El grup està especialitzat en la síntesi i l'estudi de propietats de nous polímers. Aquests corresponen majoritàriament a materials biodegradables, per la qual cosa ens hem centrat en les tècniques que permeten el seguiment del procés de degradació (hidrolític, enzimàtic o tèrmic). També es fa l'estudi de les seves aplicacions com a sistemes dosificadors de fàrmacs (preparació de micropartícules, incorporació de l'agent actiu i seguiment del seu alliberament). Els materials es caracteritzen a través de les tècniques espectroscòpiques habituals i se?n determinen les propietats tèrmiques i mecàniques.
Les propietats dels materials polimèrics depenen de la manera com s'organitzen les macromolècules, per la qual cosa també s'estudien les fases amorfes i les diferents fases cristal·lines. La determinació de l'estructura cristal·lina es fa combinant tècniques de difracció de raigs X (pols o fibra), microscòpia electrònica i simulació molecular. També es fa la resolució, per mètodes directes i per difracció amb mon

http://futur.upc.edu/PSEP

The team specialises in the synthesis of new polymers, their physical and chemical characterisation, and the study of their properties. It is mainly involved in the development of biodegradable polymers and the study of degradation processes (hydrolytic, enzymatic and thermal). The applications of polymers as drug delivery systems are considered. The study of amorphous content and crystalline phases is also undertaken. The crystalline structures are determined by X-ray diffraction (powder or fibre), electron microscopy and molecular simulation. Direct methods are applied to monocrystals of small model compounds that are representative of polymer sequences. Research is also carried out into crystal growth (from solution or from the melt state) and the kinetics of crystallisation.

http://futur.upc.edu/PSEP

Recent Submissions

  • Dissolving hydroxyolite: a DNA molecule into its hydroxyapatite mold 

    Bertran Cànovas, Òscar; Revilla López, Guillermo; Casanovas Salas, Jordi; Valle Mendoza, Luis Javier del; Turón Dols, Pau; Puiggalí Bellalta, Jordi; Alemán Llansó, Carlos (2016-04-01)
    Article
    Restricted access - publisher's policy
    In spite of the clinical importance of hydroxyapatite (HAp), the mechanism that controls its dissolution in acidic environments remains unclear. Knowledge of such a process is highly desirable to provide better understanding ...
  • Examining the compatibility of collagen and a polythiophene derivative for the preparation of bioactive platforms 

    Soto Delgado, Jorge; Torras Costa, Juan; Valle Mendoza, Luis Javier del; Estrany Coda, Francesc; Alemán Llansó, Carlos (2015-01-09)
    Article
    Open Access
    Fundamental characteristics of bioactive platforms based on biocomposites of poly(3,4-ethylenedioxythiophene) (PEDOT) and collagen, named P(EDOT:CLG), have been examined using an experimental–computational approach. The ...
  • Study of the degradation performance (TOC, BOD and Toxicity) of Bisphenol A by the photo-Fenton process 

    Pérez Moya, Montserrat; Kaisto, Tina; Valle Mendoza, Luis Javier del (2015)
    Conference report
    Open Access
  • Polybiguanide (PHMB) loaded in PLA scaffolds displaying high hydrophobic, biocompatibility and antibacterial properties 

    Llorens Domenjó, Elena; Calderon, Silvia; Valle Mendoza, Luis Javier del; Puiggalí Bellalta, Jordi (2015-05-01)
    Article
    Restricted access - publisher's policy
    Polyhexamethylenebiguanide hydrochloride (PHMB), a low molecular weight polymer related to chlorohexidine (CHX), is a well-known antibacterial agent. In this study, polylactide (PLA) nanofibers loaded with PHMB were produced ...
  • Influence of pH on morphology and structure during hydrolytic degradation of the segmented GL-b-[GL-co-TMC-co-CL]-b-GL copolymer 

    Márquez Lobato, Yolanda; Martinez, Juan Carlos; Turón Dols, Pau; Franco García, María Lourdes; Puiggalí Bellalta, Jordi (2015-09-15)
    Article
    Open Access
    Hydrolytic degradation in media having a continuous variation of pH from 2 to 12 was studied for a copolymer having two polyglycolide hard blocks and a middle soft segment constituted by glycolide, trimethylene carbonate, ...
  • Biocompatibility and drug release behavior of scaffolds prepared by coaxial electrospinning of poly(butylene succinate) and polyethylene glycol 

    Llorens, E.; Ibañez, H; Valle Mendoza, Luis Javier del; Puiggalí Bellalta, Jordi (2015-04-01)
    Article
    Restricted access - publisher's policy
    Scaffolds constituted by electrospun microfibers of poly(ethylene glycol) (PEG) and poly(butylene succinate) (PBS) were studied. Specifically, coaxial microfibers having different core-shell distributions and compositions ...
  • Electrosprayed poly(butylene succinate) microspheres loaded with indole derivatives: A system with anticancer activity 

    Murase Fernández, Sara Keiko; Aymat, Mireia; Calvet Tarragona, Aureli; Valle Mendoza, Luis Javier del; Puiggalí Bellalta, Jordi (2015-10-01)
    Article
    Open Access
    Electrospraying of poly(butylene succinate) and its mixture with different indole derivatives was successfully performed using chloroform as solvent and relatively low flow rates and concentrations. Morphology of particles ...
  • Surviving mass extinctions through biomineralized DNA 

    Turón Dols, Pau; Puiggalí Bellalta, Jordi; Bertran Cànovas, Òscar; Alemán Llansó, Carlos (2015-12-21)
    Article
    Restricted access - publisher's policy
    Even in the worst of conditions, such as those which occurred during mass extinction events, life on Earth never totally stopped. Aggressive chemical and physical attacks able to sterilize or poison living organisms occurred ...
  • Multifunctional ternary drug-loaded electrospun scaffolds 

    Llorens Domenjó, Elena; Valle Mendoza, Luis Javier del; Puiggalí Bellalta, Jordi (2016-02-20)
    Article
    Open Access
    Multifunctional electrospun scaffolds were prepared from two polylactide (PLA) grades having slightly different d-lactide content (4.2 wt % and 2.0 wt %). Triclosan (TCS), ketoprofen (KTP), and p-coumaric acid (CUM) were ...
  • Self-assembly of tetraphenylalanine peptides 

    Mayans Tayadella, Enric; Ballano Ballano, María Gema; Casanovas Salas, Jordi; Díaz Andrade, Angélica María; Pérez Madrigal, Maria del Mar; Estrany Coda, Francesc; Puiggalí Bellalta, Jordi; Cativiela Marín, Carlos A.; Alemán Llansó, Carlos (2015-11-01)
    Article
    Restricted access - publisher's policy
    Three different tetraphenylalanine (FFFF) based peptides that differ at the N- and C-termini have been synthesized by using standard procedures to study their ability to form different nanoassemblies under a variety of ...

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