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Analysis of incomplete gene expression dataset through protein-protein interaction information
dc.contributor.author | Massanet Vila, Raimon |
dc.contributor.author | Padró Capmany, Teresa |
dc.contributor.author | Cardús, Anna |
dc.contributor.author | Badimón, Lina |
dc.contributor.author | Caminal Magrans, Pere |
dc.contributor.author | Perera Lluna, Alexandre |
dc.contributor.other | Universitat Politècnica de Catalunya. Departament d'Enginyeria de Sistemes, Automàtica i Informàtica Industrial |
dc.date.accessioned | 2012-01-11T10:56:18Z |
dc.date.available | 2012-01-11T10:56:18Z |
dc.date.created | 2011 |
dc.date.issued | 2011 |
dc.identifier.citation | Massanet-Vila, R. [et al.]. Analysis of incomplete gene expression dataset through protein-protein interaction information. A: IEEE Engineering in Medicine and Biology Society. "Proceedings of the 33rd Annual International Conference of the IEEE EMBS". Boston: 2011, p. 6845-6848. |
dc.identifier.isbn | 978-1-4244-4122-8 |
dc.identifier.uri | http://hdl.handle.net/2117/14465 |
dc.description.abstract | This paper shows a graph based method to analyze proteomic expression data. The method allows the prediction of the expression of genes not measured by the gene expression technology based on the local connectivity properties of the measured differentially expressed gene set. The prediction of the expression jointly with the stability of this prediction as a function of the variation of the initial expressed set is computed. The method is able to correctly predict one third of the proteins with independence of variations on the selection of the initial set. The algorithm is validated through a Matrix-Assisted Laser Desorption/Ionization Time of Flight Mass Spectrometer (MALDI-TOF) protein expression experiment aiming the study of the protein expression patterns and post-translational modifications in human endothelial vascular cells exposed to atherosclerotic levels of Low Density Lipoproteins (LDL). |
dc.format.extent | 4 p. |
dc.language.iso | eng |
dc.subject | Àrees temàtiques de la UPC::Enginyeria biomèdica::Electrònica biomèdica |
dc.subject.lcsh | Bioinformatics |
dc.subject.lcsh | Genomics -- Data processing |
dc.subject.lcsh | Proteomics |
dc.title | Analysis of incomplete gene expression dataset through protein-protein interaction information |
dc.type | Conference report |
dc.subject.lemac | Proteòmica |
dc.subject.lemac | Genòmica -- Processament de dades |
dc.contributor.group | Universitat Politècnica de Catalunya. SISBIO - Senyals i Sistemes Biomèdics |
dc.identifier.doi | 10.1109/IEMBS.2011.6091688 |
dc.description.peerreviewed | Peer Reviewed |
dc.rights.access | Restricted access - publisher's policy |
local.identifier.drac | 8953668 |
dc.description.version | Postprint (published version) |
local.citation.author | Massanet-Vila, R.; Padró, T.; Cardús, A.; Badimón, L.; Caminal, P.; Perera, A. |
local.citation.contributor | IEEE Engineering in Medicine and Biology Society |
local.citation.pubplace | Boston |
local.citation.publicationName | Proceedings of the 33rd Annual International Conference of the IEEE EMBS |
local.citation.startingPage | 6845 |
local.citation.endingPage | 6848 |