Now showing items 1-20 of 84

    • A bayesian test for Hardy-Weinberg equilibrium of bi-allelic X-chromosomal markers 

      Puig Oriol, Xavier; Ginebra Molins, Josep; Graffelman, Jan (2017-07)
      Article
      Open Access
      The X chromosome is a relatively large chromosome, harboring a lot of genetic information. Much of the statistical analysis of X-chromosomal information is complicated by the fact that males only have one copy. Recently, ...
    • A Compositional Approach to Allele Sharing Analysis 

      Galván Femenía, Iván; Graffelman, Jan (Springer, 2016)
      Part of book or chapter of book
      Restricted access - publisher's policy
      Relatedness is of great interest in population-based genetic association studies. These studies search for genetic factors related to disease. Many statistical methods used in population-based genetic association studies ...
    • A genome-wide study of Hardy–Weinberg equilibrium with next generation sequence data 

      Graffelman, Jan; Jain, Deepti; Weir, B.S. (2017-04-03)
      Article
      Open Access
      Statistical tests for Hardy–Weinberg equilibrium have been an important tool for detecting genotyping errors in the past, and remain important in the quality control of next generation sequence data. In this paper, we ...
    • A likelihood ratio approach for identifying three-quarter siblings in genetic databases 

      Galván Femenía, Iván; Barceló Vidal, Carles; Sumoy, Lauro; Moreno Aguado, Victor Raul; de Cid, Rafael; Graffelman, Jan (2021-01-15)
      Article
      Open Access
      The detection of family relationships in genetic databases is of interest in various scientific disciplines such as genetic epidemiology, population and conservation genetics, forensic science, and genealogical research. ...
    • A log-ratio biplot approach for exploring genetic relatedness based on identity by state 

      Graffelman, Jan; Galván Femenía, Iván; de Cid, Rafael; Barceló Vidal, Carles (2019-04-24)
      Article
      Open Access
      The detection of cryptic relatedness in large population-based cohorts is of great importance in genome research. The usual approach for detecting closely related individuals is to plot allele sharing statistics, based on ...
    • A network algorithm for the X chromosomal exact test for Hardy–Weinberg equilibrium with multiple alleles 

      Graffelman, Jan; Ortoleva, Leonardo (2021-03-23)
      Article
      Open Access
      Statistical methodology for testing the Hardy-Weinberg equilibrium at X chromosomal variants has recently experienced considerable development. Up to a few years ago, testing X chromosomal variants for equilibrium was ...
    • An application of the isometric log-ratio transformation in relatedness research 

      Graffelman, Jan; Galván Femenía, Iván (Springer, 2016)
      Part of book or chapter of book
      Restricted access - publisher's policy
      Abstract Genetic marker data contains information on the degree of relatedness of a pair of individuals. Relatedness investigations are usually based on the extent to which alleles of a pair of individuals match over a set ...
    • ANÀLISI MULTIVARIANT 

      Graffelman, Jan (Universitat Politècnica de Catalunya, 2013-01-09)
      Exam
      Restricted access to the UPC academic community
    • Assessment of kinship detection using RNA-seq data 

      Blay Magriñá, Natàlia; Casas, Eduard; Galván Femenía, Iván; Graffelman, Jan; de Cid, Rafael; Vavouri, Tanya (2019-12-02)
      Article
      Open Access
      Analysis of RNA sequencing (RNA-seq) data from related individuals is widely used in clinical and molecular genetics studies. Prediction of kinship from RNA-seq data would be useful for confirming the expected relationships ...
    • Bayesian model selection for the study of Hardy-Weinberg proportions and homogeneity of gender allele frequencies 

      Puig Oriol, Xavier; Ginebra Molins, Josep; Graffelman, Jan (2019-05-29)
      Article
      Restricted access - publisher's policy
      Standard statistical tests for Hardy-Weinberg equilibrium assume the equality of allele frequencies in the sexes, whereas tests for the equality of allele frequencies in the sexes assume Hardy–Weinberg equilibrium. This ...
    • Contributions to the multivariate Analysis of Marine Environmental Monitoring 

      Graffelman, Jan (Universitat Politècnica de Catalunya, 2000-09-12)
      Doctoral thesis
      Open Access
      The thesis parts from the view that statistics starts with data, and starts by introducing the data sets studied: marine benthic species counts and chemical measurements made at a set of sites in the Norwegian Ekofisk oil ...
    • Correlation between tobacco control policies, consumption of rolled tobacco and e-cigarettes, and intention to quit conventional tobacco, in Europe 

      Lidón-Moyano, Cristina; Martín Sánchez, Juan Carlos; Saliba, Patrick; Graffelman, Jan; Martínez Sánchez, Jose Maria (2016-02-17)
      Article
      Open Access
    • ESTADISTICA 

      Graffelman, Jan (Universitat Politècnica de Catalunya, 2014-06-04)
      Exam
      Restricted access to the UPC academic community
    • ESTADÍSTICA 

      Graffelman, Jan (Universitat Politècnica de Catalunya, 2013-06-27)
      Exam
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    • ESTADÍSTICA 

      Graffelman, Jan (Universitat Politècnica de Catalunya, 2012-05-31)
      Exam
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    • ESTADÍSTICA 

      Graffelman, Jan (Universitat Politècnica de Catalunya, 2013-07-04)
      Exam
      Restricted access to the UPC academic community
    • ESTADÍSTICA 

      Graffelman, Jan (Universitat Politècnica de Catalunya, 2013-04-05)
      Exam
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    • ESTADÍSTICA 

      Graffelman, Jan (Universitat Politècnica de Catalunya, 2012-03-20)
      Exam
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    • ESTADÍSTICA 

      Graffelman, Jan (Universitat Politècnica de Catalunya, 2015-06-04)
      Exam
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    • ESTADÍSTICA MATEMÀTICA 2 ( convocatòria extraordinaria) 

      Graffelman, Jan (Universitat Politècnica de Catalunya, 2010-07-02)
      Exam
      Restricted access to the UPC academic community