• A novel hybrid nanofibrous strategy to target progenitor cells for cost-effective in situ angiogenesis 

      Sachot, Nadège; Castaño Linares, Óscar; Oliveira, Hugo; Martí Muñoz, Joan; Roguska, Agata; Amedee, Joelle; Lewandowska, Malgorzata; Planell Estany, Josep Anton; Engel López, Elisabeth (Royal Society of Chemistry, 2016-11-02)
      Article
      Accés obert
      Although the impact of composites based on Ti-doped calcium phosphate glasses is low compared with that of bioglass, they have been already shown to possess great potential for bone tissue engineering. Composites made of ...
    • A novel hybrid nanofibrous strategy to target progenitor cells for cost-effective: In situ angiogenesis 

      Sachot, Nadege; Castaño Linares, Óscar; Oliveira, Hugo; Martí Muñoz, Joan; Roguska, Agata; Amedee, Joelle; Lewandowska, Malgorzata; Planell Estany, Josep Anton; Engel López, Elisabeth (Royal Society of Chemistry, 2016-09-22)
      Article
      Accés obert
      Although the impact of composites based on Ti-doped calcium phosphate glasses is low compared with that of bioglass, they have been already shown to possess great potential for bone tissue engineering. Composites made of ...
    • Chemical design and validation of Ca 2+ -releasing platforms to promote vascularization in tissue regeneration 

      Martí Muñoz, Joan (2018-11-14)
      Tesi
      Accés obert
      An insufficient vascularization of the wound site is often the cause of failure in tissue regeneration. The use of cell therapy or growth factors has introduced promising results, nevertheless, they are risky, expensive ...
    • Feasible and pure P2O5-CaO nanoglasses: An in-depth NMR study of synthesis for the modulation of the bioactive ion release 

      Martí Muñoz, Joan; Xuriguera Martin, Elena; Layton, John W.; Planell Estany, Josep Anton; Rankin, Stephen E.; Engel López, Elisabeth; Castaño Linares, Óscar (Elsevier, 2019-01-01)
      Article
      Accés obert
      The use of bioactive glasses (e.g. silicates, phosphates, borates) has demonstrated to be an effective therapy for the restoration of bone fractures, wound healing and vascularization. Their partial dissolution towards the ...
    • In vitro evaluation of degradable electrospun polylactic acid/bioactive calcium phosphate ormoglass scaffolds 

      Majchrowicz, Anna; Roguska, Agata; Krawczynska, A.; Lewandowska, Malgorzata; Martí Muñoz, Joan; Engel López, Elisabeth; Castaño Linares, Óscar (2020-04-24)
      Article
      Accés obert
      Nowadays, the main limitation for clinical application of scaffolds is considered to be an insufficient vascularization of the implanted platforms and healing tissues. In our studies, we proposed a novel PLA-based hybrid ...
    • Polymeric composite dressings containing calcium-releasing nanoparticles accelerate wound healing in diabetic mice 

      Pérez Amodio, Soledad Graciela; Rubio, Nuria; Vila, Olaia; Navarro Requena, Claudia; Castaño, Óscar; Sanchez Ferrero, Aitor; Martí Muñoz, Joan; Alsina Gibert, Merce; Blanco Fernández, Jerónimo; Engel López, Elisabeth (2020-08-07)
      Article
      Accés obert
      Objective: Wound healing is a complex process that involves the interaction between different cell types and bioactive factors. Impaired wound healing is characterized by a loss in synchronization of these interactions, ...
    • The proangiogenic potential of a novel calcium releasing biomaterial: Impact on cell recruitment 

      Oliveira, Hugo; Catros, Sylvain; Boiziau, Claudine; Siadous, Robin; Martí Muñoz, Joan; Bareille, Reine; Rey, Sylvie; Castaño Linares, Óscar; Planell Estany, Josep Anton; Amedee, Joelle; Engel López, Elisabeth (2016-01-01)
      Article
      Accés obert
      In current bone tissue engineering strategies the achievement of sufficient angiogenesis during tissue regeneration is still a major limitation in order to attain full functionality. Several strategies have been described ...
    • The proangiogenic potential of a novel calcium releasing composite biomaterial: Orthotopic in vivo evaluation 

      Oliveira, Hugo; Catros, Sylvain; Castaño Linares, Óscar; Rey, Sylvie; Siadous, Robin; Clift, Douglas; Martí Muñoz, Joan; Batista, Marc; Bareille, Reine; Planell Estany, Josep Anton; Engel López, Elisabeth; Amedee, Joelle (2017-05-01)
      Article
      Accés obert
      Insufficient angiogenesis remains a major hurdle in current bone tissue engineering strategies. An extensive body of work has focused on the use of angiogenic factors or endothelial progenitor cells. However, these approaches ...