Exploració per autor "Walani, Nikhil"

Ara es mostren els items 1-7 de 7

    • A physical mechanism of TANGO1-mediated bulky cargo export 

      Raote, Ishier; Chabanon, Morgan; Walani, Nikhil; Arroyo Balaguer, Marino; Garcia-Parajo, Maria F.; Malhotra, Vivek; Campelo Aubarell, Felix (2020-11-10)
      Article
      Accés obert
      The endoplasmic reticulum (ER)-resident protein TANGO1 assembles into a ring around ER exit sites (ERES), and links procollagens in the ER lumen to COPII machinery, tethers, and ER-Golgi intermediate compartment (ERGIC) ...

    • A theory of ordering of elongated and curved proteins on membranes driven by density and curvature 

      Tozzi, Caterina; Walani, Nikhil; Le Roux, Anabel-Lise; Roca-cusachs Solere, Pere; Arroyo Balaguer, Marino (2021-02-02)
      Article
      Accés obert
      Cell membranes interact with a myriad of curvature-active proteins that control membrane morphology and are responsible for mechanosensation and mechanotransduction. Some of these proteins, such as those containing BAR ...

    • Caveolin-1 dolines form a distinct and rapid caveolae-independent mechanoadaptation system 

      Lolo, Fidel Nicolás; Walani, Nikhil; Seemann, Eric; Zalvidea, Dobryna; Pavón, Dácil María; Cojoc, Gheorghe; Zamai, Moreno; Viaris de Lesegno, Christine; Martínez de Benito, Fernando; Sánchez Álvarez, Miguel; Uriarte, Juan José; Echarri, Asier; Jiménez Carretero, Daniel; Escolano, Joan Carles; Sánchez Donoso, Susana Angélica; Arroyo Balaguer, Marino (Nature, 2022-12-21)
      Article
      Accés obert
      In response to diferent types and intensities of mechanical force, cells modulate their physical properties and adapt their plasma membrane (PM). Caveolae are PM nano-invaginations that contribute to mechanoadaptation, ...

    • Dynamic mechanochemical feedback between curved membranes and BAR protein self-organization 

      Le Roux, Anabel-Lise; Tozzi, Caterina; Walani, Nikhil; Quiroga Álvarez, Xarxa; Zalvidea, Dobryna; Trepat Guixer, Xavier; Staykova, M; Arroyo Balaguer, Marino; Roca-Cusachs, Pere (2021-11-12)
      Article
      Accés obert
      In many physiological situations, BAR proteins reshape membranes with pre-existing curvature (templates), contributing to essential cellular processes. However, the mechanism and the biological implications of this reshaping ...

    • Onsager’s variational principle in soft matter : introduction and application to the dynamics of adsorption of proteins onto fluid membranes 

      Arroyo Balaguer, Marino; Walani, Nikhil; Torres Sánchez, Alejandro; Kaurin, Dimitri Jean Antoine (Springer, 2018)
      Capítol de llibre
      Accés obert
      This book is the first collection of lipid-membrane research conducted by leading mechanicians and experts in continuum mechanics. It brings the overall intellectual framework afforded by modern continuum mechanics to bear ...

    • Out-of-equilibrium mechanochemistry and self-organization of fluid membranes interacting with curved proteins 

      Tozzi, Caterina; Walani, Nikhil; Arroyo Balaguer, Marino (2019-09-04)
      Article
      Accés obert
      The function of biological membranes is controlled by the interaction of the fluid lipid bilayer with various proteins, some of which induce or react to curvature. These proteins can preferentially bind or diffuse towards ...

    • The plasma membrane as a mechanochemical transducer 

      Le Roux, Anabel-Lise; Quiroga Álvarez, Xarxa; Walani, Nikhil; Arroyo Balaguer, Marino; Roca Cusachs, Pere (2019-07-01)
      Article
      Accés obert
      Cells are constantly submitted to external mechanical stresses, which they must withstand and respond to. By forming a physical boundary between cells and their environment that is also a biochemical platform, the plasma ...