Now showing items 1-20 of 54

  • 3D silicon doped hydroxyapatite scaffolds decorated with Elastin-like Recombinamers for bone regenerative medicine 

    Vila, Mercedes; García, Ana; Girotti, Alessandra; Alonso, Matilde; Rodriguez Cabello, Jose Carlos; Gonzalez Vazquez, Arlyng; Planell Estany, Josep Anton; Engel López, Elisabeth; Buján, Julia; García Honduvilla, Natalio; Vallet Regi, Maria (2016-11-01)
    Article
    Open Access
    The current study reports on the manufacturing by rapid prototyping technique of three-dimensional (3D) scaffolds based on silicon substituted hydroxyapatite with Elastin-like Recombinamers (ELRs) functionalized surfaces. ...
  • A bioactive elastin-like recombinamer reduces unspecific protein adsorption and enhances cell response on titanium surfaces. 

    Salvagni, Emiliano; Berguig, Geoffrey; Engel López, Elisabeth; Rodriguez Cabello, Jose Carlos; Coullerez, Geraldine; Textor, Marcus; Planell Estany, Josep Anton; Gil Mur, Francisco Javier; Aparicio Bádenas, Conrado José (2013-10-17)
    Article
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    Covenantee:  University of Minnesota School of Dentistry / Universidad de Valladolid
    We present the immobilization on synthetic substrates of elastin-like recombinamers (ELR) that combine a bioactive motif for cell adhesion with protein antifouling properties. Physical adsorption of the recombinamers and ...
  • Alendronate and etidronate do not regulate interleukin 6 and 11 synthesis in normal human osteoblasts in culture 

    Engel López, Elisabeth; Serrano, Sergi; Mariñoso, Maria Lluïsa; Lloreta, Josep; Ulloa, Fausto; Nogués, Xavier; Díez-Pérez, Adolfo; Carbonell, Jordi (2003)
    Article
    Open Access
    Bisphosphonates exert a potent inhibitory effect on bone resorption. Several studies have been performed, with contradictory results, to ascertain whether the effect of bisphosphonates on osteoclasts could be produced, ...
  • An efficient and reproducible method to culture Bergmann and cortical radial glia using textured PMMA 

    Álvarez Pinto, Zaída; Sena, Elena; Mattotti, Marta; Engel López, Elisabeth; Alcantara, Soledad (2014-07-30)
    Article
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    Radial glia cells comprise the principal population of neural stem cells (NSC) during development. Attempts to develop reproducible radial glia and NSC culture methods have met with variable results, yielding non-adherent ...
  • Angiogenesis in bone regeneration: tailored calcium release in hybrid fibrous scaffolds 

    Castaño Linares, Óscar; Sachot, Nadège; Xuriguera Martin, Elena; Engel López, Elisabeth; Planell Estany, Josep Anton; Park, Jaegyun; Jin, Guang-Zhen; Kim, Tae-Hyun; Kim, Joong-Hyun; Kim, Hae-Won (2014-05-28)
    Article
    Restricted access - publisher's policy
    Covenantee:  Tan'guk Taehakkyo
    In bone regeneration, silicon-based calcium phosphate glasses (Bioglasses) have been widely used since the 1970s. However, they dissolve very slowly because of their high amount of Si (SiO2 > 45%). Recently, our group has ...
  • A novel hybrid nanofibrous strategy to target progenitor cells for cost-effective in situ angiogenesis 

    Sachot, Nadège; Castaño Linares, Óscar; Oliveira, Hugo; Martí Muñoz, Joan; Roguska, Agata; Amedee, Joelle; Lewandowska, Malgorzata; Planell Estany, Josep Anton; Engel López, Elisabeth (Royal Society of Chemistry, 2016-11-02)
    Article
    Open Access
    Although the impact of composites based on Ti-doped calcium phosphate glasses is low compared with that of bioglass, they have been already shown to possess great potential for bone tissue engineering. Composites made of ...
  • A novel hybrid nanofibrous strategy to target progenitor cells for cost-effective: In situ angiogenesis 

    Sachot, Nadege; Castaño Linares, Óscar; Oliveira, Hugo; Martí Muñoz, Joan; Roguska, Agata; Amedee, Joelle; Lewandowska, Malgorzata; Planell Estany, Josep Anton; Engel López, Elisabeth (Royal Society of Chemistry, 2016-09-22)
    Article
    Open Access
    Although the impact of composites based on Ti-doped calcium phosphate glasses is low compared with that of bioglass, they have been already shown to possess great potential for bone tissue engineering. Composites made of ...
  • Biomimetic treatments on dental implants for immediate loading applications 

    Gil Mur, Francisco Javier; Aparicio Bádenas, Conrado José; Salvagni, Emiliano; Werner, Michael; Engel López, Elisabeth; Pegueroles Neyra, Marta; Rodriguez-Cabello, C.; Munoz, F; Planell Estany, Josep Anton (2009-06)
    Article
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    Covenantee:  Universidad de Valladolid
    Commercially pure titanium (cp Ti) dental implants have been widely and successfully used with high rates of clinical success in normal situations. However, there is still a lack of reliable synthetic materials to be used ...
  • Co-assembled and microfabricated bioactive membranes 

    Mendes, Ana C.; Smith, Katherine H.; Tejeda Montes, Esther; Engel López, Elisabeth; Reis, Rui L.; Azevedo, Elena S.; Mata, Álvaro (2012-09-03)
    Article
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    The fabrication of hierarchical and bioactive self-supporting membranes, which integrate physical and biomolecular elements, using a single-step process that combines molecular self-assembly with soft lithography ...
  • Control of microenvironmental cues with a smart biomaterial composite promotes endothelial progenitor cell angiogenesis 

    Aguirre, Adrián; Gonzalez, Arlyng; Navarro, Melba; Castaño Linares, Óscar; Planell Estany, Josep Anton; Engel López, Elisabeth (2012-09)
    Article
    Open Access
    Smart biomaterials play a key role when aiming at successful tissue repair by means of regenerative medicine approaches, and are expected to contain chemical as well as mechanical cues that will guide the regenerative ...
  • Development of tailored and self-mineralizing citric acid-crosslinked hydrogels for in situ bone regeneration 

    Sanchez Ferrero, Aitor; Mata, Álvaro; Mateos Timoneda, Miguel Ángel; Rodriguez Cabello, Jose Carlos; Alonso, Matilde; Planell Estany, Josep Anton; Engel López, Elisabeth (2015-11-01)
    Article
    Open Access
    Covenantee:  Universidad de Valladolid
    Bone tissue engineering demands alternatives overcoming the limitations of traditional approaches in the context of a constantly aging global population. In the present study, elastin-like recombinamers hydrogels were ...
  • Differential neuronal and glial behavior on flat and micro patterned chitosan films 

    Mattotti, Marta; Álvarez Pinto, Zaída; Delgado Muñoz, Luis; Mateos Timoneda, Miguel Ángel; Aparicio, Conrado; Planell Estany, Josep Anton; Alcántara Horrillo, Soledad; Engel López, Elisabeth (2017-10-01)
    Article
    Open Access
    Chitosan is a biodegradable natural polysaccharide that has been widely studied for regenerative purposes in the central nervous system. In this study we assessed the in vitro glial and neuronal cells response to chitosan ...
  • Directional alignment of MG63 cells on polymer surfaces containing point microstructures 

    Christopher, A Mills; Fernandez, Javier G; Martinez, Elena; Miriam, Funes; Engel López, Elisabeth; Abdelhamid, Errachid; Planell Estany, Josep Anton; Samitier Martí, Josep (2007-05)
    Article
    Open Access
    MG63 cells cultured on regular arrays of point microstructures (posts and holes) are shown to preferentially align at certain angles to the pattern of the structures, at 08, 308, and 458 in particular. The effect is found ...
  • Disassembling bacterial extracellular matrix with DNase-coated nanoparticles to enhance antibiotic delivery in biofilm infections 

    Baelo, Aida; Levato, Riccardo; Julian, Esther; Crespo, A.; Astola, Jose; Gavalda, Joan; Engel López, Elisabeth; Mateos Timoneda, Miguel Ángel; Torrents, Eduard (2015-07-10)
    Article
    Open Access
    Covenantee:  Hospital Universitari Vall d'Hebron
    Infections caused by biofilm-forming bacteria are a major threat to hospitalized patients and the main cause of chronic obstructive pulmonary disease and cystic fibrosis. There is an urgent necessity for novel therapeutic ...
  • Effect of blasting treatment and Fn coating on MG63 adhesion and differentiation on titanium: A gene expression study using real-time RT-PCR 

    Pegueroles Neyra, Marta; Aguirre Cano, Aitor; Engel López, Elisabeth; Pavon-Djavid, Graciela; Gil Mur, Francisco Javier; Planell Estany, Josep Anton; Migonney, Veronique; Aparicio Bádenas, Conrado José (2011-03)
    Article
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    Biomaterial surface properties, via alterations in the adsorbed protein layer, and the presence of specific functional groups can influence integrin binding specificity, thereby modulating cell adhesion and differentiation ...
  • Effect of blasting treatment and Fn coating on MG63 adhesion and differentiation on titanium: a gene expression study using real-time RT-PCR. 

    Pegueroles Neyra, Marta; Aguirre Cano, Aitor; Engel López, Elisabeth; Pavon-Djavid, Graciela; Gil Mur, Francisco Javier; Planell Estany, Josep Anton; Migonney, Veronique; Aparicio Bádenas, Conrado José (2011-03-02)
    Article
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    Biomaterial surface properties, via alterations in the adsorbed protein layer, and the presence of specific functional groups can influence integrin binding specificity, thereby modulating cell adhesion and differentiation ...
  • Effect of structure, topography and chemistry on fibroblast adhesion and morphology 

    Mateos Timoneda, Miguel Ángel; Castaño Linares, Óscar; Planell Estany, Josep Anton; Engel López, Elisabeth (2014-07)
    Article
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    Surface biofunctionalisation of many biodegradable polymers is one of the used strategies to improve the biological activity of such materials. In this work, the introduction of collagen type I over the surface of a ...
  • Effects of artificial micro- and nano-structured surfaces on cell behaviour 

    Martínez, E.; Engel López, Elisabeth; Planell Estany, Josep Anton; Samitier Martí, Josep (2009)
    Article
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  • Electrochemical microelectrodes for improved spatial and temporal characterization of aqueous environments around calcium phosphate cements. 

    Gustavsson, Johan; Ginebra Molins, Maria Pau; Planell Estany, Josep Anton; Engel López, Elisabeth (2011-10-07)
    Article
    Restricted access - publisher's policy
    Calcium phosphate compounds can potentially influence cellular fate through ionic substitutions. However, to be able to turn such solution-mediated processes into successful directors of cellular response, a perfect ...
  • Electrospun conducting and biocompatible uniaxial and core-shell fibers having Poly(lactic acid), Poly(ethylene glycol), and Polyaniline for cardiac tissue engineering 

    Bertuoli, Paula T.; Ordoño Fernández, Jesús; Armelín Diggroc, Elaine Aparecida; Pérez Amodio, Soledad Graciela; Baldissera, A. F.; Ferreira, Carlos A.; Puiggalí Bellalta, Jordi; Engel López, Elisabeth; Valle Mendoza, Luis Javier del; Alemán Llansó, Carlos (American Chemical Society (ACS), 2019-02-19)
    Article
    Open Access