Now showing items 1-10 of 10

    • Cold atmospheric plasma enhances doxorubicin selectivity in metastasic bone cancer 

      Mateu Sanz, Miguel; Ginebra Molins, Maria Pau; Tornin Cavielles, Juan; Canal Barnils, Cristina (2022-08)
      Article
      Open Access
      High-dose systemic chemotherapy constitutes a main strategy in the management of bone metastases, employing drugs like doxorubicin (DOX), related with severe side effects. To solve this issue, Cold Atmospheric Plasmas (CAP) ...
    • Cold atmospheric plasma: a new strategy based primarily on oxidative stress for osteosarcoma therapy 

      Mateu Sanz, Miguel; Tornin Cavielles, Juan; Ginebra Molins, Maria Pau; Canal Barnils, Cristina (Multidisciplinary Digital Publishing Institute (MDPI), 2021-02-23)
      Article
      Open Access
      Osteosarcoma is the most common primary bone tumor, and its first line of treatment presents a high failure rate. The 5-year survival for children and teenagers with osteosarcoma is 70% (if diagnosed before it has metastasized) ...
    • Cold plasma and inhibition of STAT3 selectively target tumorigenicity in osteosarcoma 

      Tornin Cavielles, Juan; Mateu Sanz, Miguel; Rey, Veronica; Murillo, Dzohara; Huergo García, Carmen; Gallego, Borja; Rodríguez, Aida; Rodríguez, René; Canal Barnils, Cristina (2023-06-01)
      Article
      Open Access
      Covenantee:   Institut de Recerca Sant Joan de Déu / Hospital Universitario Central de Asturias / Instituto Universitario de Oncología del Principado de Asturias / CIBERONC. Centro de Investigación Biomédica en Red. Cáncer
      Osteosarcoma (OS) is a malignant type of bone cancer that arises in periods of increased bone formation. Curative strategies for these types of tumors have remained essentially unchanged for decades and the overall survival ...
    • Cold plasma-treated ringer’s saline: a weapon to target osteosarcoma 

      Mateu Sanz, Miguel; Tornín, Juan; Brulin, Bénédicte; Khlyustova, Anna; Ginebra Molins, Maria Pau; Layrolle, Pierre; Canal Barnils, Cristina (2020-01-17)
      Article
      Open Access
      Covenantee:   Institut de Bioenginyeria de Catalunya / Université de Nantes
      Osteosarcoma (OS) is the main primary bone cancer, presenting poor prognosis and difficult treatment. An innovative therapy may be found in cold plasmas, which show anti-cancer effects related to the generation of reactive ...
    • In vitro generation of novel functionalized biomaterials for use in oral and dental regenerative medicine applications. Running title: Fibrin-agarose functionalized scaffolds 

      Blanco Elices, Cristina; España Guerrero, Enrique; Mateu Sanz, Miguel; Sánchez Porras, David; García García, Oscar Darío; Sanchéz Quevedo, Maria del Carmen; Fernández Valadés, Ricardo; Alaminos Mingorance, Miguel; Martín Piedra, Miguel Angel; Garzón Bello, Ingrid Johanna (Multidisciplinary Digital Publishing Institute (MDPI), 2020-04-01)
      Article
      Open Access
      Covenantee:   Universidad de Granada
      Recent advances in tissue engineering offer innovative clinical alternatives in dentistry and regenerative medicine. Tissue engineering combines human cells with compatible biomaterials to induce tissue regeneration. ...
    • Oxidation of lactate to pyruvate mediates the cytotoxic potential of physical plasma-treated saline solutions in ovarian cancer 

      Bucci, Cristina; Tampieri, Francesco; Mateu Sanz, Miguel; Laurita, Romolo; Colombo, Vittorio; Canal Barnils, Cristina (John Wiley & sons, 2023-10-02)
      Article
      Open Access
      Covenantee:   Università di Bologna / Institut de Recerca Sant Joan de Déu
      Epithelial ovarian cancer (EOC) is the most common type of gynecological tumor, presenting poor prognosis at diagnosis and with recurrences being frequently observed. Reactive species generated by physical plasma and ...
    • Plasma-conditioned liquids in bone cancer therapy 

      Tampieri, Francesco; Labay, Cédric Pierre; Espona Noguera, Albert; Solé Martí, Xavier; Mateu Sanz, Miguel; Tornín, Juan; Canal Barnils, Cristina (2022)
      Conference report
      Open Access
    • Pyruvate plays a main role in the antitumoral selectivity of cold atmospheric plasma in osteosarcoma 

      Tornin Cavielles, Juan; Mateu Sanz, Miguel; Rodríguez, Aida; Labay, Cédric Pierre; Rodríguez, Rene; Canal Barnils, Cristina (Nature, 2019-07-23)
      Article
      Open Access
      Covenantee:   Hospital Universitario Central de Asturias / Instituto Universitario de Oncología del Principado de Asturias / Centro de Investigación Biomédica en Red. Bioingeniería, Biomateriales y Nanomedicina
      Osteosarcoma (os) is the most common primary bone tumor but current therapies still have poor prognosis. Cold Atmospheric Plasma (CAP) and Plasma activated media (PAM) have shown potential to eliminate cancer cells in other ...
    • Redefining biomaterial biocompatibility: challenges for artificial intelligence and text mining 

      Mateu Sanz, Miguel; Fuenteslópez, Carla V.; Uribe Gomez, Juan; Haugen, Håvard Jostein; Pandit, Abhay; Ginebra Molins, Maria Pau; Hakimi, Osnat; Krallinger, Martin; Samara, Athina (Elsevier, 2023-10-17)
      Article
      Open Access
      Covenantee:   University of Oxford / NUIG National University of Ireland Galway / Universitetet i Oslo / aMoon Ventures / Barcelona Supercomputing Center
      The surge in ‘Big data’ has significantly influenced biomaterials research and development, with vast data volumes emerging from clinical trials, scientific literature, electronic health records, and other sources. ...
    • Selectively targeting tumorigenicity in osteosarcoma 

      Tornin Cavielles, Juan; Mateu Sanz, Miguel; Rey, Verónica; Murillo, Dzohara; Huergo, Carmen; Rodríguez, Aida; Rodríguez, René; Canal Barnils, Cristina (Universitat Politècnica de Catalunya, 2022-03-14)
      Dataset
      Open Access