; Español Pons, Montserrat; Lodoso Torrecilla, Irene; Ginebra Molins, Maria Pau; Díez, Pedro; García González, Alberto (Springer Nature, 2022-05-05)
      Article
      Open Access
      Scaffolds are microporous biocompatible structures that serve as material support for cells to proliferate, differentiate and form functional tissue. In particular, in the field of bone regeneration, insertion of scaffolds ...
    • a-tricalcium phosphate synthesis from amorphous calcium phosphate: structural characterization and hydraulic reactivity 

      Martínez, Thomas; Español Pons, Montserrat; Charvillat, Cedric; Marsan, Olivier; Ginebra Molins, Maria Pau; Rey, Christian; Sarda, Stephanie (Springer, 2021-05-24)
      Article
      Open Access
      Covenantee:   Université Toulouse III - Paul Sabatier / Institut de Bioenginyeria de Catalunya
      In the present study, amorphous tricalcium phosphate (TCP) has been synthetized by a wet route to obtain low temperature a-TCP at 650 °C (LT-aTCP) and compare its structural, physical–chemical and thermal properties with ...
    • Bioceramics and bone healing 

      Ginebra Molins, Maria Pau; Español Pons, Montserrat; Maazouz, Yassine; Bergez, Victor; Pastorino Carraz, David (2018-05-01)
      Article
      Open Access
      - Calcium phosphates have long been used as synthetic bone grafts. Recent studies have shown that the modulation of composition and textural properties, such as nano-, micro- and macro-porosity, is a powerful strategy to ...
    • Biomimetic versus sintered calcium phosphates: The in vitro behavior of osteoblasts and mesenchymal stem cells 

      Sadowska, Joanna Maria; Guillem Martí, Jordi; Montufar Jiménez, Edgar Benjamin; Español Pons, Montserrat; Ginebra Molins, Maria Pau (2017-12-01)
      Article
      Open Access
      © Copyright 2017, Mary Ann Liebert, Inc.The fabrication of calcium phosphates using biomimetic routes, namely, precipitation processes at body temperature, results in distinct features compared to conventional sintered ...
    • Calcium phosphate cements as drug delivery materials 

      Ginebra Molins, Maria Pau; Canal Barnils, Cristina; Español Pons, Montserrat; Pastorino, David; Montufar Jiménez, Edgar Benjamin (2012-01-25)
      Article
      Restricted access - publisher's policy
      Calcium phosphate cements are used as synthetic bone grafts, with several advantages, such as their osteoconductivity and injectability. Moreover, their low-temperature setting reaction and intrinsic porosity allow for the ...
    • Design strategies for biomimetic bone implants from calcium phosphate cements (Part 1) 

      Canal Barnils, Cristina; Español Pons, Montserrat; Ginebra Molins, Maria Pau (2016)
      Article
      Restricted access - publisher's policy
    • Design strategies for biomimetic bone implants from calcium phosphate cements (Part II) 

      Canal Barnils, Cristina; Español Pons, Montserrat; Ginebra Molins, Maria Pau (2016)
      Article
      Restricted access - publisher's policy
    • Development of bactericidal nanopillar topographies in calcium phosphates 

      Iglesias-Fernández, Marc; Español Pons, Montserrat; Ginebra Molins, Maria Pau (Universitat Politècnica de Catalunya, 2022-06-15)
      Conference lecture
      Open Access
    • EDTA and NTA effectively tune the mineralization of calcium phosphate from bulk aqueous solution 

      Hentrich, Doreen; Tauer, Klaus; Español Pons, Montserrat; Ginebra Molins, Maria Pau; Taubert, Andreas (2017-12-01)
      Article
      Open Access
      Covenantee:   Universität Potsdam / Max-Planck-Institut für Kolloid- und Grenzflächenforschung
      This study describes the effects of nitrilotriacetic acid (NTA) and ethylenediaminotetraacetic acid (EDTA) on the mineralization of calcium phosphate from bulk aqueous solution. Mineralization was performed between pH 6 ...
    • Effect of calcium phosphate heparinization on the in vitro inflammatory response and osteoclastogenesis of human blood precursor cells 

      Díez Escudero, Anna; Torreggiani, E.; Pompo, Gemma di; Español Pons, Montserrat; Persson, Cecilia; Ciapetti, Gabriela; Baldini, Nicola; Ginebra Molins, Maria Pau (2019-01-01)
      Article
      Open Access
      Covenantee:   Istituto Ortopedico Rizzoli / Uppsala universitet / Università di Bologna / Institut de Bioenginyeria de Catalunya
      The immobilization of natural molecules on synthetic bone grafts stands as a strategy to enhance their biological interactions. During the early stages of healing, immune cells and osteoclasts (OC) modulate the inflammatory ...
    • Effect of moisture on the reactivity of alpha-tricalcium phosphate 

      Español Pons, Montserrat; Davis, Emilia; Meslet, Eliott; Mestres, Gemma; Montufar Jiménez, Edgar Benjamin; Ginebra Molins, Maria Pau (2023-01-01)
      Article
      Open Access
      The ability of the high-temperature polymorph of tricalcium phosphate, a-TCP, to hydrolyse to calcium-deficient hydroxyapatite underlies many developments in the field of synthetic bone grafts, including calcium phosphate ...
    • Effects of molecular weight and concentration of poly(acrylic acid) on biomimetic mineralization of collagen 

      Qi, Yipin; Ye, Zhou; Fok, Alex; Holmes, Brian N.; Español Pons, Montserrat; Ginebra Molins, Maria Pau; Aparicio Badenas, Conrado José (American Chemical Society (ACS), 2018-06-29)
      Article
      Restricted access - publisher's policy
      Inspired by nature, poly(acrylic acid) (PAA) and other polyelectrolytes have been used as noncollagenous proteins (NCPs) surrogates for biomimetic intrafibrillar mineralization of collagen fibrils and, thus, to model the ...
    • Focus ion beam/scanning electron microscopy characterization of osteoclastic resorption of calcium phosphate substrates 

      Díez Escudero, Anna; Español Pons, Montserrat; Montufar Jiménez, Edgar Benjamin; Pompo, Gemma di; Ciapetti, Gabriela; Baldini, Nicola; Ginebra Molins, Maria Pau (2017-02-01)
      Article
      Open Access
      Covenantee:   Istituto Ortopedico Rizzoli
      This article presents the application of dual focused ion beam/scanning electron microscopy (FIB-SEM) imaging for preclinical testing of calcium phosphates with osteoclast precursor cells and how this high-resolution imaging ...
    • Formation of calcium phosphate nanostructures under the influence of self-assembling hybrid elastin-like-statherin recombinamers 

      Hamed Misbah, M.; Español Pons, Montserrat; Quintanilla, Luis; Ginebra Molins, Maria Pau; Rodriguez Cabello, Jose Carlos (2016-01-01)
      Article
      Open Access
      Covenantee:   Universidad de Valladolid
      The self-assembling properties of thermally-sensitive amphiphilic elastin-like multiblock recombinamers have been combined with the capacities of calcium phosphate binding of the SN(A)15 epitope inspired by the salivary ...
    • Heparinization of beta tricalcium phosphate: osteo-immunomodulatory effects 

      Díez Escudero, Anna; Español Pons, Montserrat; Bonany Mariñosa, Mar; Persson, Cecilia; Ginebra Molins, Maria Pau (2018-03-07)
      Article
      Open Access
      Immune cells play a vital role in regulating bone dynamics. This has boosted the interest in developing biomaterials that can modulate both the immune and skeletal systems. In this study, calcium phosphates discs (i.e., ...
    • High-aspect-ratio nanostructured hydroxyapatite: towards new functionalities for a classical material 

      Díez Escudero, Anna; Español Pons, Montserrat; Ginebra Molins, Maria Pau (Royal Society of Chemistry (RSC), 2024)
      Article
      Open Access
      Hydroxyapatite-based materials have been widely used in countless applications, such as bone regeneration, catalysis, air and water purification or protein separation. Recently, much interest has been given to controlling ...
    • Hydroxyapatite nanoparticles-cell interaction: New approaches to disclose the fate of membrane-bound and internalised nanoparticles 

      Bonany Mariñosa, Mar; Pérez Berná, Ana Joaquina; Ducic, Tanja; Pereiro López, Eva; Martín Gómez, Helena; Mas Moruno, Carlos; van Rijt, Sabine; Zhao, Zhitong; Español Pons, Montserrat; Ginebra Molins, Maria Pau (Elsevier, 2022-11-01)
      Article
      Open Access
      Covenantee:   Sincrotró ALBA / Universiteit van Maastricht / Institut de Bioenginyeria de Catalunya / Nanyang Technological University
      Hydroxyapatite nanoparticles are popular tools in bone regeneration, but they have also been used for gene delivery and as anticancer drugs. Understanding their mechanism of action, particularly for the latter application, ...
    • Impact of biomimicry in the design of osteoinductive bone substitutes: nanoscale matters 

      Barba Serrahima, Albert; Díez Escudero, Anna; Español Pons, Montserrat; Bonany Mariñosa, Mar; Sadowska, Joanna Maria; Guillem Martí, Jordi; Ohman, Caroline; Persson, Cecilia; Manzanares, Maria Cristina; Franch, Jordi; Ginebra Molins, Maria Pau (2019-01-01)
      Article
      Open Access
      Covenantee:   Universitat Autònoma de Barcelona / Uppsala universitet / Universitat de Barcelona. Departament de Patologia i Terapèutica Experimental / Institut de Bioenginyeria de Catalunya
      Bone apatite consists of carbonated calcium-deficient hydroxyapatite (CDHA) nanocrystals. Biomimetic routes allow fabricating synthetic bone grafts that mimic biological apatite. In this work, we explored the role of two ...
    • Impact of porosity and electrolyte composition on the surface charge of hydroxyapatite biomaterials 

      Español Pons, Montserrat; Ginebra Molins, Maria Pau; Dory, Jean Baptiste (-, 2015-12-18)
      Article
      Open Access
      The success or failure of a material when implanted in the body is greatly determined by the surface properties of the material and the host tissue reactions. The very first event that takes place after implantation is the ...