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dc.contributor.authorMassanet Vila, Raimon
dc.contributor.authorPadró Capmany, Teresa
dc.contributor.authorCardús, Anna
dc.contributor.authorBadimón, Lina
dc.contributor.authorCaminal Magrans, Pere
dc.contributor.authorPerera Lluna, Alexandre
dc.contributor.otherUniversitat Politècnica de Catalunya. Departament d'Enginyeria de Sistemes, Automàtica i Informàtica Industrial
dc.date.accessioned2012-01-11T10:56:18Z
dc.date.available2012-01-11T10:56:18Z
dc.date.created2011
dc.date.issued2011
dc.identifier.citationMassanet-Vila, R. [et al.]. Analysis of incomplete gene expression dataset through protein-protein interaction information. A: IEEE Engineering in Medicine and Biology Society. "Proceedings of the 33rd Annual International Conference of the IEEE EMBS". Boston: 2011, p. 6845-6848.
dc.identifier.isbn978-1-4244-4122-8
dc.identifier.urihttp://hdl.handle.net/2117/14465
dc.description.abstractThis paper shows a graph based method to analyze proteomic expression data. The method allows the prediction of the expression of genes not measured by the gene expression technology based on the local connectivity properties of the measured differentially expressed gene set. The prediction of the expression jointly with the stability of this prediction as a function of the variation of the initial expressed set is computed. The method is able to correctly predict one third of the proteins with independence of variations on the selection of the initial set. The algorithm is validated through a Matrix-Assisted Laser Desorption/Ionization Time of Flight Mass Spectrometer (MALDI-TOF) protein expression experiment aiming the study of the protein expression patterns and post-translational modifications in human endothelial vascular cells exposed to atherosclerotic levels of Low Density Lipoproteins (LDL).
dc.format.extent4 p.
dc.language.isoeng
dc.subjectÀrees temàtiques de la UPC::Enginyeria biomèdica::Electrònica biomèdica
dc.subject.lcshBioinformatics
dc.subject.lcshGenomics -- Data processing
dc.subject.lcshProteomics
dc.titleAnalysis of incomplete gene expression dataset through protein-protein interaction information
dc.typeConference report
dc.subject.lemacProteòmica
dc.subject.lemacGenòmica -- Processament de dades
dc.contributor.groupUniversitat Politècnica de Catalunya. SISBIO - Senyals i Sistemes Biomèdics
dc.identifier.doi10.1109/IEMBS.2011.6091688
dc.description.peerreviewedPeer Reviewed
dc.rights.accessRestricted access - publisher's policy
local.identifier.drac8953668
dc.description.versionPostprint (published version)
local.citation.authorMassanet-Vila, R.; Padró, T.; Cardús, A.; Badimón, L.; Caminal, P.; Perera, A.
local.citation.contributorIEEE Engineering in Medicine and Biology Society
local.citation.pubplaceBoston
local.citation.publicationNameProceedings of the 33rd Annual International Conference of the IEEE EMBS
local.citation.startingPage6845
local.citation.endingPage6848


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