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Electrospinning of gelatin fibers using solutions with low acetic acid concentration: effect of solvent composition on both diameter of electrospun fibers and cytotoxicity
dc.contributor.author | Erencia Millan, Maria Salud |
dc.contributor.author | Cano Casas, Francesc |
dc.contributor.author | Tornero García, José Antonio |
dc.contributor.author | Macedo Fernandes, Margarida Maria |
dc.contributor.author | Tzanov, Tzanko |
dc.contributor.author | Macanás de Benito, Jorge |
dc.contributor.author | Carrillo Navarrete, Fernando |
dc.contributor.other | Universitat Politècnica de Catalunya. Institut d'Investigació Tèxtil i Cooperació Industrial de Terrassa |
dc.contributor.other | Universitat Politècnica de Catalunya. Departament d'Enginyeria Química |
dc.date.accessioned | 2015-04-20T12:35:07Z |
dc.date.available | 2016-02-15T01:30:34Z |
dc.date.created | 2015-03-13 |
dc.date.issued | 2015-03-13 |
dc.identifier.citation | Erencia, M. [et al.]. Electrospinning of gelatin fibers using solutions with low acetic acid concentration: effect of solvent composition on both diameter of electrospun fibers and cytotoxicity. "Journal of Applied Polymer Science (online)", 13 Març 2015, vol. 132, núm. 25, p. 42115 (1/11)-42115 (11(11). |
dc.identifier.issn | 1097-4628 |
dc.identifier.uri | http://hdl.handle.net/2117/27456 |
dc.description.abstract | Gelatin fibers were prepared by electrospinning of gelatin/acetic acid/water ternary mixtures with the aim of studying the feasibility of fabricating gelatin nanofiber mats at room temperature using an alternative benign solvent by significantly reducing the acetic acid concentration. The results showed that gelatin nanofibers can be optimally electrospun with low acetic acid concentration (25% v/v) combined with gelatin concentrations higher than 300 mg/ml. Both gelatin solutions and electrospun gelatin mats (prepared with different acetic acid aqueous solutions) were analyzed by FTIR and DSC techniques in order to determine the chemical and structure changes of the polymer. The electrospun gelatin mats fabricated from solutions with low acetic acid content showed some advantages as the maintenance of the decomposition temperature of the pure gelatin (~230ºC) and the reduction of the acid content on electrospun mats, which allowed to reach a cell viability upper than 90% (analyzed by cell viability test using human dermal fibroblast and embryonic kidney cells). This study has also analyzed the influence of gelatin and acetic acid concentration both on the solution viscosity and the electrospun fiber diameter, obtaining a clear relationship between these parameters |
dc.language.iso | eng |
dc.publisher | Wiley |
dc.rights | Attribution 3.0 Spain |
dc.rights.uri | http://creativecommons.org/licenses/by/3.0/es/ |
dc.subject | Àrees temàtiques de la UPC::Enginyeria química::Indústries químiques::Química tèxtil |
dc.subject | Àrees temàtiques de la UPC::Enginyeria tèxtil ::Fibres tèxtils |
dc.subject.lcsh | Electrospinning |
dc.subject.lcsh | Textile fibers |
dc.subject.lcsh | Nanofibers |
dc.subject.other | electrospinning |
dc.subject.other | nanofibers |
dc.subject.other | mat |
dc.subject.other | cell viability |
dc.subject.other | gelatin |
dc.subject.other | acetic acid |
dc.subject.other | biomaterials |
dc.subject.other | electrospinning |
dc.subject.other | fibers |
dc.title | Electrospinning of gelatin fibers using solutions with low acetic acid concentration: effect of solvent composition on both diameter of electrospun fibers and cytotoxicity |
dc.type | Article |
dc.subject.lemac | Filatura -- Innovacions tecnològiques |
dc.subject.lemac | Materials -- Biotecnologia |
dc.subject.lemac | Fibres |
dc.contributor.group | Universitat Politècnica de Catalunya. TECTEX - Grup de Recerca en Tecnologia Tèxtil |
dc.contributor.group | Universitat Politècnica de Catalunya. GBMI - Grup de Biotecnologia Molecular i Industrial |
dc.contributor.group | Universitat Politècnica de Catalunya. POLQUITEX - Materials Polimérics i Química Téxtil |
dc.identifier.doi | 10.1002/app.42115 |
dc.relation.publisherversion | http://onlinelibrary.wiley.com/doi/10.1002/app.42115/abstract |
dc.rights.access | Open Access |
local.identifier.drac | 15579055 |
dc.description.version | Postprint (author’s final draft) |
local.citation.author | Erencia, M.; Cano, F.; Tornero, J.; Macedo, M.M.; Tzanov, T.; Macanas, J.; Carrillo, F. |
local.citation.publicationName | Journal of Applied Polymer Science (online) |
local.citation.volume | 132 |
local.citation.number | 25 |
local.citation.startingPage | 42115 (1/11) |
local.citation.endingPage | 42115 (11(11) |
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