Browsing by Author "Dong, Xiaoyun"
Docosahexaenoic acid phospholipid differentially modulates the conformation of G90V and N55K rhodopsin mutants associated with retinitis pigmentosa Dong, Xiaoyun; Herrera Hernandez, Maria Guadalupe; Ramon Portés, Eva; Garriga Solé, Pere (2017-05-01)
Open AccessRhodopsin is the visual photoreceptor of the retinal rod cells that mediates dim light vision and a prototypical member of the G protein-coupled receptor superfamily. The structural stability and functional performance of ...
Phospholipid bicelles improve the conformational stability of rhodopsin mutants associated with retinitis pigmentosa Dong, Xiaoyun; Ramon Portés, Eva; Herrera Hernandez, Maria Guadalupe; Garriga Solé, Pere (2015-08-11)
Open AccessMutations in the visual photoreceptor rhodopsin are the cause of the retinal degenerative disease retinitis pigmentosa. Some naturally occurring mutations can lead to protein conformational instability. Two such mutations, ...
Dong, Xiaoyun (Universitat Politècnica de Catalunya, 2016-05-25)
Open AccessG-protein coupled receptors (GPCRs) are the largest membrane protein superfamily encoded by the human genome and represent the largest class of drug targets for a wide range of pathological conditions. Two GPCRs members, ...