Browsing by Author "Rubí Sans, Gerard"Més informacióMés informació

Now showing items 1-7 of 7

    • Bioprinting decellularized breast tissue for the development of three-dimensional breast cancer models 

      Blanco Fernández, Bárbara; Rey Viñoles, Sergi; Bagci, Gülsün; Rubí Sans, Gerard; Otero, Jorge; Navajas Navarro, Daniel; Pérez Amodio, Soledad Graciela; Engel López, Elisabeth (2022-06-23)
      Article
      Open Access
      The tumor extracellular matrix (ECM) plays a vital role in tumor progression and drug resistance. Previous studies have shown that breast tissue-derived matrices could be an important biomaterial to recreate the complexity ...

    • Development and angiogenic potential of cell-derived microtissues using microcarrier-template 

      Rubí Sans, Gerard; Cano Garcia, Irene; Pérez Amodio, Soledad Graciela; Blanco, Bárbara; Mateos Timoneda, Miguel Ángel; Engel López, Elisabeth (2021-02-25)
      Article
      Open Access
      Tissue engineering and regenerative medicine approaches use biomaterials in combination with cells to regenerate lost functions of tissues and organs to prevent organ transplantation. However, most of the current strategies ...

    • Development of a three-dimensional bioengineered platform for articular cartilage regeneration 

      Rubí Sans, Gerard; Recha Sancho, Lourdes; Pérez Amodio, Soledad Graciela; Mateos Timoneda, Miguel Ángel; Semino Margrett, Carlos Eduardo; Engel López, Elisabeth (2020-01-01)
      Article
      Open Access
      Degenerative cartilage pathologies are nowadays a major problem for the world population. Factors such as age, genetics or obesity can predispose people to suffer from articular cartilage degeneration, which involves severe ...

    • Development of an in vitro three-dimensional colorectal cancer model using cell-derived extracellular matrices 

      Rubí Sans, Gerard (2022-06-10)
      Doctoral thesis
      Open Access
      (English) Oncogenic pathologies are the second leading cause of death worldwide only after cardiovascular diseases. It is estimated that, by 2030, the number of patients diagnosed with this disease will increase by nearly ...

    • Engineered microtissues for the bystander therapy against cancer 

      Blanco Fernández, Bárbara; Cano Torres, Irene; Garrido, Cristina; Rubí Sans, Gerard; Sanchez Cid, Lourdes; Guerra Rebollo, Marta; Rubio, Nuria; Blanco, Jeronimo; Pérez Amodio, Soledad Graciela; Mateos Timoneda, Miguel Ángel; Engel López, Elisabeth (Elsevier, 2021-02-01)
      Article
      Open Access
      Thymidine kinase expressing human adipose mesenchymal stem cells (TK-hAMSCs) in combination with ganciclovir (GCV) are an effective platform for antitumor bystander therapy in mice models. However, this strategy requires ...

    • Engineering cell-derived matrices: from 3D models to advanced personalized therapies 

      Rubí Sans, Gerard; Castaño Linares, Óscar; Cano Torres, Irene; Mateos Timoneda, Miguel Ángel; Pérez Amodio, Soledad Graciela; Engel López, Elisabeth (2020-07-02)
      Article
      Open Access
      Regenerative medicine and disease models have evolved in recent years from two to three dimensions, providing in vitro constructs that are more similar to in vivo tissues. By mimicking native tissues, cell-derived matrices ...

    • Hidrogels biomimètics per a enginyeria de teixits 

      Rubí Sans, Gerard (Universitat Politècnica de Catalunya, 2014-07-09)
      Bachelor thesis
      Restricted access - author's decision
      Covenantee:   Institut de Bioenginyeria de Catalunya
      This final grade project, developed in the biomaterials for regenerative therapies group of research in the Institute for bioengineering of Catalonia (IBEC), was encompassed within a major project consisting in developing, ...