Enviaments recents

  • Microbiome datasets are compositional: and this is not optional 

    Gloor, Gregory B.; Macklaim, Jean M.; Pawlowsky Glahn, Vera; Egozcue Rubí, Juan José (2017-11)
    Article
    Accés obert
    Datasets collected by high-throughput sequencing (HTS) of 16S rRNA gene amplimers, metagenomes or metatranscriptomes are commonplace and being used to study human disease states, ecological differences between sites, and ...
  • A bayesian test for Hardy-Weinberg equilibrium of bi-allelic X-chromosomal markers 

    Puig Oriol, Xavier; Ginebra Molins, Josep; Graffelman, Jan (2017-07)
    Article
    Accés obert
    The X chromosome is a relatively large chromosome, harboring a lot of genetic information. Much of the statistical analysis of X-chromosomal information is complicated by the fact that males only have one copy. Recently, ...
  • A genome-wide study of Hardy–Weinberg equilibrium with next generation sequence data 

    Graffelman, Jan; Jain, Deepti; Weir, B.S. (2017-04-03)
    Article
    Accés obert
    Statistical tests for Hardy–Weinberg equilibrium have been an important tool for detecting genotyping errors in the past, and remain important in the quality control of next generation sequence data. In this paper, we ...
  • Graphics for relatedness research 

    Galván Femenía, Iván; Graffelman, Jan; Barceló Vidal, Carles (Wiley, 2017-04-03)
    Article
    Accés obert
    Studies of relatedness have been crucial in molecular ecology over the last decades. Good evidence of this is the fact that studies of population structure, evolution of social behaviours, genetic diversity and quantitative ...
  • Multivariate statistical modelling of future marine storms 

    Lin Ye, Jue; García León, Manuel; Gracia Garcia, Vicente; Ortego Martínez, María Isabel; Lionello, Piero; Sánchez-Arcilla Conejo, Agustín (2017-04)
    Article
    Accés restringit per política de l'editorial
    Extreme events, such as wave-storms, need to be characterized for coastal infrastructure design purposes. Such description should contain information on both the univariate behaviour and the joint-dependence of storm-variables. ...
  • Compositional data for global monitoring: the case of drinking water and sanitation 

    Pérez Foguet, Agustí; Giné Garriga, Ricard; Ortego Martínez, María Isabel (2017-07)
    Article
    Accés restringit per política de l'editorial
    Introduction At a global level, access to safe drinking water and sanitation has been monitored by the Joint Monitoring Programme (JMP) of WHO and UNICEF. The methods employed are based on analysis of data from household ...
  • Update: A non-parametric method for the measurement of size diversity, with emphasis on data standardization. The measurement of the size evenness 

    Quintana Pou, Francisco Javier de; Egozcue Rubí, Juan José; Martinez Abella, Omar; Lopez Florez, Rocio; Gascon, Stephanie; Brucet, Sandra; Boix, Daniel (2016-06)
    Article
    Accés obert
    A method for the measurement of the size diversity based on the classical Shannon–Wiener expression was proposed as a proxy of the shape of the size distribution. The summatory of probabilities of a discrete variable (such ...
  • Bayesian estimation of the orthogonal decomposition of a contingency table 

    Ortego Martínez, María Isabel; Egozcue Rubí, Juan José (2016)
    Article
    Accés obert
    In a multinomial sampling, contingency tables can be parametrized by probabilities of each cell. These probabilities constitute the joint probability function of two or more discrete random variables. These probability ...
  • Air quality index revisited from a compositional point of view 

    Jarauta Bragulat, Eusebio; Hervada Sala, Carme; Egozcue Rubí, Juan José (2016-06)
    Article
    Accés obert
    The so-called Air Quality Index (AQI), expresses the quality of atmospheric air. The overall AQI is determined from the AQIs of some reference air pollutants, which are calculated by a transform of the respective concentrations. ...
  • Proportionality: a valid alternative to correlation for relative data 

    Lovell, David; Pawlowsky-Glahn, Vera; Egozcue Rubí, Juan José; Marguerat, Samuel; Baehler, Juerg (2015-03-01)
    Article
    Accés obert
    In the life sciences, many measurement methods yield only the relative abundances of different components in a sample. With such relative-or compositional-data, differential expression needs careful interpretation, and ...
  • Spatial analysis of compositional data : a historical review 

    Pawlowsky-Glahn, Vera; Egozcue Rubí, Juan José (2016-05-01)
    Article
    Accés restringit per política de l'editorial
    Like the statistical analysis of compositional data in general, spatial analysis of compositional data requires specific tools. A historical overview of their development is presented in three steps: (a) the recognition ...
  • Testing for Hardy–Weinberg equilibrium at biallelic genetic markers on the X chromosome 

    Graffelman, Jan; Weir, B.S. (2016-04-13)
    Article
    Accés obert
    Testing genetic markers for Hardy–Weinberg equilibrium (HWE) is an important tool for detecting genotyping errors in large-scale genotyping studies. For markers at the X chromosome, typically the ¿2 or exact test is applied ...

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