El grup de recerca treballa en el camp de l'estructura-funció de proteïnes d'interès biomèdic i biotecnològic. Es porta a terme el disseny i l?obtenció de proteïnes recombinants mitjançant tècniques d'enginyeria genètica. Aquestes proteïnes són purificades i caracteritzades per tècniques bioquímiques i espectroscòpiques. També es treballa en la modificació d'enzims per a aplicacions en processos biotecnològics d'interès industrial.

http://futur.upc.edu/GBMI

The research group works on the structure and function of proteins of biomedical and biotechnological relevance. Recombinant proteins are designed and obtained by means of genetic engineering techniques. These proteins are purified and characterised using biochemical and spectroscopic methods. Enzyme engineering and modification are also studied, for their application to biotechnological processes in industry.

http://futur.upc.edu/GBMI

The research group works on the structure and function of proteins of biomedical and biotechnological relevance. Recombinant proteins are designed and obtained by means of genetic engineering techniques. These proteins are purified and characterised using biochemical and spectroscopic methods. Enzyme engineering and modification are also studied, for their application to biotechnological processes in industry.

http://futur.upc.edu/GBMI

Enviaments recents

  • Review on bibliography related to antimicrobials 

    Torrent Burgués, Juan (2017-02-09)
    Report de recerca
    Accés obert
    In this report, a bibliographic research has been done in the field of antimicrobials. Not all antimicrobials have been included, but those that are being subject of matter in the group GBMI in Terrassa, and others of ...
  • Innovative approaches for controlling clinically relevant biofilms: current trends and future prospects 

    Ivanova, Kristina Dimitrova; Tzanov, Tzanko (2017-01-05)
    Article
    Accés obert
    Bacteria that colonize and form biofilms on living tissues and medical devices are a global healthcare concern. They cause life threatening infections and are associated with increased mortality and morbidity in the ...
  • Identification of a novel inhibitory allosteric site of MAP kinases 

    Gomez-Gutierrez, Patricia; Campos Muelas, Pedro Manuel; Vega, Miguel; Pérez González, Juan Jesús (2016-11-29)
    Article
    Accés obert
    In the present study, we report the discovery of a novel allosteric inhibitory site for p38a, a subclass of the mitogen-activated protein kinases (MAPK) family. The putative site was discovered after inspection of the ...
  • New insights into the stereochemical requirements of the bradykinin B1 receptor antagonist binding 

    Pérez González, Juan Jesús; Severin Lupala, Cecylia; Gomez-Gutierrez, Patricia (2016-07-21)
    Article
    Accés restringit per política de l'editorial
    Bradykinin (BK) is a nonapeptide involved in several pathophysiological conditions including among others, septic and haemorrhagic shock, anaphylaxis, arthritis, rhinitis, asthma, inflammatory bowel disease. Accordingly, ...
  • Assessment of the sampling performance of multiple-copy dynamics versus a unique trajectory 

    Pérez González, Juan Jesús; Tomás Belenguer, María Santos; Rubio Martínez, Jaime (2016-10-01)
    Article
    Accés restringit per política de l'editorial
    The goal of the present study is to ascertain the differential performance of a long molecular dynamics trajectory versus several shorter ones starting from different points in the phase space and covering the same sampling ...
  • Towards the STEM knowledge homogenization of pre-university students in 21st century MOOC: The Language for Engineering 

    Estela Carbonell, M. Rosa; Codina Mendoza, Andreu; Poblet-Puig, Jordi; Pardo Tràfach, Patricia; Puigví Burniol, Maria Àngels; Pujadas Gispert, Ester; Valls del Barrio, Susanna; Álvarez del Castillo, María Dolores; Guaus Guerrero, Ester; Hervada Sala, Carme; Macanás de Benito, Jorge; Masip Álvarez, Albert; Morillo Cazorla, Margarita; Nejjari Akhi-Elarab, Fatiha (Institute of Electrical and Electronics Engineers (IEEE), 2016)
    Comunicació de congrés
    Accés restringit per política de l'editorial
    For the past five years, Engineering students from Barcelona School of Civil Engineer in UPC BarcelonaTech have shown that educational intervention in first-year engineering programs can positively affect students’ awareness ...
  • Immobilization of antimicrobial core-shell nanospheres onto silicone for prevention of Escherichia coli biofilm formation 

    Macedo Fernandes, Margarida Maria; Ivanova, Kristina Dimitrova; Mendoza Gómez, Ernesto; Tzanov, Tzanko (2016-09-16)
    Article
    Accés restringit per política de l'editorial
    Escherichia coli (E. coli) strains are among the most frequently isolated microorganisms in urinary tract infections able to colonize the surface of urinary catheters and form biofilms. These biofilms are highly resistant ...
  • New insights into the stereochemical requirements of the bradykinin B1 receptor antagonist binding. 

    Severin Lupala, Cecylia; Gomez-Gutierrez, Patricia; Pérez González, Juan Jesús (2016-07-26)
    Article
    Accés restringit per política de l'editorial
    Bradykinin (BK) is a nonapeptide involved in several pathophysiological conditions including among others, septic and haemorrhagic shock, anaphylaxis, arthritis, rhinitis, asthma, inflammatory bowel disease. Accordingly, ...
  • Blockade of the interaction of calcineurin with foxo in astrocytes protects against Aß-induced neuronal death 

    Hervas, Rubén; Dominguez Fraile, Manuel; Garrido, Victoria; Gomez-Gutierrez, Patricia; Pérez González, Juan Jesús; Torres Aleman, Ignacio (2016-06-23)
    Article
    Accés obert
    Astrocytes actively participate in neuro-inflammatory processes associated to Alzheimer’s disease (AD), and other brain pathologies. We recently showed that an astrocyte-specific intracellular signaling pathway involving ...
  • Escherichia coli and pseudomonas aeruginosa eradication by nano-penicillin G 

    Macedo Fernandes, Margarida Maria; Ivanova, Kristina Dimitrova; Francesko, Antonio; Rivera, Diana; Torrent Burgués, Juan; Mendoza Gómez, Ernesto; Tzanov, Tzanko (2016-06-09)
    Article
    Accés restringit per política de l'editorial
    The transformation of penicillin G into nano/micro-sized spheres (nanopenicillin) using sonochemical technology was explored as a novel tool for the eradication of Gram-negative bacteria and their biofilms. Known by its ...

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