Now showing items 1-12 of 12

    • A truss element for modelling reversible softening in living tissues 

      Muñoz Romero, José; Conte, Vito; Asadipour, Nina; Miodownik, M. (2013-04-01)
      Article
      Open Access
      We resort to non-linear viscoelasticity to develop a truss element able to model reversible softening in lung epithelial tissues undergoing transient stretch. Such a Maxwell truss element is built by resorting to a ...
    • Cell-centered truss model for the analysis of cell rheology and remodelling 

      Muñoz Romero, José; Asadipour, Nina; Albo, Santiago (2013)
      Conference lecture
      Open Access
      Soft active tissues exhibit softening, hardening, and reversible fluidisation [14]. The result of these non-linear behaviour is due to multiple processes taking part at di erent scales: active protein motors that actuate ...
    • Cell-centred model for non-linear tissue rheology and active remodelling 

      Asadipour, Nina; Mosaffa, Payman; Muñoz Romero, José (Centre Internacional de Mètodes Numèrics en Enginyeria (CIMNE), 2014)
      Conference report
      Restricted access - publisher's policy
      Soft active tissues exhibit softening, hardening, and reversible fluidisation. The result of these non-linear behaviour is due to multiple processes taking part at different scales: active protein motors that actuate at ...
    • Cell-centred model for the simulation of curved cellular monolayers 

      Mosaffa, Payman; Asadipour, Nina; Millán, Raúl Daniel; Rodríguez Ferran, Antonio; Muñoz Romero, José (2015)
      Article
      Open Access
      This paper presents a cell-centred model for the simulation of planar and curved multicellular soft tissues. We propose a computational model that includes stress relaxation due to cell reorganisation (intercellular ...
    • Computational tools for multicellular systems 

      Muñoz Primer, Jose J.; Mosaffa, Payman; Asadipour, Nina; Conte, Vito (EUETIB, 2014-12-01)
      Conference report
      Open Access
      Macroscopic deformations in embryonic soft tissues are due to the intra-cellular remodelling and cell intercalation. We here present a computational approach that can handle the two types of deformations, and also take ...
    • Hybrid cell centred/vertex model for cellular nanolayers 

      Mosaffa, Payman; Asadipour, Nina; Millán, Daniel; Rodríguez Ferran, Antonio; Muñoz Romero, José (2015)
      Conference report
      Open Access
      Macroscopic deformations in embryonic soft tissues are due to the intra-cellular remodelling and cell intercalation. We here present a computational approach that can handle the two types of deformations, and also take ...
    • Hybrid cell centred/vertex model for large tissue deformations 

      Muñoz Romero, José; Mosaffa, Payman; Mao, Yanlan; Tetley, Rob; Asadipour, Nina; Rodríguez Ferran, Antonio (2016)
      Conference report
      Open Access
      Macroscopic deformations in embryonic soft tissues are due to the intra-cellular remodelling and cell intercalation. We here present a computational approach that can handle the two types of deformations, and also take ...
    • Modelling of non-linear viscoelastic tissues with bar elements 

      Asadipour, Nina (Universitat Politècnica de Catalunya, 2012-03)
      Master thesis
      Open Access
      In this work we develop a viscoelastic bar element that can handle multiple rheological laws with non-linear elastic and non-linear viscous material models. The bar element is built by joining in series an elastic and ...
    • Numerical modelling of multicellular dynamics 

      Muñoz Romero, José; Asadipour, Nina; Mosaffa, P; Conte, V (EUETIB, 2013-12)
      Conference lecture
      Open Access
      En este trabajo se desarrollar un modelo computacional que permite simular y predecir las deformaciones sucesivas que tienen lugar durante fases de la embriogénesis que han sido biológicamente bien detalladas. Las simulaciones ...
    • Porous-based rheological model for tissue fluidisation 

      Asadipour, Nina; Trepat, Xavier; Muñoz Romero, José (2016-11-01)
      Article
      Open Access
      It has been experimentally observed that cells exhibit a fluidisation process when subjected to a transient stretch, with an eventual recovery of the mechanical properties upon removal of the applied deformation. This ...
    • Rheological models for tissue relaxation and fluidisation 

      Asadipour, Nina (Universitat Politècnica de Catalunya, 2016-03-04)
      Doctoral thesis
      Open Access
      We present a cell-centred model for the simulation of multicellular soft tissues that takes into account the underlying active process at the cytoskeletal level, and allows for active and passive cell-cell reorganisation ...
    • Stress relaxation in epithelial monolayers is controlled by the actomyosin cortex 

      Khalilgharibi, Nargess; Fouchard, Jonathan; Asadipour, Nina; Barrientos, Ricardo; Duda, Maria; Bonfanti, Alessandra; Yonis, Amina; Harris, Andrew; Mosaffa, Payman; Fujita, Yasuyuki; Kabla, Alexandre; Mao, Yanlan; Baum, Buzz; Muñoz Romero, José; Miodownik, Mark; Charras, Guillaume (2019-01-01)
      Article
      Open Access
      Epithelial monolayers are one-cell thick tissue sheets that separate internal and external environments. As part of their function, they have to withstand extrinsic mechanical stresses applied at high strain rates. However, ...