El Grup de Biomaterials, Bioemecànica i Eng. de Teixits basa la seva recerca en el desenvolupament de biomaterials per a la regeneració i/o la reparació funcional de teixits i òrgans. Es requereix el disseny de materials capaços de modular la resposta biològica del teixit receptor, donant lloc en alguns cassos a la regeneració i la neoformació dels teixits degradats, i en altres a una perfecta integració del biomaterial i la recuperació funcional perduda.

http://futur.upc.edu/BIBITE

The objectives of the group are focused on the research and development of materials for implantation into the human body, known as biomaterials. The functionality of these biomaterials is studied in the research field of biomechanics. New trends for substituting and regenerating human tissues lie within the field of tissue engineering. The BIBITE group works with all kinds of biocompatible materials for tissue substitution (hard, soft, cardiovascular, etc.). The use of some of these materials as scaffolds, which are colonised by living cells, is the basis of tissue engineering. The behaviour of implants based on these hybrids in the regeneration of the living tissues and the implantation of prostheses made from different biomaterials are evaluated by means of testing and computer modelling within the field of biomechanics.

http://futur.upc.edu/BIBITE

The objectives of the group are focused on the research and development of materials for implantation into the human body, known as biomaterials. The functionality of these biomaterials is studied in the research field of biomechanics. New trends for substituting and regenerating human tissues lie within the field of tissue engineering. The BIBITE group works with all kinds of biocompatible materials for tissue substitution (hard, soft, cardiovascular, etc.). The use of some of these materials as scaffolds, which are colonised by living cells, is the basis of tissue engineering. The behaviour of implants based on these hybrids in the regeneration of the living tissues and the implantation of prostheses made from different biomaterials are evaluated by means of testing and computer modelling within the field of biomechanics.

http://futur.upc.edu/BIBITE

Enviaments recents

  • Plasma-induced selectivity in bone cancer cells death 

    Canal Barnils, Cristina; Fontelo, Raul; Hamouda, Ines; Guillem Martí, Jordi; Cvelbar, Uros; Ginebra Molins, Maria Pau (2017-09-01)
    Article
    Accés obert
    Background Current therapies for bone cancers - either primary or metastatic – are difficult to implement and unfortunately not completely effective. An alternative therapy could be found in cold plasmas generated at ...
  • A novel hybrid nanofibrous strategy to target progenitor cells for cost-effective: In situ angiogenesis 

    Sachot, Nadege; Castaño Linares, Óscar; Oliveira, Hugo; Martí Muñoz, Joan; Roguska, Agata; Amedee, Joelle; Lewandowska, Malgorzata; Planell Estany, Josep Anton; Engel López, Elisabeth (Royal Society of Chemistry, 2016-09-22)
    Article
    Accés restringit per política de l'editorial
    Although the impact of composites based on Ti-doped calcium phosphate glasses is low compared with that of bioglass, they have been already shown to possess great potential for bone tissue engineering. Composites made of ...
  • Real-time bioluminescence imaging of cell distribution, growth, and differentiation in a three-dimensional scaffold under interstitial perfusion for tissue engineering 

    Vila, Olaia; Garrido, Cristina; Guerra Rebollo, Marta; Navarro Toro, Melba; Meca-Cortes, O; Mas, S; Engel López, Elisabeth; Rubio, Nuria; Blanco, Jeronimo (2016-09-01)
    Article
    Accés restringit per política de l'editorial
    Bioreactor systems allow safe and reproducible production of tissue constructs and functional analysis of cell behavior in biomaterials. However, current procedures for the analysis of tissue generated in biomaterials ...
  • Chitosan patterning on titanium implants 

    Gilabert Chirivella, Eduardo; Perez Feito, Ricardo; Ribeiro, Clarisse; Ribeiro, Sylvie; Correia, Daniela M.; Gonzalez Martin, Maria Luisa; Manero Planella, José María; Lanceros Méndez, Senentxu; Gallego Ferrer, Gloria; Gómez Ribelles, José Luis (2017-10-01)
    Article
    Accés obert
    Titanium and its alloys are widely used in medical implants because of their excellent properties. However, bacterial infection is a frequent cause of titanium-based implant failure and also compromises its osseointegration. ...
  • Influence of Si substitution on the reactivity of a-tricalcium phosphate 

    Motisuke, Mariana; Mestres, Gemma; Renó, Caroline O.; Carrodeguas, Raúl G.; Zavaglia, Cecilia; Ginebra Molins, Maria Pau (Elsevier, 2017-06-01)
    Article
    Accés obert
    Silicon substituted calcium phosphates have been widely studied over the last ten years due to their enhanced osteogenic properties. Notwithstanding, the role of silicon on a-TCP reactivity is not clear yet. Therefore, the ...
  • Layer-by-layer bioassembly of cellularized polylactic acid porous 3 membranes for bone tissue engineering 

    Guduric, Vera; Metz, Carole; Robin, Siadous; Bareille, Reine; Levato, Riccardo; Engel López, Elisabeth; Fricain, Jean-Christophe; Devillard, Raphaël; Luzanin, Ognjan; Catros, Sylvain (Springer, 2017-03-22)
    Article
    Accés obert
    The conventional tissue engineering is based on seeding of macroporous scaffold on its surface (“top–down” approach). The main limitation is poor cell viability in the middle of the scaffold due to poor diffusion of oxygen ...
  • Antibacterial PHAs coating for titanium implants 

    Rodriguez Contreras, Alejandra; Garcia, Yolanda; Manero Planella, José María; Rupérez de Gracia, Elisa (2017-05-01)
    Article
    Accés obert
    Biomaterial-associated infection is a serious complication of modern implantation surgery. Thus, the improvement of implant surfaces is required to avoid the first stage for biofilm formation, bacterial adhesion. The current ...
  • Osteoclast differentiation from human blood precursors on biomimetic calcium-phosphate substrates 

    Ciapetti, Gabriela; Pompo, Gemma di; Avnet, Sofia; Martini, Desirée; Díez Escudero, Anna; Montufar Jiménez, Edgar Benjamin; Ginebra Molins, Maria Pau; Baldini, Nicola (2017-03-01)
    Article
    Accés obert
    The design of synthetic bone grafts to foster bone formation is a challenge in regenerative medicine. Understanding the interaction of bone substitutes with osteoclasts is essential, since osteoclasts not only drive a ...
  • Cell adhesive peptides functionalized on CoCr alloy stimulate endothelialization and prevent thrombogenesis and restenosis 

    Castellanos, Maria Isabel; Guillem Martí, Jordi; Mas Moruno, Carlos; Díaz Ricart, Maribel; Escolar Albaladejo, Ginés; Ginebra Molins, Maria Pau; Gil Mur, Francisco Javier; Pegueroles Neyra, Marta; Manero Planella, José María (2017-04-01)
    Article
    Accés restringit per política de l'editorial
    Immobilization of bioactive peptide sequences on CoCr surfaces is an effective route to improve endothelialization, which is of great interest for cardiovascular stents. In this work, we explored the effect of physical and ...
  • Modular bioink for 3D printing of biocompatible hydrogels: sol-gel polymerization of hybrid peptides and polymers 

    Echalier, Cecile; Levato, Riccardo; Mateos Timoneda, Miguel Ángel; Castaño Linares, Óscar; Dejean, S; Garric, X; Pinese, C; Noël, D; Engel López, Elisabeth; Martinez, J; Mehdi, A; Subra, Gilles (Royal Society of Chemistry, 2017-02-21)
    Article
    Accés restringit per política de l'editorial
    An unprecedented generic system allowing the 3D printing of peptide-functionalized hydrogels by soft sol–gel inorganic polymerization is presented. Hybrid silylated inorganic/bioorganic blocks are mixed in biological buffer ...

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