Now showing items 1-3 of 3

    • Direct force measurements of subcellular mechanics in confinement using optical tweezers 

      Català Castro, Frederic; Venturini, Valeria; Ruprecht, Verena; Krieg, Michael (2021-08-31)
      Article
      Open Access
      During the development of a multicellular organism, a single fertilized cell divides and gives rise to multiple tissues with diverse functions. Tissue morphogenesis goes in hand with molecular and structural changes at the ...
    • Mechanisms and functions of the nucleus as a mechano-controller of cell contractility and migration plasticity 

      Venturini, Valeria (Universitat Politècnica de Catalunya, 2022-04-08)
      Doctoral thesis
      Open Access
      Living tissues are crowded and dynamic environments, in which signalling molecules and physical forces constantly act on single cells. To ensure correct tissue development and homeostasis, cells function like small processors: ...
    • The nucleus measures shape changes for cellular proprioception to control dynamic cell behavior 

      Venturini, Valeria; Pezzano, Fabio; Català Castro, Frederic; Häkkinen, Hanna-Maria; Jiménez-Delgado, Senda; Colomer Rosell, Mariona; Marro, Monica; Tolosa-Ramon, Queralt; Paz-López, Sonia; Valverde, Miguel A.; Weghuber, Julian; Loza- Alvarez, Pablo; Krieg, Michael; Wieser, Stefan; Ruprecht, Verena (ACS, 2020-10-16)
      Article
      Open Access
      Single cells continuously experience and react to mechanical challenges in three-dimensional tissues. Spatial constraints in dense tissues, physical activity, and injury all impose changes in cell shape. How cells can ...