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Títol: Degradable Poly(ester amide)s for biomedical aplications
Autor: Rodríguez Galán, Rafael Alfonso
Franco García, María Lourdes
Puiggalí Bellalta, Jordi
Altres autors/autores: Universitat Politècnica de Catalunya. Departament d'Enginyeria Química
Matèries: Àrees temàtiques de la UPC::Enginyeria química
Polymers
Biodegradation
Polyesters.
Poliester
Biodegradació
Tipus de document: Article
Descripció: Poly(ester amide)s are an emerging group of biodegradable polymers that may cover both commodity and speciality applications. These polymers have ester and amide groups on their chemical structure which are of a degradable character and provide good thermal and mechanical properties. In this sense, the strong hydrogen‑bonding interactions between amide groups may counter some typical weaknesses of aliphatic polyesters like for example poly(e-caprolactone). Poly(ester amide)s can be prepared from different monomers and following different synthetic methodologies which lead to polymers with random, blocky and ordered microstructures. Properties like hydrophilic/hydrophobic ratio and biodegradability can easily be tuned. During the last decade a great effort has been made to get functionalized poly(ester amide)s by incorporation of a-amino acids with hydroxyl, carboxyl and amine pendant groups and also by incorporation of carbon-carbon double bonds in both the polymer main chain and the side groups. Specific applications of these materials in the biomedical field are just being developed and are reviewed in this work (e.g., controlled drug delivery systems, hydrogels, tissue engineering and other uses like adhesives and smart materials) together with the main families of functionalized poly(ester amide)s that have been developed to date.
Altres identificadors i accés: Rodriguez, R.; Franco, M.; Puiggali, J. Degradable Poly(ester amide)s for biomedical aplications. "Polymers", 27 Desembre 2010, vol. 3, núm. 1, p. 65-99.
2073-4360
http://hdl.handle.net/2117/11653
10.3390/polym3010065
Disponible al dipòsit:E-prints UPC
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