Browsing by Author "Engel López, Elisabeth"
Now showing items 1-20 of 65
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3D silicon doped hydroxyapatite scaffolds decorated with Elastin-like Recombinamers for bone regenerative medicine
Vila, Mercedes; García, Ana; Girotti, Alessandra; Alonso, Matilde; Rodriguez Cabello, Jose Carlos; Gonzalez Vazquez, Arlyng; Planell Estany, Josep Anton; Engel López, Elisabeth; Buján, Julia; García Honduvilla, Natalio; Vallet Regi, Maria (2016-11-01)
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Open AccessThe current study reports on the manufacturing by rapid prototyping technique of three-dimensional (3D) scaffolds based on silicon substituted hydroxyapatite with Elastin-like Recombinamers (ELRs) functionalized surfaces. ... -
A bioactive elastin-like recombinamer reduces unspecific protein adsorption and enhances cell response on titanium surfaces.
Salvagni, Emiliano; Berguig, Geoffrey; Engel López, Elisabeth; Rodriguez Cabello, Jose Carlos; Coullerez, Geraldine; Textor, Marcus; Planell Estany, Josep Anton; Gil Mur, Francisco Javier; Aparicio Bádenas, Conrado José (2013-10-17)
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Covenantee: University of Minnesota School of Dentistry / Universidad de ValladolidWe present the immobilization on synthetic substrates of elastin-like recombinamers (ELR) that combine a bioactive motif for cell adhesion with protein antifouling properties. Physical adsorption of the recombinamers and ... -
A novel hybrid nanofibrous strategy to target progenitor cells for cost-effective in situ angiogenesis
Sachot, Nadège; Castaño Linares, Óscar; Oliveira, Hugo; Martí Muñoz, Joan; Roguska, Agata; Amedee, Joelle; Lewandowska, Malgorzata; Planell Estany, Josep Anton; Engel López, Elisabeth (Royal Society of Chemistry, 2016-11-02)
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Open AccessAlthough the impact of composites based on Ti-doped calcium phosphate glasses is low compared with that of bioglass, they have been already shown to possess great potential for bone tissue engineering. Composites made of ... -
A novel hybrid nanofibrous strategy to target progenitor cells for cost-effective: In situ angiogenesis
Sachot, Nadege; Castaño Linares, Óscar; Oliveira, Hugo; Martí Muñoz, Joan; Roguska, Agata; Amedee, Joelle; Lewandowska, Malgorzata; Planell Estany, Josep Anton; Engel López, Elisabeth (Royal Society of Chemistry, 2016-09-22)
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Open AccessAlthough the impact of composites based on Ti-doped calcium phosphate glasses is low compared with that of bioglass, they have been already shown to possess great potential for bone tissue engineering. Composites made of ... -
Alendronate and etidronate do not regulate interleukin 6 and 11 synthesis in normal human osteoblasts in culture
Engel López, Elisabeth; Serrano, Sergi; Mariñoso, Maria Lluïsa; Lloreta, Josep; Ulloa, Fausto; Nogués, Xavier; Díez-Pérez, Adolfo; Carbonell, Jordi (2003)
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Open AccessBisphosphonates exert a potent inhibitory effect on bone resorption. Several studies have been performed, with contradictory results, to ascertain whether the effect of bisphosphonates on osteoclasts could be produced, ... -
An efficient and reproducible method to culture Bergmann and cortical radial glia using textured PMMA
Álvarez Pinto, Zaída; Sena, Elena; Mattotti, Marta; Engel López, Elisabeth; Alcantara, Soledad (2014-07-30)
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Restricted access - publisher's policyRadial glia cells comprise the principal population of neural stem cells (NSC) during development. Attempts to develop reproducible radial glia and NSC culture methods have met with variable results, yielding non-adherent ... -
Angiogenesis in bone regeneration: tailored calcium release in hybrid fibrous scaffolds
Castaño Linares, Óscar; Sachot, Nadège; Xuriguera Martin, Elena; Engel López, Elisabeth; Planell Estany, Josep Anton; Park, Jaegyun; Jin, Guang-Zhen; Kim, Tae-Hyun; Kim, Joong-Hyun; Kim, Hae-Won (2014-05-28)
Article
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Covenantee: Tan'guk TaehakkyoIn bone regeneration, silicon-based calcium phosphate glasses (Bioglasses) have been widely used since the 1970s. However, they dissolve very slowly because of their high amount of Si (SiO2 > 45%). Recently, our group has ... -
Biomimetic treatments on dental implants for immediate loading applications
Gil Mur, Francisco Javier; Aparicio Bádenas, Conrado José; Salvagni, Emiliano; Werner, Michael; Engel López, Elisabeth; Pegueroles Neyra, Marta; Rodriguez-Cabello, C.; Munoz, F; Planell Estany, Josep Anton (2009-06)
Article
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Covenantee: Universidad de ValladolidCommercially pure titanium (cp Ti) dental implants have been widely and successfully used with high rates of clinical success in normal situations. However, there is still a lack of reliable synthetic materials to be used ... -
Chitosan/PEGDA based scaffolds as bioinspired materials to control in vitro angiogenesis
Soriente, Alessandra; Pérez Amodio, Soledad Graciela; Fasolino, Ines; Raucci, Maria Grazia; Demitri, Christian; Engel López, Elisabeth; Ambrosio, Luigi (Elsevier, 2021-01-01)
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Restricted access - publisher's policyIn the current work, our purpose was based on the assessment of bioactive chitosan (CS)/Poly(ethylene glycol) diacrylate (PEGDA) based scaffolds ability to stimulate in vitro angiogenesis process. The bioactivation of the ... -
Chondroinductive alginate-based hydrogels having graphene oxide for 3D printed scaffold fabrication
Olate Moya, Felipe; Mateos Timoneda, Miguel Ángel; Engel López, Elisabeth; Arens, Lukas; Wilhelm, Manfred; Palza, Humberto (2020-01-07)
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Open AccessScaffolds based on bioconjugated hydrogels are attractive for tissue engineering because they can partly mimic human tissue characteristics. For example, they can further increase their bioactivity with cells. However, ... -
Co-assembled and microfabricated bioactive membranes
Mendes, Ana C.; Smith, Katherine H.; Tejeda Montes, Esther; Engel López, Elisabeth; Reis, Rui L.; Azevedo, Elena S.; Mata, Álvaro (2012-09-03)
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Restricted access - publisher's policyThe fabrication of hierarchical and bioactive self-supporting membranes, which integrate physical and biomolecular elements, using a single-step process that combines molecular self-assembly with soft lithography ... -
Control of microenvironmental cues with a smart biomaterial composite promotes endothelial progenitor cell angiogenesis
Aguirre, Adrián; Gonzalez, Arlyng; Navarro, Melba; Castaño Linares, Óscar; Planell Estany, Josep Anton; Engel López, Elisabeth (2012-09)
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Open AccessSmart biomaterials play a key role when aiming at successful tissue repair by means of regenerative medicine approaches, and are expected to contain chemical as well as mechanical cues that will guide the regenerative ... -
Development of a novel automatable fabrication method based on electrospinning co electrospraying for rotator cuff augmentation patches
Rey Viñoles, Sergi; Castaño Linares, Óscar; Ruiz Macarrilla, Leonardo; Llorens, Xavier; Mora Guix, José M.; Engel López, Elisabeth; Mateos Timoneda, Miguel Ángel (Public Library of Science (PLOS), 2019-01-01)
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Open AccessRotator cuff tear is one of the most common shoulder diseases. Rotator cuff augmentation (RCA) is trying to solve the high retear failure percentage after the surgery procedures (20–90%). The ideal augmentation patch must ... -
Development of a self-assembled peptide/methylcellulose-based bioink for 3D bioprinting
Cofiño, Carla; Pérez Amodio, Soledad Graciela; Semino, Carlos; Engel López, Elisabeth; Mateos Timoneda, Miguel Ángel (2019-11-13)
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Open AccessThe introduction of 3D bioprinting to fabricate living constructs with tailored architecture has provided a new paradigm for biofabrication, with the potential to overcome several drawbacks of conventional scaffold-based ... -
Development of a three-dimensional bioengineered platform for articular cartilage regeneration
Rubi Sans, Gerard; Recha Sancho, Lourdes; Pérez Amodio, Soledad Graciela; Mateos Timoneda, Miguel Ángel; Semino Margrett, Carlos Eduardo; Engel López, Elisabeth (2020-01-01)
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Open AccessDegenerative cartilage pathologies are nowadays a major problem for the world population. Factors such as age, genetics or obesity can predispose people to suffer from articular cartilage degeneration, which involves severe ... -
Development of tailored and self-mineralizing citric acid-crosslinked hydrogels for in situ bone regeneration
Sanchez Ferrero, Aitor; Mata, Álvaro; Mateos Timoneda, Miguel Ángel; Rodriguez Cabello, Jose Carlos; Alonso, Matilde; Planell Estany, Josep Anton; Engel López, Elisabeth (2015-11-01)
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Open Access
Covenantee: Universidad de ValladolidBone tissue engineering demands alternatives overcoming the limitations of traditional approaches in the context of a constantly aging global population. In the present study, elastin-like recombinamers hydrogels were ... -
Differential neuronal and glial behavior on flat and micro patterned chitosan films
Mattotti, Marta; Álvarez Pinto, Zaída; Delgado Muñoz, Luis; Mateos Timoneda, Miguel Ángel; Aparicio, Conrado; Planell Estany, Josep Anton; Alcántara Horrillo, Soledad; Engel López, Elisabeth (2017-10-01)
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Open AccessChitosan is a biodegradable natural polysaccharide that has been widely studied for regenerative purposes in the central nervous system. In this study we assessed the in vitro glial and neuronal cells response to chitosan ... -
Directional alignment of MG63 cells on polymer surfaces containing point microstructures
Christopher, A Mills; Fernandez, Javier G; Martinez, Elena; Miriam, Funes; Engel López, Elisabeth; Abdelhamid, Errachid; Planell Estany, Josep Anton; Samitier Martí, Josep (2007-05)
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Open AccessMG63 cells cultured on regular arrays of point microstructures (posts and holes) are shown to preferentially align at certain angles to the pattern of the structures, at 08, 308, and 458 in particular. The effect is found ... -
Disassembling bacterial extracellular matrix with DNase-coated nanoparticles to enhance antibiotic delivery in biofilm infections
Baelo, Aida; Levato, Riccardo; Julian, Esther; Crespo, A.; Astola, Jose; Gavalda, Joan; Engel López, Elisabeth; Mateos Timoneda, Miguel Ángel; Torrents, Eduard (2015-07-10)
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Open Access
Covenantee: Hospital Universitari Vall d'HebronInfections caused by biofilm-forming bacteria are a major threat to hospitalized patients and the main cause of chronic obstructive pulmonary disease and cystic fibrosis. There is an urgent necessity for novel therapeutic ... -
Effect of blasting treatment and Fn coating on MG63 adhesion and differentiation on titanium: A gene expression study using real-time RT-PCR
Pegueroles Neyra, Marta; Aguirre Cano, Aitor; Engel López, Elisabeth; Pavon-Djavid, Graciela; Gil Mur, Francisco Javier; Planell Estany, Josep Anton; Migonney, Veronique; Aparicio Bádenas, Conrado José (2011-03)
Article
Restricted access - publisher's policyBiomaterial surface properties, via alterations in the adsorbed protein layer, and the presence of specific functional groups can influence integrin binding specificity, thereby modulating cell adhesion and differentiation ...