The goal of this study is to analyze how a wing constructed in such a way that has different in-built angles of attack behaves in front of a conventional built wing. The flow around the wing profile of the Airbus A380 was simulated by CFD and the normalized aerodynamical data (lift, drag, aerodynamic center etc. ) was be obtained. Next, the wing profile was modified by changing the in-built angle of attack progressively from root to tip. The aerodynamic behaviouf of the resulting twisted wing profile was simulated by CFD and the aerodynamic data was compared with that of the standard wing. The potential benefits and difficulties of the mixed profiles wing was analysed both from the aerodynamic (flight stability, fuel consumption, etc.) and the structural (induced stress, construction methods, and available materials) points of view.