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Supernormal conduction in cardiac tissue promotes concordant alternans and action potential bunching
dc.contributor.author | Echebarría Domínguez, Blas |
dc.contributor.author | Roeder, Georg |
dc.contributor.author | Engel, Harald |
dc.contributor.author | Davidsen, Joern |
dc.contributor.author | Baer, Markus |
dc.contributor.other | Universitat Politècnica de Catalunya. Departament de Física Aplicada |
dc.date.accessioned | 2011-05-20T09:28:50Z |
dc.date.available | 2011-05-20T09:28:50Z |
dc.date.created | 2011-04-04 |
dc.date.issued | 2011-04-04 |
dc.identifier.citation | Echebarria, B. [et al.]. Supernormal conduction in cardiac tissue promotes concordant alternans and action potential bunching. "Physical review E: statistical, nonlinear, and soft matter physics", 04 Abril 2011, vol. 83, núm. 4, p. 1-4. |
dc.identifier.issn | 1539-3755 |
dc.identifier.uri | http://hdl.handle.net/2117/12622 |
dc.description.abstract | Supernormal conduction (SNC) in excitable cardiac tissue refers to an increase of pulse (or action potential) velocity with decreasing distance to the preceding pulse. Here we employ a simple ionic model to study the effect of SNC on the propagation of action potentials (APs) and the phenomenology of alternans in excitable cardiac tissue. We use bifurcation analysis and simulations to study attraction between propagating APs caused by SNC that leads to AP pairs and bunching. It is shown that SNC stabilizes concordant alternans in arbitrarily long paced one-dimensional cables. As a consequence, spiral waves in two-dimensional tissue simulations exhibit straight nodal lines for SNC in contrast to spiraling ones in the case of normal conduction |
dc.format.extent | 4 p. |
dc.language.iso | eng |
dc.rights | Attribution-NonCommercial-NoDerivs 3.0 Spain |
dc.rights.uri | http://creativecommons.org/licenses/by-nc-nd/3.0/es/ |
dc.subject | Àrees temàtiques de la UPC::Física |
dc.subject | Àrees temàtiques de la UPC::Edificació::Elements constructius d'edificis |
dc.subject.lcsh | Cardiac dynamics |
dc.subject.lcsh | Nonlinear dynamics and chaos |
dc.title | Supernormal conduction in cardiac tissue promotes concordant alternans and action potential bunching |
dc.type | Article |
dc.subject.lemac | Sistemes dinàmics |
dc.contributor.group | Universitat Politècnica de Catalunya. NOLIN - Física No-Lineal i Sistemes Fora de l'Equilibri |
dc.identifier.doi | 10.1103/PhysRevE.83.040902 |
dc.relation.publisherversion | http://link.aps.org/doi/10.1103/PhysRevE.83.040902 |
dc.rights.access | Open Access |
local.identifier.drac | 5737449 |
dc.description.version | Postprint (published version) |
local.citation.author | Echebarria, B.; Roeder, G.; Engel, H.; Davidsen, J.; Baer, M. |
local.citation.publicationName | Physical review E: statistical, nonlinear, and soft matter physics |
local.citation.volume | 83 |
local.citation.number | 4 |
local.citation.startingPage | 1 |
local.citation.endingPage | 4 |
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