Browsing by Author "Pérez Álvarez, Nuria"
Now showing items 1-18 of 18
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A randomized pilot trial to evaluate the benefit of the concomitant use of atorvastatin and Raltegravir on immunological markers in protease-inhibitor-treated subjects living with HIV
(Public Library of Science (PLOS), 2020-09-17)
Article
Open AccessObjective Optimization of antiretroviral therapy and anti-inflammatory treatments, such as statins, are among the strategies aimed at reducing metabolic disorders, inflammation and immune activation in people living ... -
Economic evaluation in health research: cohort simultation and applications
(Universitat Politècnica de Catalunya, 2014-07-23)
Doctoral thesis
Open AccessCurrently, resources that may be spent in health care are limited so it is necessary to rationalize their consumption and prioritise their allocation to the options with higher health outcome and economic sustainability. ... -
Effects of integrase inhibitor-based antiretroviral therapy on brain outcomes according to time since acquisition of HIV-1 infection
(Nature, 2021-12-01)
Article
Open AccessIntegrase strand transfer inhibitors (INSTI) are a main component of the current antiretroviral regimens recommended for treatment of HIV infection. However, little is known about the impact of INSTI on neurocognition and ... -
Estudio de los factores asociados a la pérdida de densidad mineral ósea en pacientes infectados con VIH
(2009)
Conference report
Open Access -
High risk and probability of progression to osteoporosis at 10 years in HIV-infected individuals: the role of PIs
(2018-09-01)
Article
Open Access -
Impact of protease inhibitors on the evolution of urinary markers: subanalyses from an observational cross-sectional study
(2016-08)
Article
Open AccessKidney injury (defined as the presence of albuminuria, proteinuria, glycosuria [without hyperglycemia], hematuria, and/or renal hypophosphatemia) is an emerging problem in human immunodeficiency virus (HIV)-infected patients, ... -
In vivo effects of romidepsin on T-cell activation, apoptosis and function in the BCN02 HIV-1 kick&kill clinical trial
(2020-03-20)
Article
Open AccessRomidepsin (RMD) is a well-characterized histone deacetylase inhibitor approved for the treatment of cutaneous T-cell lymphoma. in vitro and in vivo studies have demonstrated that it is able to induce HIV-1 gene expression ... -
In vivo, non-invasive characterization of human bone by hybrid broadband (600-1200 nm) diffuse optical and correlation spectroscopies
(2016-12-20)
Article
Open AccessNon-invasive in vivo diffuse optical characterization of human bone opens a new possibility of diagnosing bone related pathologies. We present an in vivo characterization performed on seventeen healthy subjects at six ... -
Increased peripheral proinflammatory cytokines in HIV-1-infected patients with prolonged viral suppression suffering from high psychological stress
(2009-11)
Article
Restricted access - publisher's policy"In summary, patients who reported high levels of stress had significantly higher levels of peripheral proinflammatory cytokines, especially IL-6. The levels in our patients who reported stress averaged more than 6 times ... -
Interruptions of antiretroviral therapy in human immunodeficiency virus infection: are they detrimental to neurocognitive functioning?
(2010-06)
Article
Restricted access - publisher's policyBecause interruptions of antiretroviral treatment may entail clinical risks for human immunodeficiency virus (HIV)-infected individuals, we investigated their impact on neurocognitive functioning. Cross-sectional study ... -
Monotherapy with boosted PIs as an ART simplification strategy in clinical practice
(2015-04-01)
Article
Restricted access - publisher's policyBackground: Data on the efficacy of simplifying therapy using darunavir/ritonavir and lopinavir/ritonavir monotherapy in clinical practice remain limited.; Methods: A retrospective single-centre study including patients ... -
Nadir CD4 T cell count as predictor and high CD4 T cell intrinsic apoptosis as final mechanism of poor CD4 T cell recovery in virologically suppressed HIV-infected patients: clinical implications
(2010-05-01)
Article
Open AccessBACKGROUND: Although antiretroviral therapy improves immune response, some human immunodeficiency virus-infected patients present unsatisfactory CD4 T cell recovery despite achieving viral suppression, resulting in increased ... -
Prospective study to assess progression of renal markers after interruption of tenofovir due to nephrotoxicity
(2016)
Article
Open AccessBackground. Prospective studies about the reversibility of tenofovir disoproxil fumarate- (TDF-) related renal impairment remain scarce. Methods. This is an observational prospective study including all patients that ... -
¿Qué es una red neuronal artificial?
(2021-07-29)
Audiovisual
Open AccessEl aprendizaje humano es autónomo debido a que tenemos un sistema de captación de información a través de los sentidos que es combinada usando las neuronas y permite generar conocimiento de nuestro entorno. Las redes ... -
Randomised study to assess the efficacy and safety of once-daily etravirine-based regimen as a switching strategy in HIV-infected patients receiving a protease inhibitor-containing regimen. Etraswitch study
(2014-02-04)
Article
Open AccessBackground: Etravirine (ETR) was approved for patients with virological failure and antiretroviral resistance mutations. It has also shown antiviral efficacy in antiretroviral-naive patients. However, data on the switching ... -
Time of progression to osteopenia/osteoporosis in chronically HIV-infected patients: screening DXA scan
(2012-10-08)
Article
Open AccessAlgorithms for bone mineral density (BMD) management in HIV-infected patients are lacking. Our objective was to assess how often a dual-energy x-ray absorptiometry (DXA) scan should be performed by assessing time of ... -
Withdrawing inactive NRTIs in HIV-1 subjects with suppressed viraemia: a randomized trial
(2016-04)
Article
Restricted access - publisher's policyExtensively pretreated subjects with virological failure (VF) may receive salvage regimens containing NRTIs with only residual or no activity. Once virological suppression is achieved, their contribution remains elusive. ... -
Young biostatisticians in Spain: career or race?
(Sociedad de Estadística e Investigación Operativa (SEIO), 2013-10)
Article
Restricted access - publisher's policyChallenges and new opportunities for the integration of biostatisticians in multidisciplinary teams are a major concern in the field. New forms of broader training in the life sciences, collaborations with other scientists, ...
