Enviaments recents

  • Effect of the solvent on the conformational behavior of the alanine dipeptide deduced from MD simulations 

    Rubio Martínez, Jaime; Tomás Belenguer, María Santos; Pérez González, Juan Jesús (2017-11-01)
    Article
    Accés obert
    In general, peptides do not exhibit a well-defined conformational profile in solution. However, despite the experimental blurred picture associated with their structure, compelling spectroscopic evidence shows that peptides ...
  • Hydrogel dressings for advanced wound management 

    Francesko, Antonio; Petkova, Petya; Tzanov, Tzanko (2017-09-20)
    Article
    Accés restringit per política de l'editorial
    Composed in a large extent of water and due to their non-adhesiveness, hydrogels found their way to the wound dressing market as materials that provide a moisture environment for healing while being comfortable to the ...
  • Using molecular dynamics for the refinement of atomistic models of GPCRs by homology modeling 

    Lupala, Cecylia Severin; Rasaeifar, Bahareh; Gómez Gutiérrez, Patricia; Pérez González, Juan Jesús (2017-08-13)
    Article
    Accés restringit per política de l'editorial
    Despite GPCRs sharing a common seven helix bundle, analysis of the diverse crystallographic structures available reveal specific features that might be relevant for ligand design. Despite the number of crystallographic ...
  • Flavonoid allosteric modulation of mutated visual rhodopsin associated with retinitis pigmentosa 

    Herrera Hernández, María Guadalupe; Ramon Portés, Eva; Lupala, Cecylia Severin; Tena Campos, Mercè; Pérez González, Juan Jesús; Garriga Solé, Pere (Macmillan Publishers, 2017-12-01)
    Article
    Accés obert
    Dietary flavonoids exhibit many biologically-relevant functions and can potentially have beneficial effects in the treatment of pathological conditions. In spite of its well known antioxidant properties, scarce structural ...
  • Structural study of a new HIV-1 entry inhibitor and interaction with the HIV-1 fusion peptide in dodecylphosphocholine micelles 

    Pérez González, Juan Jesús; Pérez, Yolanda; Gómara, Maria José; Yuste, Eloísa; Gómez Gutierrez, Patricia; Haro, Isabel (2017-07-03)
    Article
    Accés restringit per política de l'editorial
    Previous studies support the hypothesis that the envelope GB virus C (GBV-C) E1 protein interferes the HIV-1 entry and that a peptide, derived from the region 139-156 of this protein, has been defined as a novel HIV-1 entry ...
  • Structural and functional alterations associated with deutan N94K and R330Q mutations of green cone opsin 

    Srinivasan, Sundaramoorthy; Fernández Sampedro, Miguel Antonio; Ramon Portés, Eva; Garriga Solé, Pere (2017-07-01)
    Article
    Accés restringit per política de l'editorial
    Deuteranopia is an X-linked congenital dichromatic condition in which single point mutations in green cone opsin lead to defective non-functional cone photoreceptor cells. Green cone opsin belongs to the G protein-coupled ...
  • Sonochemical synthesis and stabilization of concentrated antimicrobial silver-chitosan nanoparticle dispersions 

    Francesko, Antonio; Petkova, Petya; Mendoza Gómez, Ernesto; Tzanov, Tzanko (Wiley, 2017-08)
    Article
    Accés restringit per política de l'editorial
    This work reports on a green synthetic route to produce concentrated aqueous dispersions of silver nanoparticles (AgNP) employing high-intensity ultrasound (US) and chitosan (CS) as a non-toxic reducing agent for Ag1 salts ...
  • Multifunctional enzymatically generated hydrogels for chronic wound application 

    Stefanov, Ivaylo; Hoyo Pérez, Javier; Cailloux, Jonathan; Santana Pérez, Orlando Onofre; Tzanov, Tzanko (2017-04-19)
    Article
    Accés restringit per política de l'editorial
    The healing of chronic wounds requires intensive medical intervention at huge healthcare costs. Dressing materials should consider the multifactorial nature of these wounds comprising deleterious proteolytic and oxidative ...
  • Nanotransformation of vancomycin overcomes the intrinsic resistance of Gram-negative bacteria 

    Ivanova, Kristina Dimitrova; Hoyo Pérez, Javier; Francesko, Antonio; Tzanov, Tzanko (2017-04-10)
    Article
    Accés restringit per política de l'editorial
    The increased emergence of antibiotic-resistant bacteria is a growing public health concern, and although new drugs are constantly being sought, the pace of development is slow compared with the evolution and spread of ...
  • Hybrid chitosan-silver nanoparticles enzymatically-embedded on cork filter material for water disinfection 

    Garcia Peña, Lina Vanesa; Petkova, Petya; Margalef-Marti, Rosanna; Vives, Marc; Aguilar, Lorena; Gallegos, Angel; Francesko, Antonio; Perelshtein, Ilana; Gedanken, Aharon; Mendoza Gómez, Ernesto; Casas-Zapata, Juan Carlos; Morató Farreras, Jordi; Tzanov, Tzanko (2017-04-05)
    Article
    Accés restringit per política de l'editorial
    Microbial contamination remains a major challenge in supply of drinking water in developing regions, despite the continuous advances being made in water purification processes. The spread and transmission of pathogens due ...

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