Now showing items 1-20 of 37

    • 3D printing with star-shaped strands: a new approach to enhance in vivo bone regeneration 

      Raymond Llorens, Santiago; Lehmann, Cyril; Thorel, Emilie; Benítez Iglesias, Raúl; Riveiro Rodríguez, Antonio; Pou Saracho, Juan María; Manzanares Céspedes, Maria Cristina; Franch Serracanta, Jordi; Canal Barnils, Cristina; Ginebra Molins, Maria Pau (Elsevier, 2022-06-01)
      Article
      Open Access
      Covenantee:   Mimetis Biomaterials / Institut de Recerca Sant Joan de Déu / Universidade de Vigo / Universitat de Barcelona / Universitat Autònoma de Barcelona / Institut de Bioenginyeria de Catalunya
      Concave surfaces have shown to promote bone regeneration in vivo. However, bone scaffolds obtained by direct ink writing, one of the most promising approaches for the fabrication of personalized bone grafts, consist mostly ...
    • Ageing is associated with deterioration of calcium homeostasis in isolated human right atrial myocytes 

      Herrainz, Adela; Álvarez-García, Jesus; Llach, A; Molina, Cristina E.; Fernandes, Jacqueline; Ferrero-Gregori, Andreu; Rodríguez, Cristina; Vallmitjana Lees, Alexander; Benítez Iglesias, Raúl; Padró, Josep M.; Martínez-González, José; Cinca Cosculluela, Juan; Hove-Madsen, Leif (2015-02-24)
      Article
      Open Access
      Ageing-related cardiac disorders such as heart failure and atrial fibrillation often present with intracellular calcium homeostasis dysfunction. However, knowledge of the intrinsic effects of ageing on cellular calcium ...
    • Ca2+-CaM dependent inactivation of RyR2 underlies Ca2+ alternans in intact heart 

      Guo, Wenting; Benítez Iglesias, Raúl; Hove-Madsen, Leif; Álvarez Lacalle, Enrique; Echebarría Domínguez, Blas (2021-02-19)
      Article
      Open Access
      Rationale: Ca2+ alternans plays an essential role in cardiac alternans that can lead to ventricular fibrillation, but the mechanism underlying Ca2+ alternans remains undefined. Increasing evidence suggests that Ca2+ ...
    • Cardiac electrical defects in progeroid mice and Hutchinson-Gilford progeria syndrome patients with nuclear lamina alterations 

      Riveras Torres, Jose; Calvo, Conrado J.; Llach, Anna; Gúzman Martínez, Gabriela; Caballero, Ricardo; González Gómez, Cristina; Jiménez Borreguero, Luís J.; Guadix, Juan A.; Osorio, Fernando G.; López Otín, Carlos; Herraiz Martínez, Adela; Cabello, Nuria; Vallmitjana Lees, Alexander; Benítez Iglesias, Raúl; Gordon, Leslie B. (2016-11-15)
      Article
      Open Access
      Hutchinson–Gilford progeria syndrome (HGPS) is a rare genetic disease caused by defective prelamin A processing, leading to nuclear lamina alterations, severe cardiovascular pathology, and premature death. Prelamin A ...
    • Cardiac ryanodine receptor calcium release deficiency syndrome 

      Guo, Wenting; Benítez Iglesias, Raúl; Hove-Madsen, Leif (2021-02-03)
      Article
      Open Access
      Cardiac ryanodine receptor (RyR2) gain-of-function mutations cause catecholaminergic polymorphic ventricular tachycardia, a condition characterized by prominent ventricular ectopy in response to catecholamine stress, which ...
    • Data-based fault detection in chemical processes: Managing records with operator intervention and uncertain labels 

      Askarian, Mahdieh; Benítez Iglesias, Raúl; Graells Sobré, Moisès; Zarghami, Reza (2016-06-23)
      Article
      Open Access
      Developing data-driven fault detection systems for chemical plants requires managing uncertain data labels and dynamic attributes due to operator-process interactions. Mislabeled data is a known problem in computer science ...
    • Detection of calcium release from individual RyR2 clusters in cardiomyocites 

      Nolla Colomer, Carme; Vallmitjana Lees, Alexander; Hove-Madsen, Leif; Benítez Iglesias, Raúl (2020-02)
      Article
      Restricted access - publisher's policy
      Cardiac ryanodine receptors (RyR2s) are Ca2þ release channels clustering in the sarcoplasmic reticulum membrane. These clusters are believed to be the elementary units of Ca2þ release. The distribution of these Ca2þ release ...
    • Detection, properties, and frequency of local calcium release from the sarcoplasmic reticulum in teleost cardiomyocytes 

      Llach, Anna; Molina, Cristina E.; Álvarez Lacalle, Enrique; Tort, Lluis; Benítez Iglesias, Raúl; Hove-Madsen, Leif (2011-08-29)
      Article
      Open Access
      Calcium release from the sarcoplasmic reticulum (SR) plays a central role in the regulation of cardiac contraction and rhythm in mammals and humans but its role is controversial in teleosts. Since the zebrafish is an ...
    • Distribution and function of cardiac ryanodine receptor clusters in live ventricular myocytes 

      Hiess, Florian; Vallmitjana Lees, Alexander; Wang, Ruiwu; Cheng, Hongqiang; ter Keurs, Henk; Chen, Ju; Hove Madsen, Leif; Benítez Iglesias, Raúl; Chen, S. R. Wayne (2015-08-14)
      Article
      Open Access
      The cardiac Ca2+ release channel (ryanodine receptor, RyR2) plays an essential role in excitation-contraction coupling in cardiac muscle cells. Effective and stable excitation-contraction coupling critically depends not ...
    • Dynamic and irregular distribution of RyR2 clusters in the periphery of live ventricular myocytes 

      Hiess, Florian; Detampel, Pascal; Nolla Colomer, Carme; Vallmitjana Lees, Alexander; Ganguly, Anutosh; Amrein, Matthias; ter Keurs, Henk E.D.J; Benítez Iglesias, Raúl; Hove-Madsen, Leif; Chen, S. R. Wayne (2018-01-23)
      Article
      Open Access
      Cardiac ryanodine receptors (RyR2s) are Ca2+ release channels clustering in the sarcoplasmic reticulum membrane. These clusters are believed to be the elementary units of Ca2+ release. The distribution of these Ca2+ release ...
    • EEBE International Day. Com sol·licitar una plaça d'estudis de mobilitat? 

      Benítez Iglesias, Raúl (2021-12-15)
      Audiovisual
      Open Access
    • EEBE International Day. Round Table by students 

      Benítez Iglesias, Raúl (2021-12-15)
      Audiovisual
      Open Access
    • Enhanced plant fault diagnosis based on the characterization of transient stages 

      Monroy, Isaac; Benítez Iglesias, Raúl; Escudero Bakx, Gerard; Graells Sobré, Moisès (Pergamon Press, 2011-12-05)
      Article
      Restricted access - publisher's policy
      This paper introduces a data-based fault diagnosis system that includes an enhanced characterization of faults during transient stages. First, data under abnormal operating conditions (AOC) is projected onto a reference ...
    • How to merge observational and physiological data? A case study of motor skills patterns and heart rate in exercise programs for adult women 

      Castañer Balcells, Marta; Puigarnau, Sílvia; Benítez Iglesias, Raúl; Zurloni, Valentino; Camerino, Oleguer (2017-10-01)
      Article
      Open Access
      The present study analyzes individual and group heart rate responses in exercising adult women. The specific aim was to compare responses during routine workout sessions within a community exercise program with responses ...
    • Human-robot cooperative movement training: learning a novel sensory motor transformation during walking with robotic assistance-as-needed 

      Emken, Jeremy L.; Benítez Iglesias, Raúl; Reinkensmeyer, David J. (BioMed Central Ltd., 2007-03-31)
      Article
      Open Access
      Background A prevailing paradigm of physical rehabilitation following neurologic injury is to "assist-as-needed" in completing desired movements. Several research groups are attempting to automate this principle with ...
    • Hydrothermal processing of 3D-printed calcium phosphate scaffolds enhances bone formation in vivo: a comparison with biomimetic treatment 

      Raymond Llorens, Santiago; Bonany Mariñosa, Mar; Lehmann, Cyril; Thorel, Emilie; Benítez Iglesias, Raúl; Franch Serracanta, Jordi; Canal Barnils, Cristina; Ginebra Molins, Maria Pau (Elsevier, 2021-11-01)
      Article
      Open Access
      Covenantee:   Mimetis Biomaterials / Institut de Recerca Sant Joan de Déu / Universitat Autònoma de Barcelona / Universitat de Barcelona. Departament de Genètica, Microbiologia i Estadística / Institut de Bioenginyeria de Catalunya
      Hydrothermal (H) processes accelerate the hydrolysis reaction of a-tricalcium phosphate (a-TCP) compared to the long-established biomimetic (B) treatments. They are of special interest for patient-specific 3D-printed bone ...
    • Identification of intracellular calcium dynamics in stimulated cardiomyocytes 

      Vallmitjana Lees, Alexander; Barriga, Montserrat; Nenadic, Zoran; Llach, Anna; Álvarez Lacalle, Enrique; Hove-Madsen, Leif; Benítez Iglesias, Raúl (IEEE Press. Institute of Electrical and Electronics Engineers, 2010)
      Conference report
      Open Access
      We have developed an automatic method for the analysis and identification of dynamical regimes in intracellular calcium patterns from confocal calcium images. The method allows the identification of different dynamical ...
    • Identifying basketball plays from sensor data; towards a low-cost automatic extraction of advanced statistics 

      Arbués Sangüesa, Adrià; Moeslund, Thomas B.; Bahnsen, Chris H.; Benítez Iglesias, Raúl (Institute of Electrical and Electronics Engineers (IEEE), 2017)
      Conference report
      Restricted access - publisher's policy
      Advanced statistics have proved to be a crucial tool for basketball coaches in order to improve training skills. Indeed, the performance of the team can be further optimized by studying the behaviour of players under certain ...
    • Influence of sex on intracellular calcium homoeostasis in patients with atrial fibrillation 

      Herraiz Martínez, Adela; Tarifa Lora, Carmen; Jiménez Sábado, Verónica; Llach Martínez, Ana; Colino-Lage, Hildegard; Nolla Colomer, Carme; Benítez Iglesias, Raúl; Ciruela, Francisco; Cinca Cuscullola, Juan Maria; Hove-Madsen, Leif (2021-03-31)
      Article
      Open Access
      Aims Atrial fibrillation (AF) has been associated with intracellular calcium disturbances in human atrial myocytes, but little is known about the potential influence of sex and we here aimed to address this issue. Methods ...
    • Low density lipoproteins promote unstable calcium handling accompanied by reduced SERCA2 and connexin-40 expression in cardiomyocytes 

      Barriga, Montserrat; Cal, Roi; Cabello, Nuria; Llach, Anna; Vallmitjana Lees, Alexander; Benítez Iglesias, Raúl; Badimón, Lina; Cinca, J.; Llorente-Cortés, Vicenta; Hove-Madsen, Leif (2013-03-13)
      Article
      Open Access
      The damaging effects of high plasma levels of cholesterol in the cardiovascular system are widely known, but little attention has been paid to direct effects on cardiomyocyte function. We therefore aimed at testing the ...