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Tabu search for the founder sequence reconstruction problem: a preliminary study
dc.contributor.author | Roli, Andrea |
dc.contributor.author | Blum, Christian |
dc.contributor.other | Universitat Politècnica de Catalunya. Departament de Llenguatges i Sistemes Informàtics |
dc.date.accessioned | 2010-05-05T12:04:08Z |
dc.date.available | 2010-05-05T12:04:08Z |
dc.date.created | 2009 |
dc.date.issued | 2009 |
dc.identifier.citation | Roli, A.; Blum, C. Tabu search for the founder sequence reconstruction problem: a preliminary study. "Lecture notes in computer science", 2009, vol. 5518, p. 1035-1042. |
dc.identifier.issn | 0302-9743 |
dc.identifier.uri | http://hdl.handle.net/2117/7130 |
dc.description.abstract | The problem of inferring ancestral genetic information in terms of a set of founders of a given population arises in various biological contexts. In optimization terms, this problem can be formulated as a combinatorial string problem. The main problem of existing techniques, both exact and heuristic, is that their time complexity scales exponentially, which makes them impractical for solving large-scale instances. We developed a new constructive heuristic and a tabu search method with the explicit aim of providing solutions in a reduced amount of computation time. Experimental results show that when the number of founders grows, our algorithms have advantages over the ones proposed in the literature. |
dc.format.extent | 8 p. |
dc.language.iso | eng |
dc.subject | Àrees temàtiques de la UPC::Informàtica::Intel·ligència artificial |
dc.subject.lcsh | Heuristic programming |
dc.title | Tabu search for the founder sequence reconstruction problem: a preliminary study |
dc.type | Article |
dc.subject.lemac | Programació heurística |
dc.contributor.group | Universitat Politècnica de Catalunya. ALBCOM - Algorismia, Bioinformàtica, Complexitat i Mètodes Formals |
dc.identifier.doi | 10.1007/978-3-642-02481-8_157 |
dc.description.peerreviewed | Peer Reviewed |
dc.rights.access | Restricted access - publisher's policy |
local.identifier.drac | 2318233 |
dc.description.version | Postprint (published version) |
local.citation.author | Roli, A.; Blum, C. |
local.citation.publicationName | Lecture notes in computer science |
local.citation.volume | 5518 |
local.citation.startingPage | 1035 |
local.citation.endingPage | 1042 |
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