Peptide delta-turn: Literature survey and recent progress
Rights accessOpen Access
Among the various types of a-peptide folding motifs, delta-turn, which requires a central cis-amide disposition, has been one of the least extensively investigated. In particular, this main-chain reversal topology has been studied in-depth neither in linear/cyclic peptides nor in proteins. This Minireview article assembles and critically analyzes relevant data from a literature survey on the d-turn conformation in those compounds. Unpublished results from recent conformational energy calculations and a preliminary solution-state analysis on a small model peptide, currently ongoing in our laboratories, are also briefly outlined.
CitationToniolo, C., Crisma, M., Moretto, A., peggion, C., Formaggio, F., Aleman, C., Cativiela, C., Ramakrishnan, C., Balaram, P. Peptide delta-turn: Literature survey and recent progress. "Chemistry: a european journal", 28 Setembre 2015, vol. 21, núm. 40, p. 13866-13877.