El Grup de Biomaterials, Bioemecànica i Eng. de Teixits basa la seva recerca en el desenvolupament de biomaterials per a la regeneració i/o la reparació funcional de teixits i òrgans. Es requereix el disseny de materials capaços de modular la resposta biològica del teixit receptor, donant lloc en alguns cassos a la regeneració i la neoformació dels teixits degradats, i en altres a una perfecta integració del biomaterial i la recuperació funcional perduda.

http://futur.upc.edu/BIBITE

The objectives of the group are focused on the research and development of materials for implantation into the human body, known as biomaterials. The functionality of these biomaterials is studied in the research field of biomechanics. New trends for substituting and regenerating human tissues lie within the field of tissue engineering. The BIBITE group works with all kinds of biocompatible materials for tissue substitution (hard, soft, cardiovascular, etc.). The use of some of these materials as scaffolds, which are colonised by living cells, is the basis of tissue engineering. The behaviour of implants based on these hybrids in the regeneration of the living tissues and the implantation of prostheses made from different biomaterials are evaluated by means of testing and computer modelling within the field of biomechanics.

http://futur.upc.edu/BIBITE

The objectives of the group are focused on the research and development of materials for implantation into the human body, known as biomaterials. The functionality of these biomaterials is studied in the research field of biomechanics. New trends for substituting and regenerating human tissues lie within the field of tissue engineering. The BIBITE group works with all kinds of biocompatible materials for tissue substitution (hard, soft, cardiovascular, etc.). The use of some of these materials as scaffolds, which are colonised by living cells, is the basis of tissue engineering. The behaviour of implants based on these hybrids in the regeneration of the living tissues and the implantation of prostheses made from different biomaterials are evaluated by means of testing and computer modelling within the field of biomechanics.

http://futur.upc.edu/BIBITE

Enviaments recents

  • Extent and mechanism of phase separation during the extrusion of calcium phosphate pastes 

    O'Neill, Rory; McCarthy, Hellen O.; Cunningham, Eoin; Montufar Jimenez, Edgar Benjamin; Ginebra Molins, Maria Pau; Wilson, Ian; Lennon, Alex; Dunne, Nicholas (Springer, 2016-02)
    Article
    Accés obert
    The aim of this study was to increase understanding of the mechanism and dominant drivers influencing phase separation during ram extrusion of calcium phosphate (CaP) paste for orthopaedic applications. The liquid content ...
  • avß3- or a5ß1-Integrin-Selective Peptidomimetics for Surface Coating 

    Mas Moruno, Carlos; Fraioli, Roberta; Rechenmacher, Florian; Neubauer, Stefanie; Kapp, Tobias G.; Kessler, Horst (2016-06-13)
    Article
    Accés restringit per política de l'editorial
    Engineering biomaterials with integrin-binding activity is a very powerful approach to promote cell adhesion, modulate cell behavior, and induce specific biological responses at the surface level. The aim of this Review ...
  • Biofunctional polyethylene glycol coatings on titanium: an in vitro-based comparison of functionalization methods 

    Buxadera Palomero, Judit; Calvo muñoz, Cristina; Torrent Camarero, Sergi; Gil Mur, Francisco Javier; Mas Moruno, Carlos; Canal Barnils, Cristina; Rodríguez Rius, Daniel (Elsevier, 2017-04-01)
    Article
    Accés restringit per política de l'editorial
    Three methods for the production of Polyethylene glycol (PEG) coatings on titanium are compared, i.e. plasma polymerization, electrodeposition and silanization. The compared deposition methods presented similar wettability ...
  • A comprehensive evaluation of the activity and selectivity profile of ligands for RGD-binding integrins 

    Kapp, Tobias G.; Rechenmacher, Florian; Neubauer, Stefanie; Maltsev, Oleg V.; Cavalcanti-Adam, Elisabetta Ada; Zarka, Revital; Reuning, Ute; Notni, Johannes; Wester, Hans-Jürgen; Mas Moruno, Carlos; Spatz, Joachim; Geiger, Benjamin; Kessler, Horst (Macmillan Publishers, 2017-01-11)
    Article
    Accés obert
    Integrins, a diverse class of heterodimeric cell surface receptors, are key regulators of cell structure and behaviour, affecting cell morphology, proliferation, survival and differentiation. Consequently, mutations in ...
  • Polylactic acid organogel as versatile scaffolding technique 

    Punet, Xavier; Levato, Riccardo; Bataille, Isabelle; Letourneur, Didier; Engel López, Elisabeth; Mateos Timoneda, Miguel Ángel (Elsevier, 2017-03-24)
    Article
    Accés restringit per política de l'editorial
    Tissue engineering requires scaffolding techniques based on non-toxic processes that permits the fabrication of constructs with tailored properties. Here, a two-step methodology based on the gelation and precipitation of ...
  • Plasma-inspired biomaterials 

    Cvelbar, Uros; Canal Barnils, Cristina; Hori, Masaru (2017-02-02)
    Article
    Accés restringit per política de l'editorial
    The first questions which arise when one looks at the title of this special issue are what are plasma-inspired biomaterials, and what is this Special Issue of Journal of Physics D: Applied Physics (JPhysD) all about? ...
  • Functionalization of CoCr surfaces with cell adhesive peptides to promote HUVECs adhesion and proliferation 

    Castellanos, Maria Isabel; Mas Moruno, Carlos; Grau, Anna; Serra-Picamal, Xavier; Trepat, Xavier; Albericio Palomera, Fernando; Joner, Michael; Gil Mur, Francisco Javier; Ginebra Molins, Maria Pau; Manero Planella, José María; Pegueroles Neyra, Marta (2017-01-30)
    Article
    Accés restringit per política de l'editorial
    Biomimetic surface modification with peptides that have specific cell-binding moieties is a promising approach to improve endothelialization of metal-based stents. In this study, we functionalized CoCr surfaces with RGDS, ...
  • Self-hardening and thermoresponsive alpha tricalcium phosphate/pluronic pastes 

    Maazouz, Yassine; Montufar Jimenez, Edgar Benjamin; Malbert, Julien; Español Pons, Montserrat; Ginebra Molins, Maria Pau (2017-02)
    Article
    Accés restringit per política de l'editorial
    Although calcium phosphate cements (CPCs) are used for bone regeneration in a wide range of clinical applications, various physicochemical phenomena are known to hinder their potential use in minimally invasive surgery or ...
  • Critical review: injectability of calcium phosphate pastes and cements 

    Ginebra Molins, Maria Pau; O'Neill, Rory; Montufar Jimenez, Edgar Benjamin; Wilson, D.I.; Lennon, A.; Dunne, Nicholas (2016-11-09)
    Article
    Accés restringit per política de l'editorial
    Calcium phosphate cements (CPC) have seen clinical success in many dental and orthopaedic applications in recent years. The properties of CPC essential for clinical success are reviewed in this article, which includes ...
  • Biofunctionalization of patterned PLLA surfaces with RGD, REDV and YIGSR peptides to promote endothelial cells adhesion and migration 

    Schieber, Tiabo A.; Mas Moruno, Carlos; Gil Mur, Francisco Javier; Mücklich, F.; Pegueroles Neyra, Marta (2016)
    Comunicació de congrés
    Accés obert
    Angioplasty and stent implantation open the blocked artery and restore proper blood flow after atherosclerosis disease. Despite their utility, intracoronary stents induce two types of complications: in-stent restenosis and ...

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